Elemental biological imaging by differential absorption with a laser-produced x-ray source
(1996) In Journal of the Optical Society of America B: Optical Physics 13(1). p.209-215- Abstract
- We demonstrate the novel application of hard x rays emitted by a laser-produced plasma for differential imaging of elements. An x-ray-emitting laser-produced plasma, obtained by the focusing of radiation from a 10-Hz terawatt laser, is used for biological imaging. The x-ray source can be arranged to yield characteristic x-ray emission lines with photon energies that bridge the K absorption edge of a chosen atomic species. One can obtain element-specific radiographs by recording transillumination images for different target materials on digital image plates and by subsequently subtracting or dividing the images. Successful phantom and experimental animal imaging are performed utilizing tantalum and gadolinium as target materials for the... (More)
- We demonstrate the novel application of hard x rays emitted by a laser-produced plasma for differential imaging of elements. An x-ray-emitting laser-produced plasma, obtained by the focusing of radiation from a 10-Hz terawatt laser, is used for biological imaging. The x-ray source can be arranged to yield characteristic x-ray emission lines with photon energies that bridge the K absorption edge of a chosen atomic species. One can obtain element-specific radiographs by recording transillumination images for different target materials on digital image plates and by subsequently subtracting or dividing the images. Successful phantom and experimental animal imaging are performed utilizing tantalum and gadolinium as target materials for the terawatt laser and gadolinium as the imaged contrast agent. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2259609
- author
- Tillman, C ; Mercer, I ; Svanberg, Sune LU and Herrlin, K
- organization
- publishing date
- 1996
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of the Optical Society of America B: Optical Physics
- volume
- 13
- issue
- 1
- pages
- 209 - 215
- publisher
- Optical Society of America
- external identifiers
-
- scopus:0030532382
- ISSN
- 0740-3224
- DOI
- 10.1364/JOSAB.13.000209
- language
- English
- LU publication?
- yes
- id
- eba4cc78-9d2a-453b-968d-d794417ace56 (old id 2259609)
- date added to LUP
- 2016-04-04 10:50:42
- date last changed
- 2022-04-23 23:42:04
@article{eba4cc78-9d2a-453b-968d-d794417ace56,
abstract = {{We demonstrate the novel application of hard x rays emitted by a laser-produced plasma for differential imaging of elements. An x-ray-emitting laser-produced plasma, obtained by the focusing of radiation from a 10-Hz terawatt laser, is used for biological imaging. The x-ray source can be arranged to yield characteristic x-ray emission lines with photon energies that bridge the K absorption edge of a chosen atomic species. One can obtain element-specific radiographs by recording transillumination images for different target materials on digital image plates and by subsequently subtracting or dividing the images. Successful phantom and experimental animal imaging are performed utilizing tantalum and gadolinium as target materials for the terawatt laser and gadolinium as the imaged contrast agent.}},
author = {{Tillman, C and Mercer, I and Svanberg, Sune and Herrlin, K}},
issn = {{0740-3224}},
language = {{eng}},
number = {{1}},
pages = {{209--215}},
publisher = {{Optical Society of America}},
series = {{Journal of the Optical Society of America B: Optical Physics}},
title = {{Elemental biological imaging by differential absorption with a laser-produced x-ray source}},
url = {{https://lup.lub.lu.se/search/files/5634359/2297664.pdf}},
doi = {{10.1364/JOSAB.13.000209}},
volume = {{13}},
year = {{1996}},
}