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Quantitative flow ratio will supplant wire-based physiological indices : pros and cons

Holm, Niels Ramsing ; Andersen, Birgitte Krogsgaard and Götberg, Matthias LU (2024) In EuroIntervention 20(19). p.1199-1201
Abstract

Quantitative flow ratio (QFR) represents a physiological index derived from angiography through three-dimensional (3D) quantitative coronary analysis. When compared to coronary angiography, QFR showed better performance both for guiding percutaneous coronary intervention (PCI) in case of intermediate coronary lesions and for optimising PCI results. In addition, QFR showed good diagnostic agreement with other established physiological indices, such as fractional flow reserve (FFR), with important practical advantages (e.g., fast and offline analysis). However, data on clinical outcomes in comparisons to wire-based physiological indices as well as validation studies in complex PCI and high-risk scenarios are still lacking. Further... (More)

Quantitative flow ratio (QFR) represents a physiological index derived from angiography through three-dimensional (3D) quantitative coronary analysis. When compared to coronary angiography, QFR showed better performance both for guiding percutaneous coronary intervention (PCI) in case of intermediate coronary lesions and for optimising PCI results. In addition, QFR showed good diagnostic agreement with other established physiological indices, such as fractional flow reserve (FFR), with important practical advantages (e.g., fast and offline analysis). However, data on clinical outcomes in comparisons to wire-based physiological indices as well as validation studies in complex PCI and high-risk scenarios are still lacking. Further research is needed to determine the exact field of application of QFR, and whether it can supplant wire-based physiological indices remains a matter of debate.

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Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
EuroIntervention
volume
20
issue
19
pages
1199 - 1201
publisher
Société Europa Edition
external identifiers
  • pmid:39374088
  • scopus:85205760694
ISSN
1774-024X
DOI
10.4244/EIJ-E-24-00031
language
English
LU publication?
yes
id
1bbf6323-dcd8-46b8-b66a-59613132f0b0
date added to LUP
2024-12-11 10:49:44
date last changed
2025-04-16 20:47:22
@article{1bbf6323-dcd8-46b8-b66a-59613132f0b0,
  abstract     = {{<p>Quantitative flow ratio (QFR) represents a physiological index derived from angiography through three-dimensional (3D) quantitative coronary analysis. When compared to coronary angiography, QFR showed better performance both for guiding percutaneous coronary intervention (PCI) in case of intermediate coronary lesions and for optimising PCI results. In addition, QFR showed good diagnostic agreement with other established physiological indices, such as fractional flow reserve (FFR), with important practical advantages (e.g., fast and offline analysis). However, data on clinical outcomes in comparisons to wire-based physiological indices as well as validation studies in complex PCI and high-risk scenarios are still lacking. Further research is needed to determine the exact field of application of QFR, and whether it can supplant wire-based physiological indices remains a matter of debate.</p>}},
  author       = {{Holm, Niels Ramsing and Andersen, Birgitte Krogsgaard and Götberg, Matthias}},
  issn         = {{1774-024X}},
  language     = {{eng}},
  month        = {{10}},
  number       = {{19}},
  pages        = {{1199--1201}},
  publisher    = {{Société Europa Edition}},
  series       = {{EuroIntervention}},
  title        = {{Quantitative flow ratio will supplant wire-based physiological indices : pros and cons}},
  url          = {{http://dx.doi.org/10.4244/EIJ-E-24-00031}},
  doi          = {{10.4244/EIJ-E-24-00031}},
  volume       = {{20}},
  year         = {{2024}},
}