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The scotopic electroretinogram of the sugar glider related to histological features of its retina

Akula, James D.; Esdaille, Tricia M.; Caffé, Romeo LU and Naarendorp, Franklin (2011) In Journal of Comparative Physiology A 197(11). p.1043-1054
Abstract
The flash electroretinogram (ERG) was used to characterize the scotopic retinal function in a marsupial. Key parameter values of the a- and b-waves of adult male sugar gliders, Petaurus breviceps breviceps, elicited with ganzfeld flashes were determined under dark-and light-adapted conditions. Using standard histological methods, the thicknesses of the major layers of the retina were assessed to provide insight into the nature of the ERG responses. The ERG and histological results were compared to corresponding data for placental C57Bl/6 mice to establish whether the functional retinal specialization that underlies scotopic visual function in a marsupial parallels that of a placental mouse. The sensitivity of the a-wave assessed with the... (More)
The flash electroretinogram (ERG) was used to characterize the scotopic retinal function in a marsupial. Key parameter values of the a- and b-waves of adult male sugar gliders, Petaurus breviceps breviceps, elicited with ganzfeld flashes were determined under dark-and light-adapted conditions. Using standard histological methods, the thicknesses of the major layers of the retina were assessed to provide insight into the nature of the ERG responses. The ERG and histological results were compared to corresponding data for placental C57Bl/6 mice to establish whether the functional retinal specialization that underlies scotopic visual function in a marsupial parallels that of a placental mouse. The sensitivity of the a-wave assessed with the Lamb and Pugh (Invest Ophthalmol Vis Sci 47:5138-5152, 2006) "model" and that of the b-wave assessed with standard methods were lower in the sugar glider compared to the mouse. The thickness of the sugar glider retina was two-third of that of the mouse. The high-intensity flash ERG of the sugar glider substantially differed in shape from that of the mouse reflecting perhaps structural and functional differences between the two species at the level of the inner retina. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Rod photoreceptors, Rod ERG, Marsupials, Placental mammals, Rod, sensitivity
in
Journal of Comparative Physiology A
volume
197
issue
11
pages
1043 - 1054
publisher
Springer
external identifiers
  • wos:000298627200002
  • scopus:80255124837
ISSN
1432-1351
DOI
10.1007/s00359-011-0665-2
language
English
LU publication?
yes
id
efe954ac-79a1-4167-a451-c04402470ee9 (old id 2295955)
date added to LUP
2012-01-18 10:48:55
date last changed
2017-01-01 06:05:04
@article{efe954ac-79a1-4167-a451-c04402470ee9,
  abstract     = {The flash electroretinogram (ERG) was used to characterize the scotopic retinal function in a marsupial. Key parameter values of the a- and b-waves of adult male sugar gliders, Petaurus breviceps breviceps, elicited with ganzfeld flashes were determined under dark-and light-adapted conditions. Using standard histological methods, the thicknesses of the major layers of the retina were assessed to provide insight into the nature of the ERG responses. The ERG and histological results were compared to corresponding data for placental C57Bl/6 mice to establish whether the functional retinal specialization that underlies scotopic visual function in a marsupial parallels that of a placental mouse. The sensitivity of the a-wave assessed with the Lamb and Pugh (Invest Ophthalmol Vis Sci 47:5138-5152, 2006) "model" and that of the b-wave assessed with standard methods were lower in the sugar glider compared to the mouse. The thickness of the sugar glider retina was two-third of that of the mouse. The high-intensity flash ERG of the sugar glider substantially differed in shape from that of the mouse reflecting perhaps structural and functional differences between the two species at the level of the inner retina.},
  author       = {Akula, James D. and Esdaille, Tricia M. and Caffé, Romeo and Naarendorp, Franklin},
  issn         = {1432-1351},
  keyword      = {Rod photoreceptors,Rod ERG,Marsupials,Placental mammals,Rod,sensitivity},
  language     = {eng},
  number       = {11},
  pages        = {1043--1054},
  publisher    = {Springer},
  series       = {Journal of Comparative Physiology A},
  title        = {The scotopic electroretinogram of the sugar glider related to histological features of its retina},
  url          = {http://dx.doi.org/10.1007/s00359-011-0665-2},
  volume       = {197},
  year         = {2011},
}