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Interfacial Molecular Imprinting in Nanoparticle-Stabilized Emulsions.

Shen, Xiantao LU and Ye, Lei LU (2011) In Macromolecules 44(14). p.5631-5637
Abstract
A new interfacial nano and molecular imprinting approach is developed to prepare spherical molecularly imprinted polymers with well-controlled hierarchical structures. This method is based on Pickering emulsion polymerization using template-modified colloidal particles. The interfacial imprinting is carried out in particle-stabilized oil-in-water emulsions, where the molecular template is presented on the surface of silica nanoparticles during the polymerization of the monomer phase. After polymerization, the template-modified silica nanoparticles are removed from the new spherical particles to leave tiny indentations decorated with molecularly imprinted sites. The imprinted microspheres prepared using the new interfacial nano and... (More)
A new interfacial nano and molecular imprinting approach is developed to prepare spherical molecularly imprinted polymers with well-controlled hierarchical structures. This method is based on Pickering emulsion polymerization using template-modified colloidal particles. The interfacial imprinting is carried out in particle-stabilized oil-in-water emulsions, where the molecular template is presented on the surface of silica nanoparticles during the polymerization of the monomer phase. After polymerization, the template-modified silica nanoparticles are removed from the new spherical particles to leave tiny indentations decorated with molecularly imprinted sites. The imprinted microspheres prepared using the new interfacial nano and molecular imprinting have very interesting features: a well-controlled hierarchical structure composed of large pores decorated with easily accessible molecular binding sites, group selectivity toward a series of chemicals having a common structural moiety (epitopes), and a hydrophilic surface that enables the MIPs to be used under aqueous conditions. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Macromolecules
volume
44
issue
14
pages
5631 - 5637
publisher
The American Chemical Society
external identifiers
  • wos:000292850100013
  • scopus:79960534568
ISSN
0024-9297
DOI
10.1021/ma200837n
language
English
LU publication?
yes
id
0db4cbf4-84fd-4a5a-b272-ea248264928b (old id 2058377)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/21779131?dopt=Abstract
date added to LUP
2011-07-27 10:09:13
date last changed
2017-08-27 03:23:54
@article{0db4cbf4-84fd-4a5a-b272-ea248264928b,
  abstract     = {A new interfacial nano and molecular imprinting approach is developed to prepare spherical molecularly imprinted polymers with well-controlled hierarchical structures. This method is based on Pickering emulsion polymerization using template-modified colloidal particles. The interfacial imprinting is carried out in particle-stabilized oil-in-water emulsions, where the molecular template is presented on the surface of silica nanoparticles during the polymerization of the monomer phase. After polymerization, the template-modified silica nanoparticles are removed from the new spherical particles to leave tiny indentations decorated with molecularly imprinted sites. The imprinted microspheres prepared using the new interfacial nano and molecular imprinting have very interesting features: a well-controlled hierarchical structure composed of large pores decorated with easily accessible molecular binding sites, group selectivity toward a series of chemicals having a common structural moiety (epitopes), and a hydrophilic surface that enables the MIPs to be used under aqueous conditions.},
  author       = {Shen, Xiantao and Ye, Lei},
  issn         = {0024-9297},
  language     = {eng},
  number       = {14},
  pages        = {5631--5637},
  publisher    = {The American Chemical Society},
  series       = {Macromolecules},
  title        = {Interfacial Molecular Imprinting in Nanoparticle-Stabilized Emulsions.},
  url          = {http://dx.doi.org/10.1021/ma200837n},
  volume       = {44},
  year         = {2011},
}