Advanced

Validation of Self-testing as a Method to Estimate the Prevalence of Nickel Allergy

Josefson, Anna; Svensson, Ake; Farm, Gunilla; Engfeldt, Malin LU and Meding, Birgitta (2011) In Acta Dermato-Venereologica 91(5). p.526-530
Abstract
The aim of this study was to investigate the validity of self-patch testing for nickel allergy, in order to determine a cost-effective method for surveillance of the prevalence of nickel allergy. Population-based study including patch testing is the most reliable method to study the prevalence of allergy, but it is expensive and has logistical problems. A total of 191 dermatology patients referred to patch testing were provided with a self-test package with written instructions. The self-test was applied on the arm by the patient, on the same day that the regular patch test was applied on the back. The patient evaluated the self-test before patch test reading at the clinic. Patch test at the dermatology clinic detected 46/191 (24%)... (More)
The aim of this study was to investigate the validity of self-patch testing for nickel allergy, in order to determine a cost-effective method for surveillance of the prevalence of nickel allergy. Population-based study including patch testing is the most reliable method to study the prevalence of allergy, but it is expensive and has logistical problems. A total of 191 dermatology patients referred to patch testing were provided with a self-test package with written instructions. The self-test was applied on the arm by the patient, on the same day that the regular patch test was applied on the back. The patient evaluated the self-test before patch test reading at the clinic. Patch test at the dermatology clinic detected 46/191 (24%) nickel-positive individuals. The sensitivity of the self-test was 72% (95% confidence interval (Cl) 57-84), the specificity 91% (95% Cl 85-95), and the proportion of agreement 86% (95% CI 81-91). Thus, in the population studied, the validity of self-testing for nickel allergy was adequate. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
contact allergy, epidemiology, patch test, self-test, sensitivity, specificity
in
Acta Dermato-Venereologica
volume
91
issue
5
pages
526 - 530
publisher
Medical Journals Limited
external identifiers
  • wos:000294887800006
  • scopus:80051979155
ISSN
1651-2057
DOI
10.2340/00015555-1125
language
English
LU publication?
yes
id
34547d5a-9cfa-4cee-8af3-a15b87e12d5f (old id 2180278)
date added to LUP
2011-11-01 07:49:49
date last changed
2017-10-22 03:59:28
@article{34547d5a-9cfa-4cee-8af3-a15b87e12d5f,
  abstract     = {The aim of this study was to investigate the validity of self-patch testing for nickel allergy, in order to determine a cost-effective method for surveillance of the prevalence of nickel allergy. Population-based study including patch testing is the most reliable method to study the prevalence of allergy, but it is expensive and has logistical problems. A total of 191 dermatology patients referred to patch testing were provided with a self-test package with written instructions. The self-test was applied on the arm by the patient, on the same day that the regular patch test was applied on the back. The patient evaluated the self-test before patch test reading at the clinic. Patch test at the dermatology clinic detected 46/191 (24%) nickel-positive individuals. The sensitivity of the self-test was 72% (95% confidence interval (Cl) 57-84), the specificity 91% (95% Cl 85-95), and the proportion of agreement 86% (95% CI 81-91). Thus, in the population studied, the validity of self-testing for nickel allergy was adequate.},
  author       = {Josefson, Anna and Svensson, Ake and Farm, Gunilla and Engfeldt, Malin and Meding, Birgitta},
  issn         = {1651-2057},
  keyword      = {contact allergy,epidemiology,patch test,self-test,sensitivity,specificity},
  language     = {eng},
  number       = {5},
  pages        = {526--530},
  publisher    = {Medical Journals Limited},
  series       = {Acta Dermato-Venereologica},
  title        = {Validation of Self-testing as a Method to Estimate the Prevalence of Nickel Allergy},
  url          = {http://dx.doi.org/10.2340/00015555-1125},
  volume       = {91},
  year         = {2011},
}