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Determination of sorption of seventy-five pharmaceuticals in sewage sludge

Hörsing, Maritha LU ; Ledin, Anna; Grabic, Roman; Fick, Jerker; Tysklind, Mats; la Cour Jansen, Jes LU and Andersen, Henrik R. (2011) In Water Research 45(15). p.4470-4482
Abstract
Sorption of 75 active pharmaceutical ingredients (APIs) to three different types of sludge (primary sludge, secondary sludge with short and long sludge age respectively) were investigated. To obtain the sorption isotherms batch studies with the APIs mixture were performed in four nominal concentrations to water containing 1 g of sludge. The range of APIs concentrations was between ng L-1 to mu g L-1 which are found in the wastewater effluents. Isotherms were obtained for approximately 45 of the APIs, providing distribution coefficients for linear (K-d), Freundlich (K-f) and Langmuir (K-L) isotherms. K-d, K-f and K-L ranging between 7.1 x 10(4) and 3.8 x 10(7), 1.1 x 10(-2) and 6.1 x 10(4) and 9.2 x 10(-3) and 1.1 L kg(-1), respectively.... (More)
Sorption of 75 active pharmaceutical ingredients (APIs) to three different types of sludge (primary sludge, secondary sludge with short and long sludge age respectively) were investigated. To obtain the sorption isotherms batch studies with the APIs mixture were performed in four nominal concentrations to water containing 1 g of sludge. The range of APIs concentrations was between ng L-1 to mu g L-1 which are found in the wastewater effluents. Isotherms were obtained for approximately 45 of the APIs, providing distribution coefficients for linear (K-d), Freundlich (K-f) and Langmuir (K-L) isotherms. K-d, K-f and K-L ranging between 7.1 x 10(4) and 3.8 x 10(7), 1.1 x 10(-2) and 6.1 x 10(4) and 9.2 x 10(-3) and 1.1 L kg(-1), respectively. The obtained coefficients were applied to estimate the fraction of APIs in the water phase (see Abstract Graphic). For 37 of the 75 APIs, the predicted presence in the liquid phase was estimated to >80%. 24 APIs were estimated to be present in the liquid phase between 20 and 80%, and 14 APIs were found to have <20% presence in the liquid phase, i.e. high affinity towards sludge. Furthermore, the effect of pH at values 6, 7 and 8 was evaluated using one way ANOVA-test. A significant difference in K(d)s due to pH changes were found for 6 of the APIs (variation 10-20%). (C) 2011 Elsevier Ltd. All rights reserved. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Distribution coefficients (K-d), Pharmaceuticals, Sorption isotherms, Sludge, Wastewater treatment plant (WWTP)
in
Water Research
volume
45
issue
15
pages
4470 - 4482
publisher
Elsevier
external identifiers
  • wos:000294101300015
  • scopus:79960598336
ISSN
1879-2448
DOI
10.1016/j.watres.2011.05.033
language
English
LU publication?
yes
id
f5e19742-76b0-46ad-a48d-719f124045b3 (old id 2160922)
date added to LUP
2011-09-21 15:15:58
date last changed
2017-11-12 03:45:34
@article{f5e19742-76b0-46ad-a48d-719f124045b3,
  abstract     = {Sorption of 75 active pharmaceutical ingredients (APIs) to three different types of sludge (primary sludge, secondary sludge with short and long sludge age respectively) were investigated. To obtain the sorption isotherms batch studies with the APIs mixture were performed in four nominal concentrations to water containing 1 g of sludge. The range of APIs concentrations was between ng L-1 to mu g L-1 which are found in the wastewater effluents. Isotherms were obtained for approximately 45 of the APIs, providing distribution coefficients for linear (K-d), Freundlich (K-f) and Langmuir (K-L) isotherms. K-d, K-f and K-L ranging between 7.1 x 10(4) and 3.8 x 10(7), 1.1 x 10(-2) and 6.1 x 10(4) and 9.2 x 10(-3) and 1.1 L kg(-1), respectively. The obtained coefficients were applied to estimate the fraction of APIs in the water phase (see Abstract Graphic). For 37 of the 75 APIs, the predicted presence in the liquid phase was estimated to &gt;80%. 24 APIs were estimated to be present in the liquid phase between 20 and 80%, and 14 APIs were found to have &lt;20% presence in the liquid phase, i.e. high affinity towards sludge. Furthermore, the effect of pH at values 6, 7 and 8 was evaluated using one way ANOVA-test. A significant difference in K(d)s due to pH changes were found for 6 of the APIs (variation 10-20%). (C) 2011 Elsevier Ltd. All rights reserved.},
  author       = {Hörsing, Maritha and Ledin, Anna and Grabic, Roman and Fick, Jerker and Tysklind, Mats and la Cour Jansen, Jes and Andersen, Henrik R.},
  issn         = {1879-2448},
  keyword      = {Distribution coefficients (K-d),Pharmaceuticals,Sorption isotherms,Sludge,Wastewater treatment plant (WWTP)},
  language     = {eng},
  number       = {15},
  pages        = {4470--4482},
  publisher    = {Elsevier},
  series       = {Water Research},
  title        = {Determination of sorption of seventy-five pharmaceuticals in sewage sludge},
  url          = {http://dx.doi.org/10.1016/j.watres.2011.05.033},
  volume       = {45},
  year         = {2011},
}