Osteolytic potential of triphenyl bismuth as an alternative contrast medium in acrylic bone cement
(2005) In Journal of Biomedical Materials Research. Part B - Applied Biomaterials 75B(1). p.64-73- Abstract
- Radiopaque cement containing barium sulfate causes significantly more bone resorption in vivo and in vitro than radiolucent cement. The aim of this study was to investigate the osteolytic potential of an alternative radiopaque agent, triphenyl bismuth (TPB). Bone cement particles containing various concentration of TPB (15 and 25 wt%) prepared by two methods, blending and dissolution, were added to monocytes in a bone resorption assay and the extent of lacunar resorption on dentine slices was determined. The results clearly show that cement particles containing TPB cause less bone resorption than cement particles containing barium sulfate. In addition, our results suggest that TPB prepared by dissolution in bone cement induces less... (More)
- Radiopaque cement containing barium sulfate causes significantly more bone resorption in vivo and in vitro than radiolucent cement. The aim of this study was to investigate the osteolytic potential of an alternative radiopaque agent, triphenyl bismuth (TPB). Bone cement particles containing various concentration of TPB (15 and 25 wt%) prepared by two methods, blending and dissolution, were added to monocytes in a bone resorption assay and the extent of lacunar resorption on dentine slices was determined. The results clearly show that cement particles containing TPB cause less bone resorption than cement particles containing barium sulfate. In addition, our results suggest that TPB prepared by dissolution in bone cement induces less osteolytic response than TPB-cement prepared by blending. The osteolysis in response to bone cement wear particles may therefore be reduced with TPB prepared using the blending technique. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/223113
- author
- Xu, H ; Abdulghani, Saba LU ; Behiri, J and Sabokbar, A
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- triphenyl bismuth, radiopacity, bone cement, bone resorption, osteoclast
- in
- Journal of Biomedical Materials Research. Part B - Applied Biomaterials
- volume
- 75B
- issue
- 1
- pages
- 64 - 73
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:16015616
- wos:000232168200009
- scopus:25844459980
- ISSN
- 1552-4981
- DOI
- 10.1002/jbm.b.30277
- language
- English
- LU publication?
- yes
- id
- 17d91963-37ff-47c7-9130-b4346368d576 (old id 223113)
- date added to LUP
- 2016-04-01 11:37:00
- date last changed
- 2022-01-26 07:43:01
@article{17d91963-37ff-47c7-9130-b4346368d576,
abstract = {{Radiopaque cement containing barium sulfate causes significantly more bone resorption in vivo and in vitro than radiolucent cement. The aim of this study was to investigate the osteolytic potential of an alternative radiopaque agent, triphenyl bismuth (TPB). Bone cement particles containing various concentration of TPB (15 and 25 wt%) prepared by two methods, blending and dissolution, were added to monocytes in a bone resorption assay and the extent of lacunar resorption on dentine slices was determined. The results clearly show that cement particles containing TPB cause less bone resorption than cement particles containing barium sulfate. In addition, our results suggest that TPB prepared by dissolution in bone cement induces less osteolytic response than TPB-cement prepared by blending. The osteolysis in response to bone cement wear particles may therefore be reduced with TPB prepared using the blending technique.}},
author = {{Xu, H and Abdulghani, Saba and Behiri, J and Sabokbar, A}},
issn = {{1552-4981}},
keywords = {{triphenyl bismuth; radiopacity; bone cement; bone resorption; osteoclast}},
language = {{eng}},
number = {{1}},
pages = {{64--73}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Journal of Biomedical Materials Research. Part B - Applied Biomaterials}},
title = {{Osteolytic potential of triphenyl bismuth as an alternative contrast medium in acrylic bone cement}},
url = {{http://dx.doi.org/10.1002/jbm.b.30277}},
doi = {{10.1002/jbm.b.30277}},
volume = {{75B}},
year = {{2005}},
}