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Elemental Analysis on Freeze-Dried Sections of Human Skin: Studies by Electron Microprobe and Particle Induced X-Ray Emission Analysis

Forslind, Bo; Roomans, G M; Carlsson, Lars-Eric; Malmqvist, Klas LU and Akselsson, Roland LU (1984) In Scanning Electron Microscopy p.755-759
Abstract
The possibility of using the proton microprobe (PMP) in the elemental analysis of dermatological material, under conditions where the spatial resolution can be restricted to a few micrometers, was demonstrated. Comparison with the electron microprobe (EMP) technique using duplicate sections from the same human skin biopsies revealed that the PMP and EMP techniques are complementary and yield closely corresponding elemental distributions for elements of dermatological interest. The concentrations of phosphorus and potassium were low in the dermis, high in the stratum basale and stratum spinosum, and decreased markedly in the stratum granulosum to a low level in the stratum corneum. The sulfur concentration was highest in the stratum corneum.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
skin, particle induced x-ray emission analysis (PIXE), electron probe X-ray microanalysis, cryotechniques, electrolytes, quantitation, mass determination, human, dermatology
in
Scanning Electron Microscopy
pages
755 - 759
publisher
SEM Inc., AMF O'Hare (Chicago), IL, USA
external identifiers
  • scopus:0021197110
ISSN
0586-5581
language
English
LU publication?
yes
id
38a7263f-e7b9-4fef-a456-ddf259a87892 (old id 2154437)
date added to LUP
2011-09-06 15:10:23
date last changed
2017-08-20 04:49:33
@article{38a7263f-e7b9-4fef-a456-ddf259a87892,
  abstract     = {The possibility of using the proton microprobe (PMP) in the elemental analysis of dermatological material, under conditions where the spatial resolution can be restricted to a few micrometers, was demonstrated. Comparison with the electron microprobe (EMP) technique using duplicate sections from the same human skin biopsies revealed that the PMP and EMP techniques are complementary and yield closely corresponding elemental distributions for elements of dermatological interest. The concentrations of phosphorus and potassium were low in the dermis, high in the stratum basale and stratum spinosum, and decreased markedly in the stratum granulosum to a low level in the stratum corneum. The sulfur concentration was highest in the stratum corneum.},
  author       = {Forslind, Bo and Roomans, G M and Carlsson, Lars-Eric and Malmqvist, Klas and Akselsson, Roland},
  issn         = {0586-5581},
  keyword      = {skin,particle induced x-ray emission analysis (PIXE),electron probe X-ray microanalysis,cryotechniques,electrolytes,quantitation,mass determination,human,dermatology},
  language     = {eng},
  pages        = {755--759},
  publisher    = {SEM Inc., AMF O'Hare (Chicago), IL, USA},
  series       = {Scanning Electron Microscopy},
  title        = {Elemental Analysis on Freeze-Dried Sections of Human Skin: Studies by Electron Microprobe and Particle Induced X-Ray Emission Analysis},
  year         = {1984},
}