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Familial factors in anorexia nervosa: a community-based study

Wentz Nilsson, Elisabet; Gillberg, Christopher and Råstam, Maria LU (1998) In Comprehensive Psychiatry 39(6). p.392-399
Abstract
A group of 51 cases with teenage anorexia nervosa (AN; including a total population of cases from one birth cohort) were compared with a sex-, age-, and school-matched group of 51 cases on familial factors. The subjects were examined at age 16 and 21 years. In the first study, mothers of both groups were interviewed regarding physical and psychiatric disorders among first-degree relatives. In the followup study, the subjects were interviewed according to the same structured interview schedule. The data from these interviews were deidentified, and case notes were prepared by a clinician blind to group status. The randomly assorted case notes were then submitted to an experienced psychiatrist who also was blind to group status. There were... (More)
A group of 51 cases with teenage anorexia nervosa (AN; including a total population of cases from one birth cohort) were compared with a sex-, age-, and school-matched group of 51 cases on familial factors. The subjects were examined at age 16 and 21 years. In the first study, mothers of both groups were interviewed regarding physical and psychiatric disorders among first-degree relatives. In the followup study, the subjects were interviewed according to the same structured interview schedule. The data from these interviews were deidentified, and case notes were prepared by a clinician blind to group status. The randomly assorted case notes were then submitted to an experienced psychiatrist who also was blind to group status. There were more relatives with a history and symptoms suggestive of pervasive developmental disorders (PDD) and major depression in the AN group. There was also significantly more death in first-degree relatives of anorexia nervosa cases. In respect to many axis I DSM-IV diagnoses, including eating disorders and substance abuse, there were no significant differences across groups. Instead we found PDD symptoms, major depression, and death in first-degree relatives to be important in the AN group. (Less)
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author
publishing date
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Contribution to journal
publication status
published
subject
in
Comprehensive Psychiatry
volume
39
issue
6
pages
392 - 399
publisher
Elsevier
external identifiers
  • scopus:0031724895
ISSN
0010-440X
language
English
LU publication?
no
id
2b16f4d4-af81-4f70-beb0-60013489c62c (old id 2373215)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/9829148
http://www.sciencedirect.com/science/article/pii/S0010440X98900530
date added to LUP
2013-05-07 15:31:31
date last changed
2017-04-02 04:22:16
@article{2b16f4d4-af81-4f70-beb0-60013489c62c,
  abstract     = {A group of 51 cases with teenage anorexia nervosa (AN; including a total population of cases from one birth cohort) were compared with a sex-, age-, and school-matched group of 51 cases on familial factors. The subjects were examined at age 16 and 21 years. In the first study, mothers of both groups were interviewed regarding physical and psychiatric disorders among first-degree relatives. In the followup study, the subjects were interviewed according to the same structured interview schedule. The data from these interviews were deidentified, and case notes were prepared by a clinician blind to group status. The randomly assorted case notes were then submitted to an experienced psychiatrist who also was blind to group status. There were more relatives with a history and symptoms suggestive of pervasive developmental disorders (PDD) and major depression in the AN group. There was also significantly more death in first-degree relatives of anorexia nervosa cases. In respect to many axis I DSM-IV diagnoses, including eating disorders and substance abuse, there were no significant differences across groups. Instead we found PDD symptoms, major depression, and death in first-degree relatives to be important in the AN group.},
  author       = {Wentz Nilsson, Elisabet and Gillberg, Christopher and Råstam, Maria},
  issn         = {0010-440X},
  language     = {eng},
  number       = {6},
  pages        = {392--399},
  publisher    = {Elsevier},
  series       = {Comprehensive Psychiatry},
  title        = {Familial factors in anorexia nervosa: a community-based study},
  volume       = {39},
  year         = {1998},
}