Mycoplasma pneumonia with severe cold agglutinin hemolysis, thrombocytosis, leukemoid reaction and acute renal failure
(2023) In IDCases 31.- Abstract
Mycoplasma pneumoniae (M. pneumoniae) is a common cause of community acquired pneumonia and although most cases are mild, complications sometimes occur. Cold agglutinin hemolysis is a known complication of M. pneumoniae infection, and usually presents as a mild and transient hemolysis. Here we present a case of infection with M. pneumoniae in a 64-year-old male that caused life threatening hemolysis that required multiple blood transfusions. The patient also presented with acute kidney failure and a marked leukemoid reaction and thrombocytosis. This is a very rare combination of symptoms that could have led the clinicians to suspect a more virulent etiology than M. pneumoniae, thereby delaying adequate antibiotic treatment.
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https://lup.lub.lu.se/record/1e4a106d-e5d6-481d-af44-082cd785af2f
- author
- Widén, Johan LU ; Jönsson, Göran LU and Karlsson, Ulf LU
- organization
- publishing date
- 2023-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Acute kidney failure, Cold-agglutinin hemolysis, Corticosteroids, Leukemoid reaction, Mycoplasma pneumoniae
- in
- IDCases
- volume
- 31
- article number
- e01689
- publisher
- Elsevier
- external identifiers
-
- pmid:36687368
- scopus:85146352639
- ISSN
- 2214-2509
- DOI
- 10.1016/j.idcr.2023.e01689
- language
- English
- LU publication?
- yes
- id
- 1e4a106d-e5d6-481d-af44-082cd785af2f
- date added to LUP
- 2023-02-15 10:36:19
- date last changed
- 2024-09-06 08:07:07
@article{1e4a106d-e5d6-481d-af44-082cd785af2f, abstract = {{<p>Mycoplasma pneumoniae (M. pneumoniae) is a common cause of community acquired pneumonia and although most cases are mild, complications sometimes occur. Cold agglutinin hemolysis is a known complication of M. pneumoniae infection, and usually presents as a mild and transient hemolysis. Here we present a case of infection with M. pneumoniae in a 64-year-old male that caused life threatening hemolysis that required multiple blood transfusions. The patient also presented with acute kidney failure and a marked leukemoid reaction and thrombocytosis. This is a very rare combination of symptoms that could have led the clinicians to suspect a more virulent etiology than M. pneumoniae, thereby delaying adequate antibiotic treatment.</p>}}, author = {{Widén, Johan and Jönsson, Göran and Karlsson, Ulf}}, issn = {{2214-2509}}, keywords = {{Acute kidney failure; Cold-agglutinin hemolysis; Corticosteroids; Leukemoid reaction; Mycoplasma pneumoniae}}, language = {{eng}}, publisher = {{Elsevier}}, series = {{IDCases}}, title = {{Mycoplasma pneumonia with severe cold agglutinin hemolysis, thrombocytosis, leukemoid reaction and acute renal failure}}, url = {{http://dx.doi.org/10.1016/j.idcr.2023.e01689}}, doi = {{10.1016/j.idcr.2023.e01689}}, volume = {{31}}, year = {{2023}}, }