Health-related quality of life as associated with asthma control, psychological status and insomnia
(2022) In Upsala Journal of Medical Sciences 127. p.1-9- Abstract
Background: Asthma is associated not only with lower health-related quality of life (HRQL) but also with psychological health and insomnia. The aim of this study was to investigate associations between HRQL, asthma symptoms, psychological status and insomnia in adults from three Nordic countries. Methods: This study comprised 2,270 subjects aged 29-55 from Sweden, Iceland and Norway. HRQL was measured with the 36-Item Short Form Health Survey (SF-36). The physical (PCS) and mental health (MCS) component scores were calculated with higher values, indicating better health status. Symptoms of depression and anxiety were measured using the Hospital Anxiety and Depression Scale (HADS). Insomnia was assessed with the Basic Nordic Sleep... (More)
Background: Asthma is associated not only with lower health-related quality of life (HRQL) but also with psychological health and insomnia. The aim of this study was to investigate associations between HRQL, asthma symptoms, psychological status and insomnia in adults from three Nordic countries. Methods: This study comprised 2,270 subjects aged 29-55 from Sweden, Iceland and Norway. HRQL was measured with the 36-Item Short Form Health Survey (SF-36). The physical (PCS) and mental health (MCS) component scores were calculated with higher values, indicating better health status. Symptoms of depression and anxiety were measured using the Hospital Anxiety and Depression Scale (HADS). Insomnia was assessed with the Basic Nordic Sleep Questionnaire. An asthma score consisting of a sum of the positive answers to five respiratory symptoms was used in the analysis. Spirometry and allergy tests were also performed. Results: High HADS and sleep disturbance scores were both related to a low PCS and MCS, respectively, after adjusting for confounders. High age and high body mass index (BMI) were associated with low scores on the PCS, whilst the opposite was found for the MCS. A higher asthma score was related to a low PCS. An interaction between the HADS and the asthma symptom score was observed for the PCS (P = 0.0002), where associations between psychological status and the PCS were more pronounced for individuals with more symptoms than for individuals without symptoms. Conclusions: In this study, we found that HRQL of life was independently related to the HADS, insomnia and asthma symptoms. Further prospective studies to identify the most efficient target for intervention in order to improve asthma control are needed.
(Less)
- author
- Rask-Andersen, Anna ; Leander, Mai ; Sundbom, Fredrik ; Lampa, Erik ; Oudin, Anna LU ; Leynaert, Bénédicte ; Svanes, Cecilie ; Gislason, Thorarinn ; Torén, Kjell and Janson, Christer
- organization
- publishing date
- 2022
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- anxiety, asthma symptoms, depression, Health-related quality of life, insomnia
- in
- Upsala Journal of Medical Sciences
- volume
- 127
- article number
- e8967
- pages
- 1 - 9
- publisher
- Taylor & Francis
- external identifiers
-
- scopus:85145345024
- pmid:36590755
- ISSN
- 0300-9734
- DOI
- 10.48101/ujms.v127.8967
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: © 2022 The Author(s). Published by Upsala Medical Society.
- id
- 1c0b3b5d-6283-4b79-bb91-d1f72a8443cb
- date added to LUP
- 2023-01-18 14:34:50
- date last changed
- 2024-05-30 14:24:11
@article{1c0b3b5d-6283-4b79-bb91-d1f72a8443cb,
abstract = {{<p>Background: Asthma is associated not only with lower health-related quality of life (HRQL) but also with psychological health and insomnia. The aim of this study was to investigate associations between HRQL, asthma symptoms, psychological status and insomnia in adults from three Nordic countries. Methods: This study comprised 2,270 subjects aged 29-55 from Sweden, Iceland and Norway. HRQL was measured with the 36-Item Short Form Health Survey (SF-36). The physical (PCS) and mental health (MCS) component scores were calculated with higher values, indicating better health status. Symptoms of depression and anxiety were measured using the Hospital Anxiety and Depression Scale (HADS). Insomnia was assessed with the Basic Nordic Sleep Questionnaire. An asthma score consisting of a sum of the positive answers to five respiratory symptoms was used in the analysis. Spirometry and allergy tests were also performed. Results: High HADS and sleep disturbance scores were both related to a low PCS and MCS, respectively, after adjusting for confounders. High age and high body mass index (BMI) were associated with low scores on the PCS, whilst the opposite was found for the MCS. A higher asthma score was related to a low PCS. An interaction between the HADS and the asthma symptom score was observed for the PCS (P = 0.0002), where associations between psychological status and the PCS were more pronounced for individuals with more symptoms than for individuals without symptoms. Conclusions: In this study, we found that HRQL of life was independently related to the HADS, insomnia and asthma symptoms. Further prospective studies to identify the most efficient target for intervention in order to improve asthma control are needed.</p>}},
author = {{Rask-Andersen, Anna and Leander, Mai and Sundbom, Fredrik and Lampa, Erik and Oudin, Anna and Leynaert, Bénédicte and Svanes, Cecilie and Gislason, Thorarinn and Torén, Kjell and Janson, Christer}},
issn = {{0300-9734}},
keywords = {{anxiety; asthma symptoms; depression; Health-related quality of life; insomnia}},
language = {{eng}},
pages = {{1--9}},
publisher = {{Taylor & Francis}},
series = {{Upsala Journal of Medical Sciences}},
title = {{Health-related quality of life as associated with asthma control, psychological status and insomnia}},
url = {{http://dx.doi.org/10.48101/ujms.v127.8967}},
doi = {{10.48101/ujms.v127.8967}},
volume = {{127}},
year = {{2022}},
}