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The spectrum of adult congenital heart disease in Europe: morbidity and mortality in a 5 year follow-up period - The Euro Heart Survey on adult congenital heart disease

Engelfriet, P; Boersma, E; Oechslin, E; Tijssen, J; Gatzoulis, M A; Thilén, Ulf LU ; Kaemmerer, H; Moons, P; Meijboom, F and Popelova, J, et al. (2005) In European Heart Journal 26(21). p.2325-2333
Abstract
Aims To describe clinical and demographic characteristics at baseline of a European cohort of adults with congenital heart disease (CHD) and to assess mortality and morbidity in a 5 year follow-up period. Methods and results Data collected as part of the Euro Heart Survey on adult CHD was analysed. This entailed information transcribed from the files of 4110 patients diagnosed with one of eight congenital heart conditions ('defects'), who consecutively visited the outpatient clinics of one of the participating centres in 1998. The patients were included retrospectively and followed until the end of 2003 for a median follow-up of 5.1 years. Notwithstanding their overall relatively good functional class and low mortality over the follow-up... (More)
Aims To describe clinical and demographic characteristics at baseline of a European cohort of adults with congenital heart disease (CHD) and to assess mortality and morbidity in a 5 year follow-up period. Methods and results Data collected as part of the Euro Heart Survey on adult CHD was analysed. This entailed information transcribed from the files of 4110 patients diagnosed with one of eight congenital heart conditions ('defects'), who consecutively visited the outpatient clinics of one of the participating centres in 1998. The patients were included retrospectively and followed until the end of 2003 for a median follow-up of 5.1 years. Notwithstanding their overall relatively good functional class and low mortality over the follow-up period, a considerable proportion of the patients had a history of endocarditis, arrhythmias, or vascular events. There were major differences between the eight defects, both in morbidity and regarding specific characteristics. Outcomes were worst in cyanotic defects and in the Fontan circulation, but a considerable proportion of the other patients also suffer from cardiac symptoms. In particular, arrhythmias are common. Conclusion The spectrum of adult CHD in Europe emerging from this survey is one of a predominantly young population with substantial morbidity but relatively low mortality in a 5 year period. (Less)
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Contribution to journal
publication status
published
subject
keywords
mortality, morbidity, adults, congenital heart disease, Euro Heart Survey, baseline characteristics
in
European Heart Journal
volume
26
issue
21
pages
2325 - 2333
publisher
Oxford University Press
external identifiers
  • wos:000232747900021
  • pmid:15996978
  • scopus:27544480369
ISSN
1522-9645
DOI
10.1093/eurheartj/ehi396
language
English
LU publication?
yes
id
a0a23367-b8cc-4714-ae19-880fd255949e (old id 218806)
date added to LUP
2007-09-21 13:53:16
date last changed
2017-11-12 03:58:15
@article{a0a23367-b8cc-4714-ae19-880fd255949e,
  abstract     = {Aims To describe clinical and demographic characteristics at baseline of a European cohort of adults with congenital heart disease (CHD) and to assess mortality and morbidity in a 5 year follow-up period. Methods and results Data collected as part of the Euro Heart Survey on adult CHD was analysed. This entailed information transcribed from the files of 4110 patients diagnosed with one of eight congenital heart conditions ('defects'), who consecutively visited the outpatient clinics of one of the participating centres in 1998. The patients were included retrospectively and followed until the end of 2003 for a median follow-up of 5.1 years. Notwithstanding their overall relatively good functional class and low mortality over the follow-up period, a considerable proportion of the patients had a history of endocarditis, arrhythmias, or vascular events. There were major differences between the eight defects, both in morbidity and regarding specific characteristics. Outcomes were worst in cyanotic defects and in the Fontan circulation, but a considerable proportion of the other patients also suffer from cardiac symptoms. In particular, arrhythmias are common. Conclusion The spectrum of adult CHD in Europe emerging from this survey is one of a predominantly young population with substantial morbidity but relatively low mortality in a 5 year period.},
  author       = {Engelfriet, P and Boersma, E and Oechslin, E and Tijssen, J and Gatzoulis, M A and Thilén, Ulf and Kaemmerer, H and Moons, P and Meijboom, F and Popelova, J and Laforest, V and Hirsch, R and Daliento, L and Thaulow, E and Mulder, B},
  issn         = {1522-9645},
  keyword      = {mortality,morbidity,adults,congenital heart disease,Euro Heart Survey,baseline characteristics},
  language     = {eng},
  number       = {21},
  pages        = {2325--2333},
  publisher    = {Oxford University Press},
  series       = {European Heart Journal},
  title        = {The spectrum of adult congenital heart disease in Europe: morbidity and mortality in a 5 year follow-up period - The Euro Heart Survey on adult congenital heart disease},
  url          = {http://dx.doi.org/10.1093/eurheartj/ehi396},
  volume       = {26},
  year         = {2005},
}