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Is craniofacial dysmorpholgy correlated with structural brain anomalies in schizophrenia?

Kelly, BD; McNeil, Thomas LU ; Lane, A; Henriksson, Karin LU ; Kinsella, A and Agartz, I (2005) In Schizophrenia Research 80(2-3). p.349-355
Abstract
This study aimed to examine the relationship between craniofacial dysmorphology and anomalies of brain morphology in schizophrenia. Assessments of craniofacial dysmorphology and magnetic resonance imaging of brain were performed independently of each other and blind to each other in 24 males with schizophrenia and 16 male controls. Ventricular cerebrospinal fluid volume was negatively correlated with total dysmorphology score in males with schizophrenia (i.e., the larger the ventricular cerebrospinal fluid volume, the lower the total dysmorphology score) but not in male controls. These findings suggest that craniofacial dysmorphology and anomalies of brain morphology may be associated with independent processes in the etiology of... (More)
This study aimed to examine the relationship between craniofacial dysmorphology and anomalies of brain morphology in schizophrenia. Assessments of craniofacial dysmorphology and magnetic resonance imaging of brain were performed independently of each other and blind to each other in 24 males with schizophrenia and 16 male controls. Ventricular cerebrospinal fluid volume was negatively correlated with total dysmorphology score in males with schizophrenia (i.e., the larger the ventricular cerebrospinal fluid volume, the lower the total dysmorphology score) but not in male controls. These findings suggest that craniofacial dysmorphology and anomalies of brain morphology may be associated with independent processes in the etiology of schizophrenia. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
human, anthropometry, schizophrenia, magnetic resonance imaging, development, causality
in
Schizophrenia Research
volume
80
issue
2-3
pages
349 - 355
publisher
Elsevier
external identifiers
  • pmid:16154323
  • wos:000234757600022
  • scopus:28244460026
ISSN
0920-9964
DOI
10.1016/j.schres.2005.07.036
language
English
LU publication?
yes
id
3d4f8614-af49-4bdf-9c24-7e0aa724bc6c (old id 209730)
date added to LUP
2007-08-15 11:35:25
date last changed
2017-01-01 04:24:50
@article{3d4f8614-af49-4bdf-9c24-7e0aa724bc6c,
  abstract     = {This study aimed to examine the relationship between craniofacial dysmorphology and anomalies of brain morphology in schizophrenia. Assessments of craniofacial dysmorphology and magnetic resonance imaging of brain were performed independently of each other and blind to each other in 24 males with schizophrenia and 16 male controls. Ventricular cerebrospinal fluid volume was negatively correlated with total dysmorphology score in males with schizophrenia (i.e., the larger the ventricular cerebrospinal fluid volume, the lower the total dysmorphology score) but not in male controls. These findings suggest that craniofacial dysmorphology and anomalies of brain morphology may be associated with independent processes in the etiology of schizophrenia.},
  author       = {Kelly, BD and McNeil, Thomas and Lane, A and Henriksson, Karin and Kinsella, A and Agartz, I},
  issn         = {0920-9964},
  keyword      = {human,anthropometry,schizophrenia,magnetic resonance imaging,development,causality},
  language     = {eng},
  number       = {2-3},
  pages        = {349--355},
  publisher    = {Elsevier},
  series       = {Schizophrenia Research},
  title        = {Is craniofacial dysmorpholgy correlated with structural brain anomalies in schizophrenia?},
  url          = {http://dx.doi.org/10.1016/j.schres.2005.07.036},
  volume       = {80},
  year         = {2005},
}