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Substance P and vasoactive intestinal peptide in bullous and inflammatory skin disease.

Wallengren, Joanna LU orcid ; Ekman, Rolf and Möller, Halvor LU (1986) In Acta Dermato-Venereologica 66(1). p.23-28
Abstract
Immunoreactivity (IR) of substance P (SP) and Vasoactive Intestinal Peptide (VIP) were determined by radioimmunoassay in serum of 56 patients with inflammatory skin diseases, in blister fluid of 40 patients with spontaneous blisters and 31 subjects with induced skin blisters. Serum concentrations of SP-IR and VIP-IR were mostly low or non-detectable. Spontaneous blisters contained high amounts of SP-IR, particularly in bullous pemphigoid and in some inflammatory dermatoses, while VIP-IR levels usually were low. Suction blisters from inflamed but not from normal skin often contained SP-IR but more seldom VIP-IR.
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Dermato-Venereologica
volume
66
issue
1
pages
23 - 28
publisher
Medical Journals Limited
external identifiers
  • pmid:2424210
  • scopus:0022645274
ISSN
1651-2057
language
English
LU publication?
yes
id
1f666f15-95d1-4a51-97c8-53d59381c4f3
date added to LUP
2019-07-25 15:24:01
date last changed
2021-10-23 04:03:16
@article{1f666f15-95d1-4a51-97c8-53d59381c4f3,
  abstract     = {{Immunoreactivity (IR) of substance P (SP) and Vasoactive Intestinal Peptide (VIP) were determined by radioimmunoassay in serum of 56 patients with inflammatory skin diseases, in blister fluid of 40 patients with spontaneous blisters and 31 subjects with induced skin blisters. Serum concentrations of SP-IR and VIP-IR were mostly low or non-detectable. Spontaneous blisters contained high amounts of SP-IR, particularly in bullous pemphigoid and in some inflammatory dermatoses, while VIP-IR levels usually were low. Suction blisters from inflamed but not from normal skin often contained SP-IR but more seldom VIP-IR.}},
  author       = {{Wallengren, Joanna and Ekman, Rolf and Möller, Halvor}},
  issn         = {{1651-2057}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{23--28}},
  publisher    = {{Medical Journals Limited}},
  series       = {{Acta Dermato-Venereologica}},
  title        = {{Substance P and vasoactive intestinal peptide in bullous and inflammatory skin disease.}},
  volume       = {{66}},
  year         = {{1986}},
}