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Nocturia and Quality of Life: Results from the Boston Area Community Health Survey

Kupelian, Varant; Wei, John T.; O'Leary, Michael P.; Norgaard, Jens Peter LU ; Rosen, Raymond C. and McKinlay, John B. (2012) In European Urology 61(1). p.78-84
Abstract
Background: Nocturia, a common complaint in aging men and women, is frequently cited as the cause of nocturnal awakenings leading to sleep loss, daytime fatigue, and reduced quality of life (QOL). Objective: Investigate the association of nocturia with QOL and depressive symptoms among men and women. Design, setting, and participants: A population-based epidemiologic survey of urologic symptoms among persons aged 30-79 yr. A multistage stratified cluster sample design was used to randomly sample 5503 residents of Boston, MA, USA. Measurements: Nocturia was defined as a self-report of two or more voiding episodes nightly or having to get up to urinate more than once nightly "fairly often,'' "usually,'' or "almost always.'' QOL was assessed... (More)
Background: Nocturia, a common complaint in aging men and women, is frequently cited as the cause of nocturnal awakenings leading to sleep loss, daytime fatigue, and reduced quality of life (QOL). Objective: Investigate the association of nocturia with QOL and depressive symptoms among men and women. Design, setting, and participants: A population-based epidemiologic survey of urologic symptoms among persons aged 30-79 yr. A multistage stratified cluster sample design was used to randomly sample 5503 residents of Boston, MA, USA. Measurements: Nocturia was defined as a self-report of two or more voiding episodes nightly or having to get up to urinate more than once nightly "fairly often,'' "usually,'' or "almost always.'' QOL was assessed using the physical and mental health component scores of the 12-Item Short-Form Survey (SF-12). Depression was assessed using the Center for Epidemiological Studies Depression Scale. Multiple linear and logistic regression methods were used to model the nocturia and QOL association and to control for confounders. Results and limitations: Nocturia was associated with decreased SF-12 scores for both the physical and mental health components after multivariate adjustment. Nocturia was also associated with increased odds of depressive symptoms (men: adjusted odds ratio [OR]: 2.79; 95% confidence interval [CI], 1.81-4.31; women: adjusted OR: 1.80; 95% CI, 1.29-2.51). Among women who reported sleep interference due to urologic symptoms, nocturia was associated with a threefold increase in odds of depression. In this cross-sectional analysis, the temporal sequence of causality of the nocturia and depression association could not be assessed. Conclusions: Nocturia is associated with decreased QOL and with an increased prevalence of depressive symptoms in both men and women. (C) 2011 European Association of Urology. Published by Elsevier B.V. All rights reserved. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Nocturia, Quality of life, Depression, Epidemiology
in
European Urology
volume
61
issue
1
pages
78 - 84
publisher
Elsevier
external identifiers
  • wos:000297861800016
  • scopus:82255174908
ISSN
1873-7560
DOI
10.1016/j.eururo.2011.05.065
language
English
LU publication?
yes
id
061eee21-c460-4b5a-9442-fe9d8e9b83b2 (old id 2278962)
date added to LUP
2012-01-11 13:39:21
date last changed
2017-07-30 04:21:03
@article{061eee21-c460-4b5a-9442-fe9d8e9b83b2,
  abstract     = {Background: Nocturia, a common complaint in aging men and women, is frequently cited as the cause of nocturnal awakenings leading to sleep loss, daytime fatigue, and reduced quality of life (QOL). Objective: Investigate the association of nocturia with QOL and depressive symptoms among men and women. Design, setting, and participants: A population-based epidemiologic survey of urologic symptoms among persons aged 30-79 yr. A multistage stratified cluster sample design was used to randomly sample 5503 residents of Boston, MA, USA. Measurements: Nocturia was defined as a self-report of two or more voiding episodes nightly or having to get up to urinate more than once nightly "fairly often,'' "usually,'' or "almost always.'' QOL was assessed using the physical and mental health component scores of the 12-Item Short-Form Survey (SF-12). Depression was assessed using the Center for Epidemiological Studies Depression Scale. Multiple linear and logistic regression methods were used to model the nocturia and QOL association and to control for confounders. Results and limitations: Nocturia was associated with decreased SF-12 scores for both the physical and mental health components after multivariate adjustment. Nocturia was also associated with increased odds of depressive symptoms (men: adjusted odds ratio [OR]: 2.79; 95% confidence interval [CI], 1.81-4.31; women: adjusted OR: 1.80; 95% CI, 1.29-2.51). Among women who reported sleep interference due to urologic symptoms, nocturia was associated with a threefold increase in odds of depression. In this cross-sectional analysis, the temporal sequence of causality of the nocturia and depression association could not be assessed. Conclusions: Nocturia is associated with decreased QOL and with an increased prevalence of depressive symptoms in both men and women. (C) 2011 European Association of Urology. Published by Elsevier B.V. All rights reserved.},
  author       = {Kupelian, Varant and Wei, John T. and O'Leary, Michael P. and Norgaard, Jens Peter and Rosen, Raymond C. and McKinlay, John B.},
  issn         = {1873-7560},
  keyword      = {Nocturia,Quality of life,Depression,Epidemiology},
  language     = {eng},
  number       = {1},
  pages        = {78--84},
  publisher    = {Elsevier},
  series       = {European Urology},
  title        = {Nocturia and Quality of Life: Results from the Boston Area Community Health Survey},
  url          = {http://dx.doi.org/10.1016/j.eururo.2011.05.065},
  volume       = {61},
  year         = {2012},
}