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Revision 1 Size and position of the healthy meniscus, and its Correlation with sex, height, weight, and bone area- a cross-sectional study

Bloecker, Katja; Englund, Martin LU ; Wirth, Wolfgang; Hudelmaier, Martin; Burgkart, Rainer; Frobell, Richard LU and Eckstein, Felix (2011) In BMC Musculoskeletal Disorders 12.
Abstract
Background: Meniscus extrusion or hypertrophy may occur in knee osteoarthritis (OA). However, currently no data are available on the position and size of the meniscus in asymptomatic men and women with normal meniscus integrity. Methods: Three-dimensional coronal DESSwe MRIs were used to segment and quantitatively measure the size and position of the medial and lateral menisci, and their correlation with sex, height, weight, and tibial plateau area. 102 knees (40 male and 62 female) were drawn from the Osteoarthritis Initiative "non-exposed" reference cohort, including subjects without symptoms, radiographic signs, or risk factors for knee OA. Knees with MRI signs of meniscus lesions were excluded. Results: The tibial plateau area was... (More)
Background: Meniscus extrusion or hypertrophy may occur in knee osteoarthritis (OA). However, currently no data are available on the position and size of the meniscus in asymptomatic men and women with normal meniscus integrity. Methods: Three-dimensional coronal DESSwe MRIs were used to segment and quantitatively measure the size and position of the medial and lateral menisci, and their correlation with sex, height, weight, and tibial plateau area. 102 knees (40 male and 62 female) were drawn from the Osteoarthritis Initiative "non-exposed" reference cohort, including subjects without symptoms, radiographic signs, or risk factors for knee OA. Knees with MRI signs of meniscus lesions were excluded. Results: The tibial plateau area was significantly larger (p < 0.001) in male knees than in female ones (+23% medially; +28% laterally), as was total meniscus surface area (p < 0.001, +20% medially; +26% laterally). Ipsi-compartimental tibial plateau area was more strongly correlated with total meniscus surface area in men (r=.72 medially; r=.62 laterally) and women (r=.67; r=.75) than contra-compartimental or total tibial plateau area, body height or weight. The ratio of meniscus versus tibial plateau area was similar between men and women (p=0.22 medially; p=0.72 laterally). Tibial coverage by the meniscus was similar between men and women (50% medially; 58% laterally), but "physiological" medial meniscal extrusion was greater in women (1.83 +/- 1.06mm) than in men (1.24mm +/- 1.18mm; p=0.011). Conclusions: These data suggest that meniscus surface area strongly scales with (ipsilateral) tibial plateau area across both sexes, and that tibial coverage by the meniscus is similar between men and women. (Less)
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author
organization
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type
Contribution to journal
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published
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in
BMC Musculoskeletal Disorders
volume
12
publisher
BioMed Central
external identifiers
  • wos:000296971200002
  • scopus:80055011563
ISSN
1471-2474
DOI
10.1186/1471-2474-12-248
language
English
LU publication?
yes
id
ce522eaf-7ccf-4ca0-ab6a-da1f732b0e38 (old id 2253374)
date added to LUP
2011-12-20 13:29:03
date last changed
2017-06-18 03:51:07
@article{ce522eaf-7ccf-4ca0-ab6a-da1f732b0e38,
  abstract     = {Background: Meniscus extrusion or hypertrophy may occur in knee osteoarthritis (OA). However, currently no data are available on the position and size of the meniscus in asymptomatic men and women with normal meniscus integrity. Methods: Three-dimensional coronal DESSwe MRIs were used to segment and quantitatively measure the size and position of the medial and lateral menisci, and their correlation with sex, height, weight, and tibial plateau area. 102 knees (40 male and 62 female) were drawn from the Osteoarthritis Initiative "non-exposed" reference cohort, including subjects without symptoms, radiographic signs, or risk factors for knee OA. Knees with MRI signs of meniscus lesions were excluded. Results: The tibial plateau area was significantly larger (p &lt; 0.001) in male knees than in female ones (+23% medially; +28% laterally), as was total meniscus surface area (p &lt; 0.001, +20% medially; +26% laterally). Ipsi-compartimental tibial plateau area was more strongly correlated with total meniscus surface area in men (r=.72 medially; r=.62 laterally) and women (r=.67; r=.75) than contra-compartimental or total tibial plateau area, body height or weight. The ratio of meniscus versus tibial plateau area was similar between men and women (p=0.22 medially; p=0.72 laterally). Tibial coverage by the meniscus was similar between men and women (50% medially; 58% laterally), but "physiological" medial meniscal extrusion was greater in women (1.83 +/- 1.06mm) than in men (1.24mm +/- 1.18mm; p=0.011). Conclusions: These data suggest that meniscus surface area strongly scales with (ipsilateral) tibial plateau area across both sexes, and that tibial coverage by the meniscus is similar between men and women.},
  author       = {Bloecker, Katja and Englund, Martin and Wirth, Wolfgang and Hudelmaier, Martin and Burgkart, Rainer and Frobell, Richard and Eckstein, Felix},
  issn         = {1471-2474},
  language     = {eng},
  publisher    = {BioMed Central},
  series       = {BMC Musculoskeletal Disorders},
  title        = {Revision 1 Size and position of the healthy meniscus, and its Correlation with sex, height, weight, and bone area- a cross-sectional study},
  url          = {http://dx.doi.org/10.1186/1471-2474-12-248},
  volume       = {12},
  year         = {2011},
}