Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

The dual photopeak-area method applied to scintillation camera measurements of effective depth and activity of in vivo 123I-distributions

Strand, Sven Erik LU and Persson, Bertil R.R. LU orcid (1977) In European Journal Of Nuclear Medicine 2(2). p.121-128
Abstract

Attenuation curves and photopeak ratios of 159 keV and 28 keV phtons emitted in the decay of 123I have been studied using a scintillation camera equipped with an extra ADC for recording the pulse height distribution of the energy signal. Cavities of various sizes containing 123I-solution were placed at different depths in a water phantom in order to vary the effective depth, i.e., the thickness of attenuating material above the cavity plus the distance to the centre of activity in the cavity. The centre of activity varies with the distribution of activity in the cavity, size of cavity, and the effective attenuation coefficient derived from the attenuation curves. From the photopeak ratio an average effective depth... (More)

Attenuation curves and photopeak ratios of 159 keV and 28 keV phtons emitted in the decay of 123I have been studied using a scintillation camera equipped with an extra ADC for recording the pulse height distribution of the energy signal. Cavities of various sizes containing 123I-solution were placed at different depths in a water phantom in order to vary the effective depth, i.e., the thickness of attenuating material above the cavity plus the distance to the centre of activity in the cavity. The centre of activity varies with the distribution of activity in the cavity, size of cavity, and the effective attenuation coefficient derived from the attenuation curves. From the photopeak ratio an average effective depth is determined which can be used for calculating the attenuation correction factor. The dual photopeak ratio has been used in clinical evaluation of thyroid 123I uptake measurements where effective depths ranging from 21 to 43 mm were obtained for the activity in the thyroid. Applications of the photopeak ratio method for renography with 123I-hippuran and blood flow studies using 133Xe or 127Xe and studies with many other radionuclides are also discussed.

(Less)
Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Contribution to journal
publication status
published
in
European Journal Of Nuclear Medicine
volume
2
issue
2
pages
8 pages
publisher
Springer
external identifiers
  • scopus:0017646215
  • pmid:891557
ISSN
0340-6997
DOI
10.1007/BF00253685
language
English
LU publication?
yes
id
1ca85b44-5276-4735-87d6-aef3599dd556
date added to LUP
2020-08-30 21:00:09
date last changed
2024-01-17 12:17:31
@article{1ca85b44-5276-4735-87d6-aef3599dd556,
  abstract     = {{<p>Attenuation curves and photopeak ratios of 159 keV and 28 keV phtons emitted in the decay of <sup>123</sup>I have been studied using a scintillation camera equipped with an extra ADC for recording the pulse height distribution of the energy signal. Cavities of various sizes containing <sup>123</sup>I-solution were placed at different depths in a water phantom in order to vary the effective depth, i.e., the thickness of attenuating material above the cavity plus the distance to the centre of activity in the cavity. The centre of activity varies with the distribution of activity in the cavity, size of cavity, and the effective attenuation coefficient derived from the attenuation curves. From the photopeak ratio an average effective depth is determined which can be used for calculating the attenuation correction factor. The dual photopeak ratio has been used in clinical evaluation of thyroid <sup>123</sup>I uptake measurements where effective depths ranging from 21 to 43 mm were obtained for the activity in the thyroid. Applications of the photopeak ratio method for renography with <sup>123</sup>I-hippuran and blood flow studies using <sup>133</sup>Xe or <sup>127</sup>Xe and studies with many other radionuclides are also discussed.</p>}},
  author       = {{Strand, Sven Erik and Persson, Bertil R.R.}},
  issn         = {{0340-6997}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{2}},
  pages        = {{121--128}},
  publisher    = {{Springer}},
  series       = {{European Journal Of Nuclear Medicine}},
  title        = {{The dual photopeak-area method applied to scintillation camera measurements of effective depth and activity of in vivo <sup>123</sup>I-distributions}},
  url          = {{http://dx.doi.org/10.1007/BF00253685}},
  doi          = {{10.1007/BF00253685}},
  volume       = {{2}},
  year         = {{1977}},
}