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Clinicians’ use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors : an international survey

Brédart, Anne; Kop, Jean Luc; Antoniou, Antonis C.; Cunningham, Alex P.; de Pauw, Antoine; Tischkowitz, Marc; Ehrencrona, Hans LU ; Schmidt, Marjanka K.; Dolbeault, Sylvie and Rhiem, Kerstin, et al. (2018) In Journal of Community Genetics p.1-11
Abstract

The BOADICEA breast cancer (BC) risk assessment model and its associated Web Application v3 (BWA) tool are being extended to incorporate additional genetic and non-genetic BC risk factors. From an online survey through the BOADICEA website and UK, Dutch, French and Swedish national genetic societies, we explored the relationships between the usage frequencies of the BWA and six other common BC risk assessment tools and respondents’ perceived importance of BC risk factors. Respondents (N = 443) varied in age, country and clinical seniority but comprised mainly genetics health professionals (82%) and BWA users (93%). Oncology professionals perceived reproductive, hormonal (exogenous) and lifestyle BC risk factors as more important in BC... (More)

The BOADICEA breast cancer (BC) risk assessment model and its associated Web Application v3 (BWA) tool are being extended to incorporate additional genetic and non-genetic BC risk factors. From an online survey through the BOADICEA website and UK, Dutch, French and Swedish national genetic societies, we explored the relationships between the usage frequencies of the BWA and six other common BC risk assessment tools and respondents’ perceived importance of BC risk factors. Respondents (N = 443) varied in age, country and clinical seniority but comprised mainly genetics health professionals (82%) and BWA users (93%). Oncology professionals perceived reproductive, hormonal (exogenous) and lifestyle BC risk factors as more important in BC risk assessment compared to genetics professionals (p values < 0.05 to 0.0001). BWA was used more frequently by respondents who gave high weight to breast tumour pathology and low weight to personal BC history as BC risk factors. BWA use was positively related to the weight given to hormonal BC risk factors. The importance attributed to lifestyle and BMI BC risk factors was not associated with the use of BWA or any of the other tools. Next version of the BWA encompassing additional BC risk factors will facilitate more comprehensive BC risk assessment in genetics and oncology practice.

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keywords
BOADICEA, Breast cancer risk assessment, Clinical practice, Factors, Survey, Tools
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Journal of Community Genetics
pages
11 pages
publisher
Springer
external identifiers
  • scopus:85045140058
ISSN
1868-310X
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English
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yes
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23364c58-657f-491a-abb6-aba1eb6988ed
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2018-04-20 13:50:57
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2018-05-29 12:23:51
@article{23364c58-657f-491a-abb6-aba1eb6988ed,
  abstract     = {<p>The BOADICEA breast cancer (BC) risk assessment model and its associated Web Application v3 (BWA) tool are being extended to incorporate additional genetic and non-genetic BC risk factors. From an online survey through the BOADICEA website and UK, Dutch, French and Swedish national genetic societies, we explored the relationships between the usage frequencies of the BWA and six other common BC risk assessment tools and respondents’ perceived importance of BC risk factors. Respondents (N = 443) varied in age, country and clinical seniority but comprised mainly genetics health professionals (82%) and BWA users (93%). Oncology professionals perceived reproductive, hormonal (exogenous) and lifestyle BC risk factors as more important in BC risk assessment compared to genetics professionals (p values &lt; 0.05 to 0.0001). BWA was used more frequently by respondents who gave high weight to breast tumour pathology and low weight to personal BC history as BC risk factors. BWA use was positively related to the weight given to hormonal BC risk factors. The importance attributed to lifestyle and BMI BC risk factors was not associated with the use of BWA or any of the other tools. Next version of the BWA encompassing additional BC risk factors will facilitate more comprehensive BC risk assessment in genetics and oncology practice.</p>},
  author       = {Brédart, Anne and Kop, Jean Luc and Antoniou, Antonis C. and Cunningham, Alex P. and de Pauw, Antoine and Tischkowitz, Marc and Ehrencrona, Hans and Schmidt, Marjanka K. and Dolbeault, Sylvie and Rhiem, Kerstin and Easton, Douglas F. and Devilee, Peter and Stoppa-Lyonnet, Dominique and Schmutlzer, Rita},
  issn         = {1868-310X},
  keyword      = {BOADICEA,Breast cancer risk assessment,Clinical practice,Factors,Survey,Tools},
  language     = {eng},
  month        = {03},
  pages        = {1--11},
  publisher    = {Springer},
  series       = {Journal of Community Genetics},
  title        = {Clinicians’ use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors : an international survey},
  url          = {http://dx.doi.org/},
  year         = {2018},
}