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Comparison between transcranial Doppler and coulter counter for detection of lipid micro embolization from mediastinal shed blood reinfusion during cardiac surgery.

Eyjolfsson, Atli LU ; Alrashidi, Faleh LU ; Dencker, Magnus LU ; Scicluna, Sara LU ; Brondén, Björn LU ; Koul, Bansi LU and Bjursten, Henrik LU (2011) In Perfusion 26(5). p.519-523
Abstract
INTRODUCTION: Lipid micro embolization (LME) from re-transfused shed blood has been postulated to be a potential reason for short- and long-term cognitive dysfunction after cardiac surgery. The purpose of this investigation was to evaluate if transcranial Doppler (TCD) has the capacity to detect LME. METHODS: Thirteen patients undergoing cardiopulmonary bypass surgery were investigated. Each patient's cerebral circulation was monitored with transcranial Doppler during the first two minutes after re-transfusion of shed blood and blood was simultaneously sampled and characterised by a Coulter counter. RESULTS: Strong correlation was found between embolic loads, as measured by transcranial Doppler and Coulter counter (r=0.79, P<0.005).... (More)
INTRODUCTION: Lipid micro embolization (LME) from re-transfused shed blood has been postulated to be a potential reason for short- and long-term cognitive dysfunction after cardiac surgery. The purpose of this investigation was to evaluate if transcranial Doppler (TCD) has the capacity to detect LME. METHODS: Thirteen patients undergoing cardiopulmonary bypass surgery were investigated. Each patient's cerebral circulation was monitored with transcranial Doppler during the first two minutes after re-transfusion of shed blood and blood was simultaneously sampled and characterised by a Coulter counter. RESULTS: Strong correlation was found between embolic loads, as measured by transcranial Doppler and Coulter counter (r=0.79, P<0.005). CONCLUSIONS: This pilot study shows that non-invasive monitoring by transcranial Doppler could be a potential tool to monitor LME during cardiopulmonary bypass surgery. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Perfusion
volume
26
issue
5
pages
519 - 523
publisher
SAGE Publications Inc.
external identifiers
  • wos:000297503600011
  • pmid:21844112
  • scopus:80155172562
ISSN
1477-111X
DOI
10.1177/0267659111419033
language
English
LU publication?
yes
id
dfd9e9ff-b180-44b6-bae1-06031719bf76 (old id 2151043)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/21844112?dopt=Abstract
date added to LUP
2011-09-04 14:23:30
date last changed
2017-01-01 03:48:18
@article{dfd9e9ff-b180-44b6-bae1-06031719bf76,
  abstract     = {INTRODUCTION: Lipid micro embolization (LME) from re-transfused shed blood has been postulated to be a potential reason for short- and long-term cognitive dysfunction after cardiac surgery. The purpose of this investigation was to evaluate if transcranial Doppler (TCD) has the capacity to detect LME. METHODS: Thirteen patients undergoing cardiopulmonary bypass surgery were investigated. Each patient's cerebral circulation was monitored with transcranial Doppler during the first two minutes after re-transfusion of shed blood and blood was simultaneously sampled and characterised by a Coulter counter. RESULTS: Strong correlation was found between embolic loads, as measured by transcranial Doppler and Coulter counter (r=0.79, P&lt;0.005). CONCLUSIONS: This pilot study shows that non-invasive monitoring by transcranial Doppler could be a potential tool to monitor LME during cardiopulmonary bypass surgery.},
  author       = {Eyjolfsson, Atli and Alrashidi, Faleh and Dencker, Magnus and Scicluna, Sara and Brondén, Björn and Koul, Bansi and Bjursten, Henrik},
  issn         = {1477-111X},
  language     = {eng},
  number       = {5},
  pages        = {519--523},
  publisher    = {SAGE Publications Inc.},
  series       = {Perfusion},
  title        = {Comparison between transcranial Doppler and coulter counter for detection of lipid micro embolization from mediastinal shed blood reinfusion during cardiac surgery.},
  url          = {http://dx.doi.org/10.1177/0267659111419033},
  volume       = {26},
  year         = {2011},
}