The lectin complement pathway serine proteases (MASPs) represent a possible crossroad between the coagulation and complement systems in thromboinflammation.
(2016) In Journal of Thrombosis and Haemostasis 14(3). p.531-545- Abstract
- The activated forms of the complement lectin pathway (LP) proteases MASP-1 and -2 are able to cleave the coagulation factors prothrombin, fibrinogen, factor XIII and TAFI in vitro. In vivo studies also show that MASP-1 is involved in thrombogenesis, OBJECTIVES: To clarify the not yet identified mechanisms involved in triggering activation of the LP during thrombotic reactions.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8234312
- author
- organization
- publishing date
- 2016
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Thrombosis and Haemostasis
- volume
- 14
- issue
- 3
- pages
- 531 - 545
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:26614707
- scopus:84960100143
- wos:000372525100015
- pmid:26614707
- ISSN
- 1538-7933
- DOI
- 10.1111/jth.13208
- language
- English
- LU publication?
- yes
- id
- 1ec9af7f-f899-4a2f-84cc-24c19d7291a8 (old id 8234312)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26614707?dopt=Abstract
- date added to LUP
- 2016-04-04 08:41:44
- date last changed
- 2022-04-23 17:48:34
@article{1ec9af7f-f899-4a2f-84cc-24c19d7291a8, abstract = {{The activated forms of the complement lectin pathway (LP) proteases MASP-1 and -2 are able to cleave the coagulation factors prothrombin, fibrinogen, factor XIII and TAFI in vitro. In vivo studies also show that MASP-1 is involved in thrombogenesis, OBJECTIVES: To clarify the not yet identified mechanisms involved in triggering activation of the LP during thrombotic reactions.}}, author = {{Kozarcanin, Huda and Lood, Christian and Munthe-Fog, Lea and Sandholm, Kerstin and Hamad, Osama A and Bengtsson, Anders and Skjoedt, Mikkel-Ole and Huber-Lang, Markus and Garred, Peter and Ekdahl, Kristina N and Nilsson, Bo}}, issn = {{1538-7933}}, language = {{eng}}, number = {{3}}, pages = {{531--545}}, publisher = {{Wiley-Blackwell}}, series = {{Journal of Thrombosis and Haemostasis}}, title = {{The lectin complement pathway serine proteases (MASPs) represent a possible crossroad between the coagulation and complement systems in thromboinflammation.}}, url = {{http://dx.doi.org/10.1111/jth.13208}}, doi = {{10.1111/jth.13208}}, volume = {{14}}, year = {{2016}}, }