Patch testing with a new composition of mercapto mix : A multicentre study by the Swedish contact dermatitis research group
(2019) In Acta Dermato-Venereologica 99(11). p.960-963- Abstract
This study investigated whether more patients with contact allergies were detected by patch testing with mercapto mix with a higher concentration of 2-mercaptobenzothiazolinone (MBT) than the commonly used mercapto mix. A total of 3,143 dermatitis patients in 5 Swedish dermatology departments were patch- tested with 3 mercapto test preparations: MBT 2.0% petrolatum (pet.); mercapto mix 2.0% pet.; and mercapto mix 3.5% pet. Positive reactions to these mercapto mixes varied between 0–0.50%, 0–0.93%, and 0–1.4%, respectively, in the 5 centres. Numerically, mercapto mix 3.5% pet. detected all positive patients and more patch-test positive patients than did the 2 other substances, but the difference was not statistically significant. The... (More)
This study investigated whether more patients with contact allergies were detected by patch testing with mercapto mix with a higher concentration of 2-mercaptobenzothiazolinone (MBT) than the commonly used mercapto mix. A total of 3,143 dermatitis patients in 5 Swedish dermatology departments were patch- tested with 3 mercapto test preparations: MBT 2.0% petrolatum (pet.); mercapto mix 2.0% pet.; and mercapto mix 3.5% pet. Positive reactions to these mercapto mixes varied between 0–0.50%, 0–0.93%, and 0–1.4%, respectively, in the 5 centres. Numerically, mercapto mix 3.5% pet. detected all positive patients and more patch-test positive patients than did the 2 other substances, but the difference was not statistically significant. The authors recommend replacing mercapto mix 2.0% pet. in the Swedish baseline series with mercapto mix 3.5% pet., since the latter also detected those patients who would have been missed because MBT 2.0% is not included in the Swedish baseline series.
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- author
- Engfeldt, Malin LU ; Isaksson, Marléne LU ; Glas, Bo ; Hagvall, Lina ; Löfnertz Petersson, Anna ; Matura, Mihaly ; Stenberg, Berndt ; Svedman, Cecilia LU and Bruze, Magnus LU
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- 2-mercaptobenzothiazole, Allergic contact dermatitis, Contact allergy, Delayed hypersensitivity, Mercapto mix, Rubber
- in
- Acta Dermato-Venereologica
- volume
- 99
- issue
- 11
- pages
- 4 pages
- publisher
- Medical Journals Limited
- external identifiers
-
- pmid:31240321
- scopus:85073461735
- ISSN
- 0001-5555
- DOI
- 10.2340/00015555-3249
- language
- English
- LU publication?
- yes
- id
- 1f2dc0e1-8f2e-4c4d-9820-05f897a978ea
- date added to LUP
- 2019-10-28 15:02:41
- date last changed
- 2024-05-29 02:49:43
@article{1f2dc0e1-8f2e-4c4d-9820-05f897a978ea, abstract = {{<p>This study investigated whether more patients with contact allergies were detected by patch testing with mercapto mix with a higher concentration of 2-mercaptobenzothiazolinone (MBT) than the commonly used mercapto mix. A total of 3,143 dermatitis patients in 5 Swedish dermatology departments were patch- tested with 3 mercapto test preparations: MBT 2.0% petrolatum (pet.); mercapto mix 2.0% pet.; and mercapto mix 3.5% pet. Positive reactions to these mercapto mixes varied between 0–0.50%, 0–0.93%, and 0–1.4%, respectively, in the 5 centres. Numerically, mercapto mix 3.5% pet. detected all positive patients and more patch-test positive patients than did the 2 other substances, but the difference was not statistically significant. The authors recommend replacing mercapto mix 2.0% pet. in the Swedish baseline series with mercapto mix 3.5% pet., since the latter also detected those patients who would have been missed because MBT 2.0% is not included in the Swedish baseline series.</p>}}, author = {{Engfeldt, Malin and Isaksson, Marléne and Glas, Bo and Hagvall, Lina and Löfnertz Petersson, Anna and Matura, Mihaly and Stenberg, Berndt and Svedman, Cecilia and Bruze, Magnus}}, issn = {{0001-5555}}, keywords = {{2-mercaptobenzothiazole; Allergic contact dermatitis; Contact allergy; Delayed hypersensitivity; Mercapto mix; Rubber}}, language = {{eng}}, number = {{11}}, pages = {{960--963}}, publisher = {{Medical Journals Limited}}, series = {{Acta Dermato-Venereologica}}, title = {{Patch testing with a new composition of mercapto mix : A multicentre study by the Swedish contact dermatitis research group}}, url = {{http://dx.doi.org/10.2340/00015555-3249}}, doi = {{10.2340/00015555-3249}}, volume = {{99}}, year = {{2019}}, }