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Antidepressant therapy in severe depression may have different effects on ego-dystonic and ego-syntonic suicidal ideation.

Brådvik, Louise LU and Berglund, Mats LU (2011) In Depression Research and Treatment 2011(Article ID 896395).
Abstract
The objective of the present study was to investigate whether ego-dystonic and ego-syntonic suicidal ideation occurred at different frequencies during antidepressant therapy. A blind evaluation has been performed on records of 100 suicides with a primary severe depression and 100 matched controls, admitted to the Department of Psychiatry, Lund, Sweden. Ego-dystonic suicidal ideation was more commonly reported during adequate treatment as compared to ego-syntonic ideation (P = .004). Men who committed suicide during adequate antidepressant therapy more often reported ego-dystonic suicidal ideation earlier in their lives compared with those who were not treated (P = .0377). This may indicate that treatment failure for ego-dystonic ideation... (More)
The objective of the present study was to investigate whether ego-dystonic and ego-syntonic suicidal ideation occurred at different frequencies during antidepressant therapy. A blind evaluation has been performed on records of 100 suicides with a primary severe depression and 100 matched controls, admitted to the Department of Psychiatry, Lund, Sweden. Ego-dystonic suicidal ideation was more commonly reported during adequate treatment as compared to ego-syntonic ideation (P = .004). Men who committed suicide during adequate antidepressant therapy more often reported ego-dystonic suicidal ideation earlier in their lives compared with those who were not treated (P = .0377). This may indicate that treatment failure for ego-dystonic ideation was a precursor of their suicides. Consequently, ego-dystonic ideation seems to show a poorer response to antidepressant therapy as compared to ego-syntonic ideation, which may be more directly related to depression. Ego-dystonic ideation is proposed to be related to depressive psychosis. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Depression Research and Treatment
volume
2011
issue
Article ID 896395
publisher
Hindawi Publishing Corporation
external identifiers
  • pmid:21738871
  • scopus:84873860022
ISSN
2090-133X
DOI
10.1155/2011/896395
language
English
LU publication?
yes
id
f539a605-7a01-4b6f-9398-7939e6e90164 (old id 2058817)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/21738871?dopt=Abstract
date added to LUP
2011-08-01 18:54:29
date last changed
2017-01-01 03:17:08
@article{f539a605-7a01-4b6f-9398-7939e6e90164,
  abstract     = {The objective of the present study was to investigate whether ego-dystonic and ego-syntonic suicidal ideation occurred at different frequencies during antidepressant therapy. A blind evaluation has been performed on records of 100 suicides with a primary severe depression and 100 matched controls, admitted to the Department of Psychiatry, Lund, Sweden. Ego-dystonic suicidal ideation was more commonly reported during adequate treatment as compared to ego-syntonic ideation (P = .004). Men who committed suicide during adequate antidepressant therapy more often reported ego-dystonic suicidal ideation earlier in their lives compared with those who were not treated (P = .0377). This may indicate that treatment failure for ego-dystonic ideation was a precursor of their suicides. Consequently, ego-dystonic ideation seems to show a poorer response to antidepressant therapy as compared to ego-syntonic ideation, which may be more directly related to depression. Ego-dystonic ideation is proposed to be related to depressive psychosis.},
  articleno    = {896395},
  author       = {Brådvik, Louise and Berglund, Mats},
  issn         = {2090-133X},
  language     = {eng},
  number       = {Article ID 896395},
  publisher    = {Hindawi Publishing Corporation},
  series       = {Depression Research and Treatment},
  title        = {Antidepressant therapy in severe depression may have different effects on ego-dystonic and ego-syntonic suicidal ideation.},
  url          = {http://dx.doi.org/10.1155/2011/896395},
  volume       = {2011},
  year         = {2011},
}