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Estimation of HIV incidence and its trend in three key populations in Iran

Sharifi, Hamid ; Mirzazadeh, Ali ; Shokoohi, Mostafa ; Karamouzian, Mohammad ; Khajehkazemi, Razieh ; Navadeh, Soodabeh ; Fahimfar, Noushin ; Danesh, Ahmad ; Osooli, Mehdi LU orcid and McFarland, Willi , et al. (2018) In PLoS ONE 13(11).
Abstract

In Iran, People Who Inject Drugs (PWID), Female Sex Workers (FSW), and prisoners are the main key populations at risk of HIV infection. This study aimed to evaluate the trend of HIV incidence among PWID, FSW and prisoners as an impact measure of HIV harm reduction and prevention efforts in Iran. Data were obtained from the two rounds of national bio-behavioral surveillance surveys among FSW (2010 (n = 872), 2015 (n = 1339)), PWID (2010 (n = 2417), 2014 (n = 2307)), and prisoners (2009 (n = 4536), 2013 (n = 5390)) through facility-based (FSW and PWID surveys) and cluster sampling (prisoner surveys). Time-at-risk was calculated assuming the age at first sex or drug injection as the beginning of the at-risk period and the age at the time... (More)

In Iran, People Who Inject Drugs (PWID), Female Sex Workers (FSW), and prisoners are the main key populations at risk of HIV infection. This study aimed to evaluate the trend of HIV incidence among PWID, FSW and prisoners as an impact measure of HIV harm reduction and prevention efforts in Iran. Data were obtained from the two rounds of national bio-behavioral surveillance surveys among FSW (2010 (n = 872), 2015 (n = 1339)), PWID (2010 (n = 2417), 2014 (n = 2307)), and prisoners (2009 (n = 4536), 2013 (n = 5390)) through facility-based (FSW and PWID surveys) and cluster sampling (prisoner surveys). Time-at-risk was calculated assuming the age at first sex or drug injection as the beginning of the at-risk period and the age at the time of the interview or date when they received a positive HIV test result as the end of this period, adjusted for interval censoring. HIV incidence among PWID in 2014 was 5.39 (95% CI 4.71, 6.16) per 1,000 person-years (PY), significantly lower than in 2009 (17.07, 95% CI 15.34, 19.34). Similarly, HIV incidence was 1.12 (95% CI 0.77, 1.64) per 1,000 PY among FSW in 2015, a significant drop from 2010 (2.38, 95% CI 1.66, 3.40). Also, HIV incidence decreased among prisoners from 1.34 (95% CI: 1.08, 1.67) in 2009 to 0.49 (95% CI: 0.39, 0.61) per 1,000 PY in 2013. Our findings suggest that after an increase in the 2000s, the HIV incidence may have been decreased and stabilized among key populations in Iran.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
13
issue
11
article number
e0207681
publisher
Public Library of Science (PLoS)
external identifiers
  • scopus:85057445755
  • pmid:30496204
ISSN
1932-6203
DOI
10.1371/journal.pone.0207681
language
English
LU publication?
yes
id
1f27e15d-a30f-48cb-9be9-ecdd3c25e4ca
date added to LUP
2018-12-10 09:44:30
date last changed
2024-05-27 23:30:38
@article{1f27e15d-a30f-48cb-9be9-ecdd3c25e4ca,
  abstract     = {{<p>In Iran, People Who Inject Drugs (PWID), Female Sex Workers (FSW), and prisoners are the main key populations at risk of HIV infection. This study aimed to evaluate the trend of HIV incidence among PWID, FSW and prisoners as an impact measure of HIV harm reduction and prevention efforts in Iran. Data were obtained from the two rounds of national bio-behavioral surveillance surveys among FSW (2010 (n = 872), 2015 (n = 1339)), PWID (2010 (n = 2417), 2014 (n = 2307)), and prisoners (2009 (n = 4536), 2013 (n = 5390)) through facility-based (FSW and PWID surveys) and cluster sampling (prisoner surveys). Time-at-risk was calculated assuming the age at first sex or drug injection as the beginning of the at-risk period and the age at the time of the interview or date when they received a positive HIV test result as the end of this period, adjusted for interval censoring. HIV incidence among PWID in 2014 was 5.39 (95% CI 4.71, 6.16) per 1,000 person-years (PY), significantly lower than in 2009 (17.07, 95% CI 15.34, 19.34). Similarly, HIV incidence was 1.12 (95% CI 0.77, 1.64) per 1,000 PY among FSW in 2015, a significant drop from 2010 (2.38, 95% CI 1.66, 3.40). Also, HIV incidence decreased among prisoners from 1.34 (95% CI: 1.08, 1.67) in 2009 to 0.49 (95% CI: 0.39, 0.61) per 1,000 PY in 2013. Our findings suggest that after an increase in the 2000s, the HIV incidence may have been decreased and stabilized among key populations in Iran.</p>}},
  author       = {{Sharifi, Hamid and Mirzazadeh, Ali and Shokoohi, Mostafa and Karamouzian, Mohammad and Khajehkazemi, Razieh and Navadeh, Soodabeh and Fahimfar, Noushin and Danesh, Ahmad and Osooli, Mehdi and McFarland, Willi and Gouya, Mohammad Mehdi and Haghdoost, Ali Akbar}},
  issn         = {{1932-6203}},
  language     = {{eng}},
  month        = {{11}},
  number       = {{11}},
  publisher    = {{Public Library of Science (PLoS)}},
  series       = {{PLoS ONE}},
  title        = {{Estimation of HIV incidence and its trend in three key populations in Iran}},
  url          = {{http://dx.doi.org/10.1371/journal.pone.0207681}},
  doi          = {{10.1371/journal.pone.0207681}},
  volume       = {{13}},
  year         = {{2018}},
}