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Echocardiographic prediction of patent ductus arteriosus in need of therapeutic intervention

Harling, S.; Pupp, Ingrid LU ; Baigi, A. and Pesonen, E. (2011) In Acta Pædiatrica 100(2). p.231-235
Abstract
Aim: To evaluate the efficacy of various echocardiographic markers in predicting a patent ductus arteriosus (PDA) in need of treatment. Methods: Forty-five preterm infants with a mean (SD) gestational age of 27.7 (1.9) weeks underwent echocardiography at a postnatal age of 24 +/- 6 and 72 +/- 6 h. Four echocardiographic markers were studied: ductus diameter, ductal flow Doppler curves, the left atrial to aortic root (LA/Ao) ratio and Doppler pixels representing ductal shunting. Results: Twenty-eight infants had a PDA with a detectable left-to-right shunt. Of these, 12 (43%) were treated for a shunt through the PDA. Ductal diameter was the most accurate echocardiographic marker when it came to predicting a significant shunt, with a... (More)
Aim: To evaluate the efficacy of various echocardiographic markers in predicting a patent ductus arteriosus (PDA) in need of treatment. Methods: Forty-five preterm infants with a mean (SD) gestational age of 27.7 (1.9) weeks underwent echocardiography at a postnatal age of 24 +/- 6 and 72 +/- 6 h. Four echocardiographic markers were studied: ductus diameter, ductal flow Doppler curves, the left atrial to aortic root (LA/Ao) ratio and Doppler pixels representing ductal shunting. Results: Twenty-eight infants had a PDA with a detectable left-to-right shunt. Of these, 12 (43%) were treated for a shunt through the PDA. Ductal diameter was the most accurate echocardiographic marker when it came to predicting a significant shunt, with a sensitivity of 89%, a specificity of 70%, a positive likelihood ratio of 2.97 and a negative likelihood ratio of 0.16 at the age of 72 h. The efficacy of the method at 72 h of age was 84%. The corresponding efficacy of the pulsatile Doppler curve was 72%, percentage of green colour pixels 63% and the LA/Ao ratio 53%. Conclusion: Ductus diameter appears to be the most important variable in determining the need for therapeutic intervention for PDA in preterm infants. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Colour Doppler echocardiography, Patent ductus arteriosus, Prediction, Very low birthweight infant
in
Acta Pædiatrica
volume
100
issue
2
pages
231 - 235
publisher
Wiley-Blackwell Publishing Ltd
external identifiers
  • wos:000285971100016
  • scopus:78651376375
ISSN
1651-2227
DOI
10.1111/j.1651-2227.2010.02027.x
language
English
LU publication?
yes
id
8fdbc5e4-bbdd-4fd5-9d46-6c1cc5c35dff (old id 2295900)
date added to LUP
2012-01-18 11:23:33
date last changed
2017-10-01 04:03:12
@article{8fdbc5e4-bbdd-4fd5-9d46-6c1cc5c35dff,
  abstract     = {Aim: To evaluate the efficacy of various echocardiographic markers in predicting a patent ductus arteriosus (PDA) in need of treatment. Methods: Forty-five preterm infants with a mean (SD) gestational age of 27.7 (1.9) weeks underwent echocardiography at a postnatal age of 24 +/- 6 and 72 +/- 6 h. Four echocardiographic markers were studied: ductus diameter, ductal flow Doppler curves, the left atrial to aortic root (LA/Ao) ratio and Doppler pixels representing ductal shunting. Results: Twenty-eight infants had a PDA with a detectable left-to-right shunt. Of these, 12 (43%) were treated for a shunt through the PDA. Ductal diameter was the most accurate echocardiographic marker when it came to predicting a significant shunt, with a sensitivity of 89%, a specificity of 70%, a positive likelihood ratio of 2.97 and a negative likelihood ratio of 0.16 at the age of 72 h. The efficacy of the method at 72 h of age was 84%. The corresponding efficacy of the pulsatile Doppler curve was 72%, percentage of green colour pixels 63% and the LA/Ao ratio 53%. Conclusion: Ductus diameter appears to be the most important variable in determining the need for therapeutic intervention for PDA in preterm infants.},
  author       = {Harling, S. and Pupp, Ingrid and Baigi, A. and Pesonen, E.},
  issn         = {1651-2227},
  keyword      = {Colour Doppler echocardiography,Patent ductus arteriosus,Prediction,Very low birthweight infant},
  language     = {eng},
  number       = {2},
  pages        = {231--235},
  publisher    = {Wiley-Blackwell Publishing Ltd},
  series       = {Acta Pædiatrica},
  title        = {Echocardiographic prediction of patent ductus arteriosus in need of therapeutic intervention},
  url          = {http://dx.doi.org/10.1111/j.1651-2227.2010.02027.x},
  volume       = {100},
  year         = {2011},
}