Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Comparison between transcranial Doppler and coulter counter for detection of lipid micro embolization from mediastinal shed blood reinfusion during cardiac surgery.

Eyjolfsson, Atli LU ; Alrashidi, Faleh LU ; Dencker, Magnus LU ; Scicluna, Sara LU ; Brondén, Björn LU ; Koul, Bansi LU and Bjursten, Henrik LU (2011) In Perfusion 26(5). p.519-523
Abstract
INTRODUCTION: Lipid micro embolization (LME) from re-transfused shed blood has been postulated to be a potential reason for short- and long-term cognitive dysfunction after cardiac surgery. The purpose of this investigation was to evaluate if transcranial Doppler (TCD) has the capacity to detect LME. METHODS: Thirteen patients undergoing cardiopulmonary bypass surgery were investigated. Each patient's cerebral circulation was monitored with transcranial Doppler during the first two minutes after re-transfusion of shed blood and blood was simultaneously sampled and characterised by a Coulter counter. RESULTS: Strong correlation was found between embolic loads, as measured by transcranial Doppler and Coulter counter (r=0.79, P<0.005).... (More)
INTRODUCTION: Lipid micro embolization (LME) from re-transfused shed blood has been postulated to be a potential reason for short- and long-term cognitive dysfunction after cardiac surgery. The purpose of this investigation was to evaluate if transcranial Doppler (TCD) has the capacity to detect LME. METHODS: Thirteen patients undergoing cardiopulmonary bypass surgery were investigated. Each patient's cerebral circulation was monitored with transcranial Doppler during the first two minutes after re-transfusion of shed blood and blood was simultaneously sampled and characterised by a Coulter counter. RESULTS: Strong correlation was found between embolic loads, as measured by transcranial Doppler and Coulter counter (r=0.79, P<0.005). CONCLUSIONS: This pilot study shows that non-invasive monitoring by transcranial Doppler could be a potential tool to monitor LME during cardiopulmonary bypass surgery. (Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Perfusion
volume
26
issue
5
pages
519 - 523
publisher
SAGE Publications
external identifiers
  • wos:000297503600011
  • pmid:21844112
  • scopus:80155172562
  • pmid:21844112
ISSN
1477-111X
DOI
10.1177/0267659111419033
language
English
LU publication?
yes
id
dfd9e9ff-b180-44b6-bae1-06031719bf76 (old id 2151043)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/21844112?dopt=Abstract
date added to LUP
2016-04-01 10:40:47
date last changed
2021-02-17 07:32:09
@article{dfd9e9ff-b180-44b6-bae1-06031719bf76,
  abstract     = {INTRODUCTION: Lipid micro embolization (LME) from re-transfused shed blood has been postulated to be a potential reason for short- and long-term cognitive dysfunction after cardiac surgery. The purpose of this investigation was to evaluate if transcranial Doppler (TCD) has the capacity to detect LME. METHODS: Thirteen patients undergoing cardiopulmonary bypass surgery were investigated. Each patient's cerebral circulation was monitored with transcranial Doppler during the first two minutes after re-transfusion of shed blood and blood was simultaneously sampled and characterised by a Coulter counter. RESULTS: Strong correlation was found between embolic loads, as measured by transcranial Doppler and Coulter counter (r=0.79, P&lt;0.005). CONCLUSIONS: This pilot study shows that non-invasive monitoring by transcranial Doppler could be a potential tool to monitor LME during cardiopulmonary bypass surgery.},
  author       = {Eyjolfsson, Atli and Alrashidi, Faleh and Dencker, Magnus and Scicluna, Sara and Brondén, Björn and Koul, Bansi and Bjursten, Henrik},
  issn         = {1477-111X},
  language     = {eng},
  number       = {5},
  pages        = {519--523},
  publisher    = {SAGE Publications},
  series       = {Perfusion},
  title        = {Comparison between transcranial Doppler and coulter counter for detection of lipid micro embolization from mediastinal shed blood reinfusion during cardiac surgery.},
  url          = {http://dx.doi.org/10.1177/0267659111419033},
  doi          = {10.1177/0267659111419033},
  volume       = {26},
  year         = {2011},
}