Immunotherapy for Alzheimer disease
Gouras, Gunnar K. LU
(2009)
In mAbs
1(2).
p.112-114
- Abstract
Immunotherapy approaches for Alzheimer disease currently are among the leading therapeutic directions for the disease. Active and passive immunotherapy against the β-amyloid peptides that aggregate and accumulate in the brain of those afflicted by the disease have been shown by numerous groups to reduce plaque pathology and improve behavior in transgenic mouse models of the disease. Several ongoing immunotherapy clinical trials for Alzheimer disease are in progress. The background and ongoing challenges for these immunological approaches for the treatment of Alzheimer disease are discussed.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1c2728cc-4e58-4976-9982-d46c212f3019
- author
- Gouras, Gunnar K.
LU
- publishing date
- 2009-03-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Alzheimer disease, Amyloid, Immunotherapy, Tau, Vaccine
- in
- mAbs
- volume
- 1
- issue
- 2
- pages
- 3 pages
- publisher
- Taylor & Francis
- external identifiers
-
- scopus:77953663334
- pmid:20061820
- ISSN
- 1942-0862
- DOI
- 10.4161/mabs.1.2.7829
- language
- English
- LU publication?
- no
- id
- 1c2728cc-4e58-4976-9982-d46c212f3019
- date added to LUP
- 2020-02-20 14:41:50
- date last changed
- 2024-04-03 03:20:02
@article{1c2728cc-4e58-4976-9982-d46c212f3019,
abstract = {{<p>Immunotherapy approaches for Alzheimer disease currently are among the leading therapeutic directions for the disease. Active and passive immunotherapy against the β-amyloid peptides that aggregate and accumulate in the brain of those afflicted by the disease have been shown by numerous groups to reduce plaque pathology and improve behavior in transgenic mouse models of the disease. Several ongoing immunotherapy clinical trials for Alzheimer disease are in progress. The background and ongoing challenges for these immunological approaches for the treatment of Alzheimer disease are discussed.</p>}},
author = {{Gouras, Gunnar K.}},
issn = {{1942-0862}},
keywords = {{Alzheimer disease; Amyloid; Immunotherapy; Tau; Vaccine}},
language = {{eng}},
month = {{03}},
number = {{2}},
pages = {{112--114}},
publisher = {{Taylor & Francis}},
series = {{mAbs}},
title = {{Immunotherapy for Alzheimer disease}},
url = {{http://dx.doi.org/10.4161/mabs.1.2.7829}},
doi = {{10.4161/mabs.1.2.7829}},
volume = {{1}},
year = {{2009}},
}