Prevalence of diabetic retinopathy in relation to age at onset of the diabetes, treatment, duration and glycemic control
(1996) In Acta Ophthalmologica Scandinavica 74(6). p.523-527- Abstract
To study the frequency of diabetic retinopathy in relation to age at diagnosis, treatment, duration of diabetes and glycemic control as measured by means of HbA(1c) levels, we performed a cross-sectional, register-based study in the Helsingborg area of southern Sweden, comprising 2232 diabetic patients. Of the known diabetic population < 75 years old, approximately 70% were estimated to be included. We graded retinopathy according to the alternative classification of the Wisconsin study. With an age at diagnosis < 30 years (19% of patients) the prevalence of retinopathy was 64%, whereas with an age at diagnosis ≤ 30 years the prevalence of retinopathy was 57% in insulin-treated, and 26% in non-insulin treated patients. Levels of... (More)
To study the frequency of diabetic retinopathy in relation to age at diagnosis, treatment, duration of diabetes and glycemic control as measured by means of HbA(1c) levels, we performed a cross-sectional, register-based study in the Helsingborg area of southern Sweden, comprising 2232 diabetic patients. Of the known diabetic population < 75 years old, approximately 70% were estimated to be included. We graded retinopathy according to the alternative classification of the Wisconsin study. With an age at diagnosis < 30 years (19% of patients) the prevalence of retinopathy was 64%, whereas with an age at diagnosis ≤ 30 years the prevalence of retinopathy was 57% in insulin-treated, and 26% in non-insulin treated patients. Levels of glycated hemoglobin and duration of diabetes were associated with retinopathy in the group with younger onset. In the older-onset group, there was a relationship between retinopathy and duration of diabetes and insulin treatment; glycated hemoglobin had a relationship which was of borderline significance with any retinopathy, but clearly significant with the pooled group: severe non-proliferative, proliferative retinopathy and/or macular edema. Hyperglycemia and duration of diabetes were thus associated with retinopathy in both younger- and older-onset diabetes, but hyperglycemia less so in the older-onset group.
(Less)
- author
- Henricsson, Marianne LU ; Nilsson, Anders ; Groop, Leif LU ; Heijl, Anders LU and Janzon, Lars LU
- organization
- publishing date
- 1996-12
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Diabetes mellitus, Diabetic retinopathy, Glycemic control, Insulin treatment
- in
- Acta Ophthalmologica Scandinavica
- volume
- 74
- issue
- 6
- pages
- 523 - 527
- publisher
- Wiley
- external identifiers
-
- pmid:9017034
- scopus:0030482581
- ISSN
- 1395-3907
- DOI
- 10.1111/j.1600-0420.1996.tb00727.x
- language
- English
- LU publication?
- yes
- id
- 1a280d3c-a763-4b35-ab9a-03e5ee280ae6
- date added to LUP
- 2019-06-27 20:47:06
- date last changed
- 2024-03-03 17:59:16
@article{1a280d3c-a763-4b35-ab9a-03e5ee280ae6,
abstract = {{<p>To study the frequency of diabetic retinopathy in relation to age at diagnosis, treatment, duration of diabetes and glycemic control as measured by means of HbA(1c) levels, we performed a cross-sectional, register-based study in the Helsingborg area of southern Sweden, comprising 2232 diabetic patients. Of the known diabetic population < 75 years old, approximately 70% were estimated to be included. We graded retinopathy according to the alternative classification of the Wisconsin study. With an age at diagnosis < 30 years (19% of patients) the prevalence of retinopathy was 64%, whereas with an age at diagnosis ≤ 30 years the prevalence of retinopathy was 57% in insulin-treated, and 26% in non-insulin treated patients. Levels of glycated hemoglobin and duration of diabetes were associated with retinopathy in the group with younger onset. In the older-onset group, there was a relationship between retinopathy and duration of diabetes and insulin treatment; glycated hemoglobin had a relationship which was of borderline significance with any retinopathy, but clearly significant with the pooled group: severe non-proliferative, proliferative retinopathy and/or macular edema. Hyperglycemia and duration of diabetes were thus associated with retinopathy in both younger- and older-onset diabetes, but hyperglycemia less so in the older-onset group.</p>}},
author = {{Henricsson, Marianne and Nilsson, Anders and Groop, Leif and Heijl, Anders and Janzon, Lars}},
issn = {{1395-3907}},
keywords = {{Diabetes mellitus; Diabetic retinopathy; Glycemic control; Insulin treatment}},
language = {{eng}},
number = {{6}},
pages = {{523--527}},
publisher = {{Wiley}},
series = {{Acta Ophthalmologica Scandinavica}},
title = {{Prevalence of diabetic retinopathy in relation to age at onset of the diabetes, treatment, duration and glycemic control}},
url = {{http://dx.doi.org/10.1111/j.1600-0420.1996.tb00727.x}},
doi = {{10.1111/j.1600-0420.1996.tb00727.x}},
volume = {{74}},
year = {{1996}},
}