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Biomaterials for in vitro models in lung research

Ibáñez-Fonseca, Arturo LU orcid and Elowsson, Linda LU (2022) p.91-107
Abstract

In this chapter we introduce biomaterials science to a nonexpert reader in order to provide new perspectives for the development of in vitro three-dimensional models that are relevant in lung research. Specifically, we provide a comprehensive description of key concepts in the fields of biomaterials science and lung research to explain how merging them can give rise to new models of lung biology and disease that prevent overuse of animal models while making it possible to do tests in human lung cells and tissue. Along with the different examples of lung models reviewed here, we answer questions that can help a researcher in the lung field to understand the studies: what biomaterial, why this biomaterial, and how it has been used.... (More)

In this chapter we introduce biomaterials science to a nonexpert reader in order to provide new perspectives for the development of in vitro three-dimensional models that are relevant in lung research. Specifically, we provide a comprehensive description of key concepts in the fields of biomaterials science and lung research to explain how merging them can give rise to new models of lung biology and disease that prevent overuse of animal models while making it possible to do tests in human lung cells and tissue. Along with the different examples of lung models reviewed here, we answer questions that can help a researcher in the lung field to understand the studies: what biomaterial, why this biomaterial, and how it has been used. Moreover, we discuss important findings and breakthroughs that have been made in the lung field with the use of biomaterials, and we comment on the advantages and disadvantages of these approaches.

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Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
3D microenvironment, 3D model, bioactive, biodegradable, Biomaterials, hydrogel, lung, scaffold, stiffness, tissue engineering
host publication
3D Lung Models for Regenerating Lung Tissue
pages
17 pages
publisher
ScienceDirect, Elsevier
external identifiers
  • scopus:85142849217
ISBN
9780323908726
9780323908719
DOI
10.1016/B978-0-323-90871-9.00007-3
language
English
LU publication?
yes
id
2036dddb-9e8b-40b1-9ded-9d33d31a79de
date added to LUP
2022-12-27 12:00:03
date last changed
2024-05-30 23:18:31
@inbook{2036dddb-9e8b-40b1-9ded-9d33d31a79de,
  abstract     = {{<p>In this chapter we introduce biomaterials science to a nonexpert reader in order to provide new perspectives for the development of in vitro three-dimensional models that are relevant in lung research. Specifically, we provide a comprehensive description of key concepts in the fields of biomaterials science and lung research to explain how merging them can give rise to new models of lung biology and disease that prevent overuse of animal models while making it possible to do tests in human lung cells and tissue. Along with the different examples of lung models reviewed here, we answer questions that can help a researcher in the lung field to understand the studies: what biomaterial, why this biomaterial, and how it has been used. Moreover, we discuss important findings and breakthroughs that have been made in the lung field with the use of biomaterials, and we comment on the advantages and disadvantages of these approaches.</p>}},
  author       = {{Ibáñez-Fonseca, Arturo and Elowsson, Linda}},
  booktitle    = {{3D Lung Models for Regenerating Lung Tissue}},
  isbn         = {{9780323908726}},
  keywords     = {{3D microenvironment; 3D model; bioactive; biodegradable; Biomaterials; hydrogel; lung; scaffold; stiffness; tissue engineering}},
  language     = {{eng}},
  pages        = {{91--107}},
  publisher    = {{ScienceDirect, Elsevier}},
  title        = {{Biomaterials for in vitro models in lung research}},
  url          = {{http://dx.doi.org/10.1016/B978-0-323-90871-9.00007-3}},
  doi          = {{10.1016/B978-0-323-90871-9.00007-3}},
  year         = {{2022}},
}