Intravascular ultrasound assessed incomplete stent apposition and stent fracture in stent thrombosis after bare metal versus drug-eluting stent treatment the Nordic Intravascular Ultrasound Study (NIVUS)
(2013) In International Journal of Cardiology 168(2). p.1010-1016- Abstract
- Background: This prospective multicenter registry used intravascular ultrasound (IVUS) in patients with definite stent thrombosis (ST) to compare rates of incomplete stent apposition (ISA), stent fracture and stent expansion in patients treated with drug-eluting (DES) versus bare metal (BMS) stents. ST is a rare, but potential life threatening event after coronary stent implantation. The etiology seems to be multifactorial. Methods: 124 patients with definite ST were assessed by IVUS during the acute ST event. The study was conducted in 15 high-volume percutaneous coronary intervention -centers in the Nordic-Baltic countries. Results: In early or late ST there were no differences in ISA between DES and BMS. In very late ST, ISA was a more... (More)
- Background: This prospective multicenter registry used intravascular ultrasound (IVUS) in patients with definite stent thrombosis (ST) to compare rates of incomplete stent apposition (ISA), stent fracture and stent expansion in patients treated with drug-eluting (DES) versus bare metal (BMS) stents. ST is a rare, but potential life threatening event after coronary stent implantation. The etiology seems to be multifactorial. Methods: 124 patients with definite ST were assessed by IVUS during the acute ST event. The study was conducted in 15 high-volume percutaneous coronary intervention -centers in the Nordic-Baltic countries. Results: In early or late ST there were no differences in ISA between DES and BMS. In very late ST, ISA was a more frequent finding in DES than in BMS (52% vs. 16%; p=0.005) and the maximum ISA area was larger in DES compared to BMS(1.1 +/- 2.3 mm(2) vs. 0.1 +/- 0.5 mm(2); p=0.004). Further, ISA was more prevalent in sirolimus-eluting than in paclitaxel-eluting stents (58% vs. 37%; p-0.02). Stent fractures were found both in DES (16%) and BMS (24%); p=0.28, and not related to time of stent thrombosis occurrence. For stents with nominal diameters >= 2.75 mm, 38% of the DES and 22% of the BMS had a minimum stent area of less than 5 mm(2); p=0.14. Conclusions: Very late stent thrombosis was more prevalent and associated with more extensive ISA in DES than in BMS treated patients. Stent fracture was a common finding in ST after DES and BMS implantation. (C) 2012 Elsevier Ireland Ltd. All rights reserved. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4166498
- author
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Stent thrombosis, Drug eluting stents, Bare metal stents, Intravascular, ultrasound
- in
- International Journal of Cardiology
- volume
- 168
- issue
- 2
- pages
- 1010 - 1016
- publisher
- Elsevier
- external identifiers
-
- wos:000325412800079
- scopus:84885318016
- pmid:23164593
- ISSN
- 0167-5273
- DOI
- 10.1016/j.ijcard.2012.10.033
- language
- English
- LU publication?
- yes
- id
- 1e7fd663-bdbf-470d-9fb7-034fe233000d (old id 4166498)
- date added to LUP
- 2016-04-01 10:06:16
- date last changed
- 2022-01-25 19:45:48
@article{1e7fd663-bdbf-470d-9fb7-034fe233000d,
abstract = {{Background: This prospective multicenter registry used intravascular ultrasound (IVUS) in patients with definite stent thrombosis (ST) to compare rates of incomplete stent apposition (ISA), stent fracture and stent expansion in patients treated with drug-eluting (DES) versus bare metal (BMS) stents. ST is a rare, but potential life threatening event after coronary stent implantation. The etiology seems to be multifactorial. Methods: 124 patients with definite ST were assessed by IVUS during the acute ST event. The study was conducted in 15 high-volume percutaneous coronary intervention -centers in the Nordic-Baltic countries. Results: In early or late ST there were no differences in ISA between DES and BMS. In very late ST, ISA was a more frequent finding in DES than in BMS (52% vs. 16%; p=0.005) and the maximum ISA area was larger in DES compared to BMS(1.1 +/- 2.3 mm(2) vs. 0.1 +/- 0.5 mm(2); p=0.004). Further, ISA was more prevalent in sirolimus-eluting than in paclitaxel-eluting stents (58% vs. 37%; p-0.02). Stent fractures were found both in DES (16%) and BMS (24%); p=0.28, and not related to time of stent thrombosis occurrence. For stents with nominal diameters >= 2.75 mm, 38% of the DES and 22% of the BMS had a minimum stent area of less than 5 mm(2); p=0.14. Conclusions: Very late stent thrombosis was more prevalent and associated with more extensive ISA in DES than in BMS treated patients. Stent fracture was a common finding in ST after DES and BMS implantation. (C) 2012 Elsevier Ireland Ltd. All rights reserved.}},
author = {{Kosonen, Petteri and Vikman, Saila and Jensen, Lisette Okkels and Lassen, Jens Flensted and Harnek, Jan and Olivecrona, Göran and Erglis, Andrejs and Fossum, Eigil and Niemela, Matti and Kervinen, Kari and Ylitalo, Antti and Pietila, Mikko and Aaroe, Jens and Kellerth, Thomas and Saunamaki, Kari and Thayssen, Per and Hellsten, Lars and Thuesen, Leif and Niemela, Kari}},
issn = {{0167-5273}},
keywords = {{Stent thrombosis; Drug eluting stents; Bare metal stents; Intravascular; ultrasound}},
language = {{eng}},
number = {{2}},
pages = {{1010--1016}},
publisher = {{Elsevier}},
series = {{International Journal of Cardiology}},
title = {{Intravascular ultrasound assessed incomplete stent apposition and stent fracture in stent thrombosis after bare metal versus drug-eluting stent treatment the Nordic Intravascular Ultrasound Study (NIVUS)}},
url = {{http://dx.doi.org/10.1016/j.ijcard.2012.10.033}},
doi = {{10.1016/j.ijcard.2012.10.033}},
volume = {{168}},
year = {{2013}},
}