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Renal concentrating capacity in female outpatients with symptomatic urinary tract infection

Stattin Norinder, Birgit; Sandberg, Tove LU and Norrby, R (2005) In Scandinavian Journal of Urology and Nephrology1967-01-01+01:002013-01-01+01:00 39(6). p.483-487
Abstract
Objective. Renal concentrating capacity (RCC) has been used as a tool in the diagnosis of the site of urinary tract infection (UTI). In this study, RCC was measured in women with symptoms of UTI in relation to the clinical picture and the bacterial species isolated. Material and methods. In 633 outpatients aged >= 18 years with symptoms of UTI, a renal concentration test with desmopressin was performed at baseline. The test was repeated after antibiotic treatment in a subset of patients with osmolality values below the reference levels at entry. The bacterial species were identified and patients were classified as having either pyelonephritis or cystitis. Results. RCC was reduced in patients infected with Escherichia coli or... (More)
Objective. Renal concentrating capacity (RCC) has been used as a tool in the diagnosis of the site of urinary tract infection (UTI). In this study, RCC was measured in women with symptoms of UTI in relation to the clinical picture and the bacterial species isolated. Material and methods. In 633 outpatients aged >= 18 years with symptoms of UTI, a renal concentration test with desmopressin was performed at baseline. The test was repeated after antibiotic treatment in a subset of patients with osmolality values below the reference levels at entry. The bacterial species were identified and patients were classified as having either pyelonephritis or cystitis. Results. RCC was reduced in patients infected with Escherichia coli or Staphylococcus saprophyticus compared to those who had negative urine cultures and increased after antibiotic treatment. Patients with symptoms of both pyelonephritis and cystitis had reduced RCC: 44/68 (65%) and 205/457 (45%), respectively. Conclusions. These findings demonstrate a considerable overlap in RCC between patients with pyelonephritis and cystitis, making the osmolality test unreliable for the purpose of diagnosis of the site of UTI. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
renal concentrating capacity, pyelonephritis, cystitis, osmolality, urinary tract infection
in
Scandinavian Journal of Urology and Nephrology1967-01-01+01:002013-01-01+01:00
volume
39
issue
6
pages
483 - 487
publisher
Taylor & Francis
external identifiers
  • wos:000233475700008
  • scopus:28444488577
ISSN
0036-5599
DOI
10.1080/00365590500342950
language
English
LU publication?
yes
id
d6c17620-9399-4da7-8f83-d9a2eab2dd76 (old id 212015)
date added to LUP
2007-08-23 17:29:42
date last changed
2017-01-01 07:04:03
@article{d6c17620-9399-4da7-8f83-d9a2eab2dd76,
  abstract     = {Objective. Renal concentrating capacity (RCC) has been used as a tool in the diagnosis of the site of urinary tract infection (UTI). In this study, RCC was measured in women with symptoms of UTI in relation to the clinical picture and the bacterial species isolated. Material and methods. In 633 outpatients aged >= 18 years with symptoms of UTI, a renal concentration test with desmopressin was performed at baseline. The test was repeated after antibiotic treatment in a subset of patients with osmolality values below the reference levels at entry. The bacterial species were identified and patients were classified as having either pyelonephritis or cystitis. Results. RCC was reduced in patients infected with Escherichia coli or Staphylococcus saprophyticus compared to those who had negative urine cultures and increased after antibiotic treatment. Patients with symptoms of both pyelonephritis and cystitis had reduced RCC: 44/68 (65%) and 205/457 (45%), respectively. Conclusions. These findings demonstrate a considerable overlap in RCC between patients with pyelonephritis and cystitis, making the osmolality test unreliable for the purpose of diagnosis of the site of UTI.},
  author       = {Stattin Norinder, Birgit and Sandberg, Tove and Norrby, R},
  issn         = {0036-5599},
  keyword      = {renal concentrating capacity,pyelonephritis,cystitis,osmolality,urinary tract infection},
  language     = {eng},
  number       = {6},
  pages        = {483--487},
  publisher    = {Taylor & Francis},
  series       = {Scandinavian Journal of Urology and Nephrology1967-01-01+01:002013-01-01+01:00},
  title        = {Renal concentrating capacity in female outpatients with symptomatic urinary tract infection},
  url          = {http://dx.doi.org/10.1080/00365590500342950},
  volume       = {39},
  year         = {2005},
}