Mushroom immunomodulators: unique molecules with unlimited applications
(2013) In Trends in Biotechnology 31(12). p.668-677- Abstract
- For centuries, mushrooms have been used as food and medicine in different cultures. More recently, many bioactive compounds have been isolated from different types of mushrooms. Among these, immunomodulators have gained much interest based on the increasing growth of the immunotherapy sector. Mushroom immunomodulators are classified under four categories based on their chemical nature as: lectins, terpenoids, proteins, and polysaccharides. These compounds are produced naturally in mushrooms cultivated in greenhouses. For effective industrial production, cultivation is carried out in submerged culture to increase the bioactive compound yield, decrease the production time, and reduce the cost of downstream processing. This review provides a... (More)
- For centuries, mushrooms have been used as food and medicine in different cultures. More recently, many bioactive compounds have been isolated from different types of mushrooms. Among these, immunomodulators have gained much interest based on the increasing growth of the immunotherapy sector. Mushroom immunomodulators are classified under four categories based on their chemical nature as: lectins, terpenoids, proteins, and polysaccharides. These compounds are produced naturally in mushrooms cultivated in greenhouses. For effective industrial production, cultivation is carried out in submerged culture to increase the bioactive compound yield, decrease the production time, and reduce the cost of downstream processing. This review provides a comprehensive overview on mushroom immunomodulators in terms of chemistry, industrial production, and applications in medical and nonmedical sectors. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4269127
- author
- El Enshasy, Hesham A. and Hatti-Kaul, Rajni LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- mushroom immunomodulators, lectins, fungal immunomodulatory proteins, polysaccharides, terpenes and terpenoids, medical application, animal, feed and aquaculture, industrial production
- in
- Trends in Biotechnology
- volume
- 31
- issue
- 12
- pages
- 668 - 677
- publisher
- Elsevier
- external identifiers
-
- wos:000328668100002
- scopus:84888136931
- pmid:24125745
- ISSN
- 0167-7799
- DOI
- 10.1016/j.tibtech.2013.09.003
- language
- English
- LU publication?
- yes
- id
- 20b4c0d1-a578-4337-9205-919155906f12 (old id 4269127)
- date added to LUP
- 2016-04-01 10:15:44
- date last changed
- 2022-04-20 00:20:05
@article{20b4c0d1-a578-4337-9205-919155906f12,
abstract = {{For centuries, mushrooms have been used as food and medicine in different cultures. More recently, many bioactive compounds have been isolated from different types of mushrooms. Among these, immunomodulators have gained much interest based on the increasing growth of the immunotherapy sector. Mushroom immunomodulators are classified under four categories based on their chemical nature as: lectins, terpenoids, proteins, and polysaccharides. These compounds are produced naturally in mushrooms cultivated in greenhouses. For effective industrial production, cultivation is carried out in submerged culture to increase the bioactive compound yield, decrease the production time, and reduce the cost of downstream processing. This review provides a comprehensive overview on mushroom immunomodulators in terms of chemistry, industrial production, and applications in medical and nonmedical sectors.}},
author = {{El Enshasy, Hesham A. and Hatti-Kaul, Rajni}},
issn = {{0167-7799}},
keywords = {{mushroom immunomodulators; lectins; fungal immunomodulatory proteins; polysaccharides; terpenes and terpenoids; medical application; animal; feed and aquaculture; industrial production}},
language = {{eng}},
number = {{12}},
pages = {{668--677}},
publisher = {{Elsevier}},
series = {{Trends in Biotechnology}},
title = {{Mushroom immunomodulators: unique molecules with unlimited applications}},
url = {{http://dx.doi.org/10.1016/j.tibtech.2013.09.003}},
doi = {{10.1016/j.tibtech.2013.09.003}},
volume = {{31}},
year = {{2013}},
}