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Neural activity, alertness and visual orientation in intact and unilaterally labyrinthectomized rabbits

Pyykkö, I. and Magnusson, M LU (1987) In ORL; journal for oto-rhino-laryngology and its related specialties 49(1). p.26-34
Abstract

Electrical brain activity and eye movements were recorded in 10 intact and 6 unilaterally labyrinthectomized rabbits, each with implanted electrodes. The frequency of optokinetic nystagmus (OKN) and a 10-second aggregate of theta waves in the dorsal hippocampus were determined after exposure of the animals to sound, vibration and optokinetic stimulation. Each stimulus used caused significant increases in OKN and theta activity. Vibratory stimuli caused stronger increases in OKN and theta activity than did sound stimuli. Not only was OKN significantly reduced after unilateral labyrinthectomy (UL), but alerting the rabbit with sound or vibration failed to restore the responses to normal, and hippocampal EEG responses to sound, vibration... (More)

Electrical brain activity and eye movements were recorded in 10 intact and 6 unilaterally labyrinthectomized rabbits, each with implanted electrodes. The frequency of optokinetic nystagmus (OKN) and a 10-second aggregate of theta waves in the dorsal hippocampus were determined after exposure of the animals to sound, vibration and optokinetic stimulation. Each stimulus used caused significant increases in OKN and theta activity. Vibratory stimuli caused stronger increases in OKN and theta activity than did sound stimuli. Not only was OKN significantly reduced after unilateral labyrinthectomy (UL), but alerting the rabbit with sound or vibration failed to restore the responses to normal, and hippocampal EEG responses to sound, vibration or optokinetic stimulus were significantly reduced. The findings indicate that a visual orientation reflex is normally improved by simultaneous sensory stimulation. Reduced response to stimuli after UL affects not only orientational reflexes but other sensory responses as well, and is accompanied by a reduced state of alertness.

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organization
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type
Contribution to journal
publication status
published
subject
keywords
Acoustic Stimulation, Animals, Ear, Inner, Electroencephalography, Hippocampus, Nystagmus, Physiologic, Orientation, Rabbits, Vibration, Journal Article, Research Support, Non-U.S. Gov't
in
ORL; journal for oto-rhino-laryngology and its related specialties
volume
49
issue
1
pages
9 pages
publisher
Karger
external identifiers
  • scopus:0023122821
ISSN
0301-1569
language
English
LU publication?
yes
id
1ba97943-67e8-47de-a2e6-90d1777f382c
date added to LUP
2017-05-03 13:04:53
date last changed
2017-06-07 14:14:15
@article{1ba97943-67e8-47de-a2e6-90d1777f382c,
  abstract     = {<p>Electrical brain activity and eye movements were recorded in 10 intact and 6 unilaterally labyrinthectomized rabbits, each with implanted electrodes. The frequency of optokinetic nystagmus (OKN) and a 10-second aggregate of theta waves in the dorsal hippocampus were determined after exposure of the animals to sound, vibration and optokinetic stimulation. Each stimulus used caused significant increases in OKN and theta activity. Vibratory stimuli caused stronger increases in OKN and theta activity than did sound stimuli. Not only was OKN significantly reduced after unilateral labyrinthectomy (UL), but alerting the rabbit with sound or vibration failed to restore the responses to normal, and hippocampal EEG responses to sound, vibration or optokinetic stimulus were significantly reduced. The findings indicate that a visual orientation reflex is normally improved by simultaneous sensory stimulation. Reduced response to stimuli after UL affects not only orientational reflexes but other sensory responses as well, and is accompanied by a reduced state of alertness.</p>},
  author       = {Pyykkö, I. and Magnusson, M},
  issn         = {0301-1569},
  keyword      = {Acoustic Stimulation,Animals,Ear, Inner,Electroencephalography,Hippocampus,Nystagmus, Physiologic,Orientation,Rabbits,Vibration,Journal Article,Research Support, Non-U.S. Gov't},
  language     = {eng},
  number       = {1},
  pages        = {26--34},
  publisher    = {Karger},
  series       = {ORL; journal for oto-rhino-laryngology and its related specialties},
  title        = {Neural activity, alertness and visual orientation in intact and unilaterally labyrinthectomized rabbits},
  volume       = {49},
  year         = {1987},
}