Swedish national guideline for prevention and treatment of neonatal hypoglycaemia in newborn infants with gestational age ≥35 weeks
Wackernagel, Dirk ; Gustafsson, Anna ; Edstedt Bonamy, Anna Karin ; Reims, Annika ; Ahlsson, Fredrik LU ; Elfving, Maria LU ; Domellöf, Magnus and Hansen Pupp, Ingrid LU
(2020)
In Acta Paediatrica, International Journal of Paediatrics
109(1).
p.31-44
- Abstract
Aim: Postnatal hypoglycaemia in newborn infants remains an important clinical problem where prolonged periods of hypoglycaemia are associated with poor neurodevelopmental outcome. The aim was to develop an evidence-based national guideline with the purpose to optimise prevention, diagnosis and treatment of hypoglycaemia in newborn infants with a gestational age ≥35 + 0 weeks. Methods: A PubMed search-based literature review was used to find actual and applicable evidence for all incorporated recommendations. The GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach was used for grading the evidence of the recommendations. Results: Recommendations for the prevention of neonatal hypoglycaemia were extended... (More)
Aim: Postnatal hypoglycaemia in newborn infants remains an important clinical problem where prolonged periods of hypoglycaemia are associated with poor neurodevelopmental outcome. The aim was to develop an evidence-based national guideline with the purpose to optimise prevention, diagnosis and treatment of hypoglycaemia in newborn infants with a gestational age ≥35 + 0 weeks. Methods: A PubMed search-based literature review was used to find actual and applicable evidence for all incorporated recommendations. The GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach was used for grading the evidence of the recommendations. Results: Recommendations for the prevention of neonatal hypoglycaemia were extended and updated, focusing on promotion of breastfeeding as one prevention strategy. Oral dextrose gel as a novel supplemental therapy was incorporated in the treatment protocol. A new threshold-based screening and treatment protocol presented as a flow chart was developed. Conclusion: An updated and evidence-based national guideline for screening and treatment of neonatal hypoglycaemia will support standardised regimes, which may prevent hypoglycaemia and the risk for hypoglycaemia-related long-term sequelae.
(Less)
- author
- Wackernagel, Dirk
; Gustafsson, Anna
; Edstedt Bonamy, Anna Karin
; Reims, Annika
; Ahlsson, Fredrik
LU
; Elfving, Maria
LU
; Domellöf, Magnus
and Hansen Pupp, Ingrid
LU
- organization
- publishing date
- 2020
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- breastfeeding, dextrose gel, guideline, hypoglycaemia, newborn infant
- in
- Acta Paediatrica, International Journal of Paediatrics
- volume
- 109
- issue
- 1
- pages
- 31 - 44
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85071339419
- pmid:31350926
- ISSN
- 0803-5253
- DOI
- 10.1111/apa.14955
- language
- English
- LU publication?
- yes
- id
- 1f96e326-f092-4d02-bbdb-70d82f240fb3
- date added to LUP
- 2019-09-03 08:21:06
- date last changed
- 2024-04-16 18:44:08
@article{1f96e326-f092-4d02-bbdb-70d82f240fb3,
abstract = {{<p>Aim: Postnatal hypoglycaemia in newborn infants remains an important clinical problem where prolonged periods of hypoglycaemia are associated with poor neurodevelopmental outcome. The aim was to develop an evidence-based national guideline with the purpose to optimise prevention, diagnosis and treatment of hypoglycaemia in newborn infants with a gestational age ≥35 + 0 weeks. Methods: A PubMed search-based literature review was used to find actual and applicable evidence for all incorporated recommendations. The GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach was used for grading the evidence of the recommendations. Results: Recommendations for the prevention of neonatal hypoglycaemia were extended and updated, focusing on promotion of breastfeeding as one prevention strategy. Oral dextrose gel as a novel supplemental therapy was incorporated in the treatment protocol. A new threshold-based screening and treatment protocol presented as a flow chart was developed. Conclusion: An updated and evidence-based national guideline for screening and treatment of neonatal hypoglycaemia will support standardised regimes, which may prevent hypoglycaemia and the risk for hypoglycaemia-related long-term sequelae.</p>}},
author = {{Wackernagel, Dirk and Gustafsson, Anna and Edstedt Bonamy, Anna Karin and Reims, Annika and Ahlsson, Fredrik and Elfving, Maria and Domellöf, Magnus and Hansen Pupp, Ingrid}},
issn = {{0803-5253}},
keywords = {{breastfeeding; dextrose gel; guideline; hypoglycaemia; newborn infant}},
language = {{eng}},
number = {{1}},
pages = {{31--44}},
publisher = {{Wiley-Blackwell}},
series = {{Acta Paediatrica, International Journal of Paediatrics}},
title = {{Swedish national guideline for prevention and treatment of neonatal hypoglycaemia in newborn infants with gestational age ≥35 weeks}},
url = {{http://dx.doi.org/10.1111/apa.14955}},
doi = {{10.1111/apa.14955}},
volume = {{109}},
year = {{2020}},
}