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Cystatin C as a Multifaceted Biomarker in Kidney Disease and Its Role in Defining "Shrunken Pore Syndrome"

Grubb, A. LU (2017) In Biomarkers of Kidney Disease p.225-240
Abstract

Cystatin C, a basic nonglycosylated 13.3 kDa protein comprising a single polypeptide chain of 120 amino acid residues, is produced at a stable rate from a housekeeping gene in all nucleated cells and eliminated from the circulation by free filtration through the glomerular membranes as described in the first edition of "Biomarkers of Kidney Disease." This discourse will report some of the progress in the use of cystatin C as a multifaceted marker of kidney disease, which has occurred since then, including its role in identifying the novel syndrome called "Shrunken Pore Syndrome."

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author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Biomarker, Creatinine, Cystatin C, GFR-estimating equations, Internal and external validation, Renal reserve, Shrunken Pore Syndrome
in
Biomarkers of Kidney Disease
editor
Edelstein, C.L. and
pages
16 pages
publisher
Elsevier Inc.
external identifiers
  • scopus:85010190522
ISBN
9780128030141
DOI
10.1016/B978-0-12-803014-1.00005-4
language
English
LU publication?
yes
id
1c32d304-1a34-4770-836b-ebf87ecea8aa
date added to LUP
2017-02-06 11:16:31
date last changed
2018-01-07 11:48:46
@inbook{1c32d304-1a34-4770-836b-ebf87ecea8aa,
  abstract     = {<p>Cystatin C, a basic nonglycosylated 13.3 kDa protein comprising a single polypeptide chain of 120 amino acid residues, is produced at a stable rate from a housekeeping gene in all nucleated cells and eliminated from the circulation by free filtration through the glomerular membranes as described in the first edition of "Biomarkers of Kidney Disease." This discourse will report some of the progress in the use of cystatin C as a multifaceted marker of kidney disease, which has occurred since then, including its role in identifying the novel syndrome called "Shrunken Pore Syndrome."</p>},
  author       = {Grubb, A.},
  editor       = {Edelstein, C.L.},
  isbn         = {9780128030141},
  keyword      = {Biomarker,Creatinine,Cystatin C,GFR-estimating equations,Internal and external validation,Renal reserve,Shrunken Pore Syndrome},
  language     = {eng},
  pages        = {225--240},
  publisher    = {Elsevier Inc.},
  series       = {Biomarkers of Kidney Disease},
  title        = {Cystatin C as a Multifaceted Biomarker in Kidney Disease and Its Role in Defining "Shrunken Pore Syndrome"},
  url          = {http://dx.doi.org/10.1016/B978-0-12-803014-1.00005-4},
  year         = {2017},
}