Vibratory perception threshold in young and middle-aged patients at high risk of knee osteoarthritis compared to controls
(2012) In Arthritis Care and Research 64(1). p.144-148- Abstract
- Objective Vibratory perception threshold (VPT) is impaired in patients with knee osteoarthritis (OA). It is, however, not known if sensory deficits precede or follow as a consequence of OA. The aim of this study was to investigate VPT in 2 independent groups of patients with high risk of future OA (young anterior cruciate ligament [ACL]-injured patients and middle-aged meniscectomized patients) and compare them to age-matched controls. Methods. VPT was assessed at the medial malleolus (MM) and medial femoral condyle (MFC) in 2 independent groups of patients and matched controls: ACL- injured patients (n = 39, mean +/- SD age 24.0 +/- 5.2 years, mean +/- SD BMI 24.0 +/- 2.9 kg/m(2), mean +/- SD time since injury 21.9 +/- 21.6 months) and... (More)
- Objective Vibratory perception threshold (VPT) is impaired in patients with knee osteoarthritis (OA). It is, however, not known if sensory deficits precede or follow as a consequence of OA. The aim of this study was to investigate VPT in 2 independent groups of patients with high risk of future OA (young anterior cruciate ligament [ACL]-injured patients and middle-aged meniscectomized patients) and compare them to age-matched controls. Methods. VPT was assessed at the medial malleolus (MM) and medial femoral condyle (MFC) in 2 independent groups of patients and matched controls: ACL- injured patients (n = 39, mean +/- SD age 24.0 +/- 5.2 years, mean +/- SD BMI 24.0 +/- 2.9 kg/m(2), mean +/- SD time since injury 21.9 +/- 21.6 months) and controls (n = 28, mean +/- SD age 25.6 +/- 4.4 years, mean +/- SD BMI 23.6 +/- 2.2 kg/m(2)), and meniscectomized patients (n = 22, mean +/- SD age 49.6 +/- 4.8 years, mean +/- SD BMI 24.7 +/- 2.7 kg/m(2), mean +/- SD time since surgery 49.6 +/- 5.0 months) and controls (n = 25, mean +/- SD age 49.4 +/- 5.2 years, mean +/- SD BMI 25.2 +/- 4.9 kg/m(2)). Results. ACL- injured patients had a better VPT than controls at the MM (P = 0.030), which persisted after adjusting for age and sex (P = 0.034). At the MFC, there was a similar trend in favor of ACL injured patients (unadjusted P = 0.093, adjusted P = 0.122). No differences were seen in VPT at theMMbetween meniscectomized patients and controls, whereas there was a tendency for better VPT in meniscectomized patients at the MFC (unadjusted P = 0.085, adjusted P = 0.092). Conclusion. Impaired vibratory sensation could not be confirmed in 2 independent groups of patients compared to age-matched controls, suggesting that impaired vibratory sense is not present in knee- injured patients at high risk or in the very early phase of knee OA. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2362509
- author
- Thorlund, Jonas Bloch ; Shakoor, Najia ; Ageberg, Eva LU ; Sandal, Louise Fleng ; Block, Joel A. and Roos, Ewa LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Arthritis Care and Research
- volume
- 64
- issue
- 1
- pages
- 144 - 148
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000298536700022
- scopus:84856879040
- pmid:21905255
- ISSN
- 2151-4658
- DOI
- 10.1002/acr.20624
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Physiotherapy (Closed 2012) (013042000), Department of Orthopaedics (Lund) (013028000)
- id
- f607b43f-c09c-4414-887e-19381f83c1bb (old id 2362509)
- date added to LUP
- 2016-04-01 10:19:29
- date last changed
- 2022-01-25 22:07:27
@article{f607b43f-c09c-4414-887e-19381f83c1bb, abstract = {{Objective Vibratory perception threshold (VPT) is impaired in patients with knee osteoarthritis (OA). It is, however, not known if sensory deficits precede or follow as a consequence of OA. The aim of this study was to investigate VPT in 2 independent groups of patients with high risk of future OA (young anterior cruciate ligament [ACL]-injured patients and middle-aged meniscectomized patients) and compare them to age-matched controls. Methods. VPT was assessed at the medial malleolus (MM) and medial femoral condyle (MFC) in 2 independent groups of patients and matched controls: ACL- injured patients (n = 39, mean +/- SD age 24.0 +/- 5.2 years, mean +/- SD BMI 24.0 +/- 2.9 kg/m(2), mean +/- SD time since injury 21.9 +/- 21.6 months) and controls (n = 28, mean +/- SD age 25.6 +/- 4.4 years, mean +/- SD BMI 23.6 +/- 2.2 kg/m(2)), and meniscectomized patients (n = 22, mean +/- SD age 49.6 +/- 4.8 years, mean +/- SD BMI 24.7 +/- 2.7 kg/m(2), mean +/- SD time since surgery 49.6 +/- 5.0 months) and controls (n = 25, mean +/- SD age 49.4 +/- 5.2 years, mean +/- SD BMI 25.2 +/- 4.9 kg/m(2)). Results. ACL- injured patients had a better VPT than controls at the MM (P = 0.030), which persisted after adjusting for age and sex (P = 0.034). At the MFC, there was a similar trend in favor of ACL injured patients (unadjusted P = 0.093, adjusted P = 0.122). No differences were seen in VPT at theMMbetween meniscectomized patients and controls, whereas there was a tendency for better VPT in meniscectomized patients at the MFC (unadjusted P = 0.085, adjusted P = 0.092). Conclusion. Impaired vibratory sensation could not be confirmed in 2 independent groups of patients compared to age-matched controls, suggesting that impaired vibratory sense is not present in knee- injured patients at high risk or in the very early phase of knee OA.}}, author = {{Thorlund, Jonas Bloch and Shakoor, Najia and Ageberg, Eva and Sandal, Louise Fleng and Block, Joel A. and Roos, Ewa}}, issn = {{2151-4658}}, language = {{eng}}, number = {{1}}, pages = {{144--148}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Arthritis Care and Research}}, title = {{Vibratory perception threshold in young and middle-aged patients at high risk of knee osteoarthritis compared to controls}}, url = {{http://dx.doi.org/10.1002/acr.20624}}, doi = {{10.1002/acr.20624}}, volume = {{64}}, year = {{2012}}, }