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Guiding motor-propelled molecules with nanoscale precision through silanized bi-channel structures

Bunk, Richard LU ; Sundberg, M; Mansson, A; Nicholls, IA; Omling, Pär LU ; Tagerud, S and Montelius, Lars LU (2005) In Nanotechnology 16(6). p.710-717
Abstract
We report on the design and fabrication of a channel structure for high precision guidance and achieving excellent confinement properties for motor-propelled molecular shuttles. The techniques used to manufacture the channel structure are mainly e-beam lithography and selective monolayer functionalization. The structure consists of two lateral layers of concentric channels on a SiO2 surface made biocompatible with the molecular motors. The quality and advantages of the design are demonstrated by experiments using the motor proteins actin and myosin. The special channel geometry leads to stable biochemical conditions with full motor protein functionality. ATP is sufficiently supplied to all parts of the structure by dedicated service... (More)
We report on the design and fabrication of a channel structure for high precision guidance and achieving excellent confinement properties for motor-propelled molecular shuttles. The techniques used to manufacture the channel structure are mainly e-beam lithography and selective monolayer functionalization. The structure consists of two lateral layers of concentric channels on a SiO2 surface made biocompatible with the molecular motors. The quality and advantages of the design are demonstrated by experiments using the motor proteins actin and myosin. The special channel geometry leads to stable biochemical conditions with full motor protein functionality. ATP is sufficiently supplied to all parts of the structure by dedicated service channels, as is the venting of ADP and P-i (inorganic phosphorus). Channels of different widths (100-700 nm) and shapes are fabricated and measurements made on them. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Nanotechnology
volume
16
issue
6
pages
710 - 717
publisher
IOP Publishing
external identifiers
  • wos:000230144700014
  • scopus:18744380653
ISSN
0957-4484
DOI
10.1088/0957-4484/16/6/014
language
English
LU publication?
yes
id
55b9c1be-1b9e-4021-9c32-0642241d1750 (old id 233742)
date added to LUP
2007-08-14 08:51:30
date last changed
2017-04-09 03:46:01
@article{55b9c1be-1b9e-4021-9c32-0642241d1750,
  abstract     = {We report on the design and fabrication of a channel structure for high precision guidance and achieving excellent confinement properties for motor-propelled molecular shuttles. The techniques used to manufacture the channel structure are mainly e-beam lithography and selective monolayer functionalization. The structure consists of two lateral layers of concentric channels on a SiO2 surface made biocompatible with the molecular motors. The quality and advantages of the design are demonstrated by experiments using the motor proteins actin and myosin. The special channel geometry leads to stable biochemical conditions with full motor protein functionality. ATP is sufficiently supplied to all parts of the structure by dedicated service channels, as is the venting of ADP and P-i (inorganic phosphorus). Channels of different widths (100-700 nm) and shapes are fabricated and measurements made on them.},
  author       = {Bunk, Richard and Sundberg, M and Mansson, A and Nicholls, IA and Omling, Pär and Tagerud, S and Montelius, Lars},
  issn         = {0957-4484},
  language     = {eng},
  number       = {6},
  pages        = {710--717},
  publisher    = {IOP Publishing},
  series       = {Nanotechnology},
  title        = {Guiding motor-propelled molecules with nanoscale precision through silanized bi-channel structures},
  url          = {http://dx.doi.org/10.1088/0957-4484/16/6/014},
  volume       = {16},
  year         = {2005},
}