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Antibiotic treatment of uncomplicated urinary tract infection in premenopausal women

Naber, Kurt G.; Wullt, Björn LU and Wagenlehner, Florian M. E. (2011) In International Journal of Antimicrobial Agents 38. p.21-35
Abstract
Uncomplicated urinary tract infections (UTIs) in otherwise healthy premenopausal women are one of the most frequent infections in the community. Therefore any improvement in management will have a high impact not only on the quality of life of the individual patient but also on the health system. In placebo-controlled studies antimicrobial treatment was significantly more effective than placebo, but on the other hand showed more adverse events. The choice of antibiotic depends on the spectrum and susceptibility patterns of the uropathogens, its effectiveness for this indication, its tolerability, its collateral effects and cost. After a systematic literature search, recommendations for empiric treatment of acute uncomplicated cystitis and... (More)
Uncomplicated urinary tract infections (UTIs) in otherwise healthy premenopausal women are one of the most frequent infections in the community. Therefore any improvement in management will have a high impact not only on the quality of life of the individual patient but also on the health system. In placebo-controlled studies antimicrobial treatment was significantly more effective than placebo, but on the other hand showed more adverse events. The choice of antibiotic depends on the spectrum and susceptibility patterns of the uropathogens, its effectiveness for this indication, its tolerability, its collateral effects and cost. After a systematic literature search, recommendations for empiric treatment of acute uncomplicated cystitis and acute uncomplicated pyelonephritis and for follow-up strategies were developed. (C) 2011 Elsevier B. V. and the International Society of Chemotherapy. All rights reserved. (Less)
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Contribution to journal
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keywords
Uncomplicated urinary tract infection, Cystitis, Pyelonephritis, Premenopausal women, Empiric therapy, Aminoglycosides, Ampicillin, Amoxicillin, Cephalosporins, Cefpodoxime, Ciprofloxacin, Cotrimoxazole, Fluoroquinolones, Fosfomycin, Levofloxacin, Nitrofurantoin, Ofloxacin, Pivmecillinam, Trimethoprim
in
International Journal of Antimicrobial Agents
volume
38
pages
21 - 35
publisher
Elsevier
external identifiers
  • wos:000298141200004
  • scopus:82655172899
ISSN
1872-7913
DOI
10.1016/j.ijantimicag.2011.09.003
language
English
LU publication?
yes
id
085acc0a-d9b8-4539-8311-d0e618c41b7f (old id 2333130)
date added to LUP
2012-02-01 07:36:59
date last changed
2017-05-28 03:20:39
@article{085acc0a-d9b8-4539-8311-d0e618c41b7f,
  abstract     = {Uncomplicated urinary tract infections (UTIs) in otherwise healthy premenopausal women are one of the most frequent infections in the community. Therefore any improvement in management will have a high impact not only on the quality of life of the individual patient but also on the health system. In placebo-controlled studies antimicrobial treatment was significantly more effective than placebo, but on the other hand showed more adverse events. The choice of antibiotic depends on the spectrum and susceptibility patterns of the uropathogens, its effectiveness for this indication, its tolerability, its collateral effects and cost. After a systematic literature search, recommendations for empiric treatment of acute uncomplicated cystitis and acute uncomplicated pyelonephritis and for follow-up strategies were developed. (C) 2011 Elsevier B. V. and the International Society of Chemotherapy. All rights reserved.},
  author       = {Naber, Kurt G. and Wullt, Björn and Wagenlehner, Florian M. E.},
  issn         = {1872-7913},
  keyword      = {Uncomplicated urinary tract infection,Cystitis,Pyelonephritis,Premenopausal women,Empiric therapy,Aminoglycosides,Ampicillin,Amoxicillin,Cephalosporins,Cefpodoxime,Ciprofloxacin,Cotrimoxazole,Fluoroquinolones,Fosfomycin,Levofloxacin,Nitrofurantoin,Ofloxacin,Pivmecillinam,Trimethoprim},
  language     = {eng},
  pages        = {21--35},
  publisher    = {Elsevier},
  series       = {International Journal of Antimicrobial Agents},
  title        = {Antibiotic treatment of uncomplicated urinary tract infection in premenopausal women},
  url          = {http://dx.doi.org/10.1016/j.ijantimicag.2011.09.003},
  volume       = {38},
  year         = {2011},
}