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Motion-corrected brain MRI at ultralow field (64 mT)

Brackenier, Yannick ; Teixeira, Rui Pedro ; Cordero-Grande, Lucilio ; Ljungberg, Emil LU orcid ; Bourke, Niall J. ; Arichi, Tomoki ; Deoni, Sean ; Williams, Steve C.R. and Hajnal, Joseph V. (2025) In Magnetic Resonance in Medicine 94(2). p.825-834
Abstract

Purpose: The study investigates the feasibility of applying a retrospective motion-correction technique to ultralow-field (ULF) MRI data to improve reconstructed image quality when there is patient motion, which is likely to be a critical challenge in portable, point-of-care imaging. Theory & Methods: The study tests alignedSENSE, an iterative motion correction and reconstruction method with SENSE, for ULF MRI, with additional corrections to estimate and correct within-scan phase variations. The method was applied to in vivo brain volumetric data acquired from five healthy volunteers using a 64 mT portable MRI scanner. The volunteers underwent different motion types and levels, with corrections evaluated using both visual and... (More)

Purpose: The study investigates the feasibility of applying a retrospective motion-correction technique to ultralow-field (ULF) MRI data to improve reconstructed image quality when there is patient motion, which is likely to be a critical challenge in portable, point-of-care imaging. Theory & Methods: The study tests alignedSENSE, an iterative motion correction and reconstruction method with SENSE, for ULF MRI, with additional corrections to estimate and correct within-scan phase variations. The method was applied to in vivo brain volumetric data acquired from five healthy volunteers using a 64 mT portable MRI scanner. The volunteers underwent different motion types and levels, with corrections evaluated using both visual and quantitative metrics. Results: Motion correction, particularly when within-scan phase variations are also accounted for, showed clear improvements in image quality. Without making any assumptions about the origin of these phase variations, incorporating them into the signal model and jointly estimating with the image/motion parameters increases the data consistency. This improves the image quality and motion parameters across various levels of induced motion. Quantitative analysis confirmed that the combined motion and phase corrections outperformed conventional parallel imaging reconstruction, although extreme motion cases still pose challenges. Conclusion: The study demonstrates that alignedSENSE motion-correction techniques can be effectively applied to ULF MRI systems. The results suggest that these techniques can substantially enhance image quality without increasing scan time, which could make ULF MRI more clinically viable for point-of-care deployment.

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author
; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
brain, motion correction, reconstruction, ultralow field
in
Magnetic Resonance in Medicine
volume
94
issue
2
pages
10 pages
publisher
John Wiley & Sons Inc.
external identifiers
  • pmid:40152515
  • scopus:105001820959
ISSN
0740-3194
DOI
10.1002/mrm.30506
language
English
LU publication?
yes
id
1da14c01-7cec-4d33-8702-610a313c2d48
date added to LUP
2025-09-03 10:39:07
date last changed
2025-09-04 03:33:33
@article{1da14c01-7cec-4d33-8702-610a313c2d48,
  abstract     = {{<p>Purpose: The study investigates the feasibility of applying a retrospective motion-correction technique to ultralow-field (ULF) MRI data to improve reconstructed image quality when there is patient motion, which is likely to be a critical challenge in portable, point-of-care imaging. Theory &amp; Methods: The study tests alignedSENSE, an iterative motion correction and reconstruction method with SENSE, for ULF MRI, with additional corrections to estimate and correct within-scan phase variations. The method was applied to in vivo brain volumetric data acquired from five healthy volunteers using a 64 mT portable MRI scanner. The volunteers underwent different motion types and levels, with corrections evaluated using both visual and quantitative metrics. Results: Motion correction, particularly when within-scan phase variations are also accounted for, showed clear improvements in image quality. Without making any assumptions about the origin of these phase variations, incorporating them into the signal model and jointly estimating with the image/motion parameters increases the data consistency. This improves the image quality and motion parameters across various levels of induced motion. Quantitative analysis confirmed that the combined motion and phase corrections outperformed conventional parallel imaging reconstruction, although extreme motion cases still pose challenges. Conclusion: The study demonstrates that alignedSENSE motion-correction techniques can be effectively applied to ULF MRI systems. The results suggest that these techniques can substantially enhance image quality without increasing scan time, which could make ULF MRI more clinically viable for point-of-care deployment.</p>}},
  author       = {{Brackenier, Yannick and Teixeira, Rui Pedro and Cordero-Grande, Lucilio and Ljungberg, Emil and Bourke, Niall J. and Arichi, Tomoki and Deoni, Sean and Williams, Steve C.R. and Hajnal, Joseph V.}},
  issn         = {{0740-3194}},
  keywords     = {{brain; motion correction; reconstruction; ultralow field}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{825--834}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Magnetic Resonance in Medicine}},
  title        = {{Motion-corrected brain MRI at ultralow field (64 mT)}},
  url          = {{http://dx.doi.org/10.1002/mrm.30506}},
  doi          = {{10.1002/mrm.30506}},
  volume       = {{94}},
  year         = {{2025}},
}