The infantile hemangioma referral score : A validated tool for physicians
(2020) In Pediatrics 145(4).- Abstract
OBJECTIVES: Infantile hemangiomas (IHs) are common; some cases require timely referral and treatment to prevent complications. We developed and validated a reliable instrument for timely and adequate referral of patients with IH to experts by nonexpert primary physicians. METHODS: In this multicenter, cross-sectional, observational study, we used a 3-stage process: (1) development of the Infantile Hemangioma Referral Score (IHReS) tool by IH experts who selected a representative set of 42 IH cases comprising images and a short clinical history, (2) definition of the gold standard for the 42 cases by a second independent committee of IH experts, and (3) IHReS validation by nonexpert primary physicians using the 42 gold standard cases.... (More)
OBJECTIVES: Infantile hemangiomas (IHs) are common; some cases require timely referral and treatment to prevent complications. We developed and validated a reliable instrument for timely and adequate referral of patients with IH to experts by nonexpert primary physicians. METHODS: In this multicenter, cross-sectional, observational study, we used a 3-stage process: (1) development of the Infantile Hemangioma Referral Score (IHReS) tool by IH experts who selected a representative set of 42 IH cases comprising images and a short clinical history, (2) definition of the gold standard for the 42 cases by a second independent committee of IH experts, and (3) IHReS validation by nonexpert primary physicians using the 42 gold standard cases. RESULTS: A total of 60 primary physicians from 7 different countries evaluated the 42 gold standard cases (without reference to the IHReS tool); 45 primary physicians evaluated these cases using the IHReS questionnaire, and 44 completed retesting using the instrument. IHReS had a sensitivity of 96.9% (95% confidence interval 96.1%–97.8%) and a specificity of 55.0% (95% confidence interval 51.0%–59.0%). The positive predictive value and negative predictive value were 40.5% and 98.3%, respectively. Validation by experts and primary physicians revealed substantial agreement for interrater reliability and intrarater repeatability. CONCLUSIONS: IHReS, a 2-part algorithm with a total of 12 questions, is an easy-to-use tool for primary physicians for the purpose of facilitating correct and timely referral of patients with IH. IHReS may help practitioners in their decision to refer patients to expert centers.
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- author
- Léauté-Labrèze, Christine ; Torres, Eulalia Baselga ; Weibel, Lisa ; Boon, Laurence M. ; El Hachem, Maya ; van der Vleuten, Catharina ; Roessler, Jochen and Rubin, Agneta Troilius LU
- publishing date
- 2020-04
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Pediatrics
- volume
- 145
- issue
- 4
- article number
- e20191628
- publisher
- American Academy of Pediatrics
- external identifiers
-
- pmid:32161112
- scopus:85082809032
- ISSN
- 0031-4005
- DOI
- 10.1542/peds.2019-1628
- language
- English
- LU publication?
- no
- id
- 210f9c30-307b-4f76-919e-6e8f959eb9ef
- date added to LUP
- 2020-04-17 15:32:53
- date last changed
- 2024-04-17 06:55:12
@article{210f9c30-307b-4f76-919e-6e8f959eb9ef,
abstract = {{<p>OBJECTIVES: Infantile hemangiomas (IHs) are common; some cases require timely referral and treatment to prevent complications. We developed and validated a reliable instrument for timely and adequate referral of patients with IH to experts by nonexpert primary physicians. METHODS: In this multicenter, cross-sectional, observational study, we used a 3-stage process: (1) development of the Infantile Hemangioma Referral Score (IHReS) tool by IH experts who selected a representative set of 42 IH cases comprising images and a short clinical history, (2) definition of the gold standard for the 42 cases by a second independent committee of IH experts, and (3) IHReS validation by nonexpert primary physicians using the 42 gold standard cases. RESULTS: A total of 60 primary physicians from 7 different countries evaluated the 42 gold standard cases (without reference to the IHReS tool); 45 primary physicians evaluated these cases using the IHReS questionnaire, and 44 completed retesting using the instrument. IHReS had a sensitivity of 96.9% (95% confidence interval 96.1%–97.8%) and a specificity of 55.0% (95% confidence interval 51.0%–59.0%). The positive predictive value and negative predictive value were 40.5% and 98.3%, respectively. Validation by experts and primary physicians revealed substantial agreement for interrater reliability and intrarater repeatability. CONCLUSIONS: IHReS, a 2-part algorithm with a total of 12 questions, is an easy-to-use tool for primary physicians for the purpose of facilitating correct and timely referral of patients with IH. IHReS may help practitioners in their decision to refer patients to expert centers.</p>}},
author = {{Léauté-Labrèze, Christine and Torres, Eulalia Baselga and Weibel, Lisa and Boon, Laurence M. and El Hachem, Maya and van der Vleuten, Catharina and Roessler, Jochen and Rubin, Agneta Troilius}},
issn = {{0031-4005}},
language = {{eng}},
number = {{4}},
publisher = {{American Academy of Pediatrics}},
series = {{Pediatrics}},
title = {{The infantile hemangioma referral score : A validated tool for physicians}},
url = {{http://dx.doi.org/10.1542/peds.2019-1628}},
doi = {{10.1542/peds.2019-1628}},
volume = {{145}},
year = {{2020}},
}