Advanced

Contrast-enhanced radiography by differential absorption, using a laser-produced X-ray source

Herrlin, K; Tillman, C; Gratz, M; Olsson, C; Pettersson, H; Svahn, G; Wahlström, Claes-Göran LU and Svanberg, Sune LU (1997) In Investigative Radiology 32(5). p.306-310
Abstract
RATIONALE AND OBJECTIVES. The authors evaluate the feasibility of differential imaging of contrast media, with division of individual pixel values obtained from digital images generated by characteristic radiation from a laser-produced plasma, bridging the K-absorption edge of the contrast agent. METHODS. Laser pulses from an ultrashort-pulse terawatt laser system were focused onto gadolinium and tantalum targets, creating a plasma from which characteristic radiation and Bremsstrahlung was emitted. The elements of the target were selected so the characteristic emission lines of one of the elements were below the K edge of the contrast agent and the emission lines of the other element above. A phantom with gadolinium and other elements in... (More)
RATIONALE AND OBJECTIVES. The authors evaluate the feasibility of differential imaging of contrast media, with division of individual pixel values obtained from digital images generated by characteristic radiation from a laser-produced plasma, bridging the K-absorption edge of the contrast agent. METHODS. Laser pulses from an ultrashort-pulse terawatt laser system were focused onto gadolinium and tantalum targets, creating a plasma from which characteristic radiation and Bremsstrahlung was emitted. The elements of the target were selected so the characteristic emission lines of one of the elements were below the K edge of the contrast agent and the emission lines of the other element above. A phantom with gadolinium and other elements in various concentrations was examined. One radiographic exposure was made using a gadolinium target source and a subsequent exposure using a tantalum source. Both images were recorded digitally and the transmission ratios calculated by division of the individual pixel values. RESULTS. When viewed separately, the two images of the test phantom appeared similar. In the differential image, only the gadolinium solutions were bright, reflecting a difference in attenuation between the two exposures. CONCLUSIONS. Element-specific radiographs can be obtained by differential imaging. When fully explored, the technique may allow for contrast-enhanced radiography with increased sensitivity and decreased contrast dose. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Investigative Radiology
volume
32
issue
5
pages
306 - 310
publisher
Lippincott Williams & Wilkins
external identifiers
  • scopus:0343471874
ISSN
0020-9996
language
English
LU publication?
yes
id
da408419-d7d9-40d5-b16d-40adc0a58c60 (old id 2258340)
alternative location
http://journals.lww.com/investigativeradiology/Abstract/1997/05000/Contrast_Enhanced_Radiography_by_Differential.9.aspx
date added to LUP
2012-02-27 12:30:16
date last changed
2017-01-01 07:34:01
@article{da408419-d7d9-40d5-b16d-40adc0a58c60,
  abstract     = {RATIONALE AND OBJECTIVES. The authors evaluate the feasibility of differential imaging of contrast media, with division of individual pixel values obtained from digital images generated by characteristic radiation from a laser-produced plasma, bridging the K-absorption edge of the contrast agent. METHODS. Laser pulses from an ultrashort-pulse terawatt laser system were focused onto gadolinium and tantalum targets, creating a plasma from which characteristic radiation and Bremsstrahlung was emitted. The elements of the target were selected so the characteristic emission lines of one of the elements were below the K edge of the contrast agent and the emission lines of the other element above. A phantom with gadolinium and other elements in various concentrations was examined. One radiographic exposure was made using a gadolinium target source and a subsequent exposure using a tantalum source. Both images were recorded digitally and the transmission ratios calculated by division of the individual pixel values. RESULTS. When viewed separately, the two images of the test phantom appeared similar. In the differential image, only the gadolinium solutions were bright, reflecting a difference in attenuation between the two exposures. CONCLUSIONS. Element-specific radiographs can be obtained by differential imaging. When fully explored, the technique may allow for contrast-enhanced radiography with increased sensitivity and decreased contrast dose.},
  author       = {Herrlin, K and Tillman, C and Gratz, M and Olsson, C and Pettersson, H and Svahn, G and Wahlström, Claes-Göran and Svanberg, Sune},
  issn         = {0020-9996},
  language     = {eng},
  number       = {5},
  pages        = {306--310},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {Investigative Radiology},
  title        = {Contrast-enhanced radiography by differential absorption, using a laser-produced X-ray source},
  volume       = {32},
  year         = {1997},
}