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Age, bodyweight, smoking habits and the risk of severe osteoarthritis in the hip and knee in men

Jarvholm, B; Lewold, Stefan LU ; Malchau, H and Vingard, E (2005) In European Journal of Epidemiology 20(6). p.537-542
Abstract
Background: The objective of this study was to estimate the risk of severe osteoarthritis, with the need for arthroplasty, in the knee and/or hip according to body mass index (BMI) both within a normal range and in persons with high BMI. Furthermore, we wanted to study the significance of smoking. Methods: This study identifies male construction workers participating in a national health control program (n = 320,192). The incidence rate for joint replacement was found by matching with the Swedish hospital discharge register between 1987 and 1998. BMI and smoking habit was registered at the time of the health examination. Results: In total 1495 cases of osteoarthritis of the hip and 502 cases of osteoarthritis of the knee were identified... (More)
Background: The objective of this study was to estimate the risk of severe osteoarthritis, with the need for arthroplasty, in the knee and/or hip according to body mass index (BMI) both within a normal range and in persons with high BMI. Furthermore, we wanted to study the significance of smoking. Methods: This study identifies male construction workers participating in a national health control program (n = 320,192). The incidence rate for joint replacement was found by matching with the Swedish hospital discharge register between 1987 and 1998. BMI and smoking habit was registered at the time of the health examination. Results: In total 1495 cases of osteoarthritis of the hip and 502 cases of osteoarthritis of the knee were identified and included in this analysis. The incidence rate was found to increase linearly to the BMI even within low and,normal' BMI. The relative risk for osteoarthritis of the hip was more than two times higher in persons with a BMI of 20-24 than in men with a BMI 17-19. There was almost a doubling of the risk of severe knee 2 osteoarthritis with an increase in BMI of 5 kg/m(2). Smoker had a lower risk of osteoarthritis than non-smokers and ex-smokers. Conclusions: BMI is an important predictor of osteoarthritis even within normal BMI. A decreased risk of osteoarthritis of the hip was found in smokers, but the effect was weak compared to that of BMI or age. Contrary to studies of radiographic osteoarthritis our study indicates higher risk of hip than of knee osteoarthritis. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
joint, epidemiology, body mass index (BMI), construction workers, smoking, replacement
in
European Journal of Epidemiology
volume
20
issue
6
pages
537 - 542
publisher
Springer
external identifiers
  • pmid:16121763
  • wos:000231222900008
  • scopus:21644481365
ISSN
1573-7284
DOI
10.1007/s10654-005-4263-x
language
English
LU publication?
yes
id
7f507e12-3c78-4abf-acdf-3f41ce8f773c (old id 229284)
date added to LUP
2007-08-03 10:42:19
date last changed
2017-10-22 03:45:13
@article{7f507e12-3c78-4abf-acdf-3f41ce8f773c,
  abstract     = {Background: The objective of this study was to estimate the risk of severe osteoarthritis, with the need for arthroplasty, in the knee and/or hip according to body mass index (BMI) both within a normal range and in persons with high BMI. Furthermore, we wanted to study the significance of smoking. Methods: This study identifies male construction workers participating in a national health control program (n = 320,192). The incidence rate for joint replacement was found by matching with the Swedish hospital discharge register between 1987 and 1998. BMI and smoking habit was registered at the time of the health examination. Results: In total 1495 cases of osteoarthritis of the hip and 502 cases of osteoarthritis of the knee were identified and included in this analysis. The incidence rate was found to increase linearly to the BMI even within low and,normal' BMI. The relative risk for osteoarthritis of the hip was more than two times higher in persons with a BMI of 20-24 than in men with a BMI 17-19. There was almost a doubling of the risk of severe knee 2 osteoarthritis with an increase in BMI of 5 kg/m(2). Smoker had a lower risk of osteoarthritis than non-smokers and ex-smokers. Conclusions: BMI is an important predictor of osteoarthritis even within normal BMI. A decreased risk of osteoarthritis of the hip was found in smokers, but the effect was weak compared to that of BMI or age. Contrary to studies of radiographic osteoarthritis our study indicates higher risk of hip than of knee osteoarthritis.},
  author       = {Jarvholm, B and Lewold, Stefan and Malchau, H and Vingard, E},
  issn         = {1573-7284},
  keyword      = {joint,epidemiology,body mass index (BMI),construction workers,smoking,replacement},
  language     = {eng},
  number       = {6},
  pages        = {537--542},
  publisher    = {Springer},
  series       = {European Journal of Epidemiology},
  title        = {Age, bodyweight, smoking habits and the risk of severe osteoarthritis in the hip and knee in men},
  url          = {http://dx.doi.org/10.1007/s10654-005-4263-x},
  volume       = {20},
  year         = {2005},
}