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Molecular imprinting on the nanoscale rapid detection of cells

Idil, Neslihan ; Aslıyüce, Sevgi ; Perçin, Işık and Mattiasson, Bo LU (2023) p.107-130
Abstract

In the last 30 years, molecular imprinting has been evidenced as a desirable approach to design artificial, specific, and selective recognition sites for the target molecules/cells. Molecularly imprinted polymers (MIPs) are the most encouraging reflection of the advanced area of biomimetics and have attracted important popularity for the detection of many types of molecules including peptides, proteins, and even cells. In this context, imprinting of relatively small molecules is well identified; however, imprinting of cells still remains a big challenge from past to present. In this chapter, the importance of molecular recognition mechanisms in the renovation of artificial regions was stated, and molecular imprinting strategies used for... (More)

In the last 30 years, molecular imprinting has been evidenced as a desirable approach to design artificial, specific, and selective recognition sites for the target molecules/cells. Molecularly imprinted polymers (MIPs) are the most encouraging reflection of the advanced area of biomimetics and have attracted important popularity for the detection of many types of molecules including peptides, proteins, and even cells. In this context, imprinting of relatively small molecules is well identified; however, imprinting of cells still remains a big challenge from past to present. In this chapter, the importance of molecular recognition mechanisms in the renovation of artificial regions was stated, and molecular imprinting strategies used for cell detection were presented. In this respect, cell lithography, epitope imprinting, whole-cell imprinting technology involving cell-mediated lithography, and microcontact imprinting approaches were explained. The applications of nanoparticles, quantum dots, sensing platforms, and imaging approaches within the extensive group of nano-MIPs were discussed in terms of microbial, viral, and mammalian cell detection. In conclusion, the challenges and future perspectives on the construction of nano-MIPs aiming for cell detection were outlined.

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Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
cell detection, Molecular imprinting, nanosized materials, sensing
host publication
Biophysics at the Nanoscale : Applications of Functional Materials - Applications of Functional Materials
pages
24 pages
publisher
ScienceDirect, Elsevier
external identifiers
  • scopus:85179244697
ISBN
9780443153600
9780443153594
DOI
10.1016/B978-0-443-15359-4.00012-7
language
English
LU publication?
yes
id
1b114b6e-2f24-4ef4-89f4-db6f7a8d9519
date added to LUP
2024-01-11 10:43:20
date last changed
2024-04-12 03:36:46
@inbook{1b114b6e-2f24-4ef4-89f4-db6f7a8d9519,
  abstract     = {{<p>In the last 30 years, molecular imprinting has been evidenced as a desirable approach to design artificial, specific, and selective recognition sites for the target molecules/cells. Molecularly imprinted polymers (MIPs) are the most encouraging reflection of the advanced area of biomimetics and have attracted important popularity for the detection of many types of molecules including peptides, proteins, and even cells. In this context, imprinting of relatively small molecules is well identified; however, imprinting of cells still remains a big challenge from past to present. In this chapter, the importance of molecular recognition mechanisms in the renovation of artificial regions was stated, and molecular imprinting strategies used for cell detection were presented. In this respect, cell lithography, epitope imprinting, whole-cell imprinting technology involving cell-mediated lithography, and microcontact imprinting approaches were explained. The applications of nanoparticles, quantum dots, sensing platforms, and imaging approaches within the extensive group of nano-MIPs were discussed in terms of microbial, viral, and mammalian cell detection. In conclusion, the challenges and future perspectives on the construction of nano-MIPs aiming for cell detection were outlined.</p>}},
  author       = {{Idil, Neslihan and Aslıyüce, Sevgi and Perçin, Işık and Mattiasson, Bo}},
  booktitle    = {{Biophysics at the Nanoscale : Applications of Functional Materials}},
  isbn         = {{9780443153600}},
  keywords     = {{cell detection; Molecular imprinting; nanosized materials; sensing}},
  language     = {{eng}},
  pages        = {{107--130}},
  publisher    = {{ScienceDirect, Elsevier}},
  title        = {{Molecular imprinting on the nanoscale rapid detection of cells}},
  url          = {{http://dx.doi.org/10.1016/B978-0-443-15359-4.00012-7}},
  doi          = {{10.1016/B978-0-443-15359-4.00012-7}},
  year         = {{2023}},
}