Effective treatment of experimental acute otitis media by application of volatile fluids into the ear canal
(2005) In Journal of Infectious Diseases 191(11). p.1876-1880- Abstract
- Essential oils are volatile and can have good antimicrobial activity. We compared the effects of oil of basil ( Ocimum basilicum) and essential oil components ( thymol, carvacrol, and salicylaldehyde) to those of a placebo when placed in the ear canal of rats with experimental acute otitis media caused by pneumococci or Haemophilus influenzae. Progress was monitored by otomicroscopic examination and middle ear cultures. The treatment with oil of basil or essential oil components cured or healed 56%-81% of rats infected with H. influenzae and 6%-75% of rats infected with pneumococci, compared with 5.6%-6% of rats in the placebo group. Essential oils or their components placed in the ear canal can provide effective treatment of acute otitis... (More)
- Essential oils are volatile and can have good antimicrobial activity. We compared the effects of oil of basil ( Ocimum basilicum) and essential oil components ( thymol, carvacrol, and salicylaldehyde) to those of a placebo when placed in the ear canal of rats with experimental acute otitis media caused by pneumococci or Haemophilus influenzae. Progress was monitored by otomicroscopic examination and middle ear cultures. The treatment with oil of basil or essential oil components cured or healed 56%-81% of rats infected with H. influenzae and 6%-75% of rats infected with pneumococci, compared with 5.6%-6% of rats in the placebo group. Essential oils or their components placed in the ear canal can provide effective treatment of acute otitis media. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/240494
- author
- Kristinsson, K G ; Magnusdottir, Anna Björk LU ; Petersen, H and Hermansson, Ann LU
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Infectious Diseases
- volume
- 191
- issue
- 11
- pages
- 1876 - 1880
- publisher
- Oxford University Press
- external identifiers
-
- pmid:15871121
- wos:000228881100014
- scopus:18944384699
- ISSN
- 1537-6613
- DOI
- 10.1086/430003
- language
- English
- LU publication?
- yes
- id
- 8e8f710a-37f4-46ec-9e45-a01f23a487ba (old id 240494)
- date added to LUP
- 2016-04-01 16:03:17
- date last changed
- 2022-01-28 08:55:23
@article{8e8f710a-37f4-46ec-9e45-a01f23a487ba, abstract = {{Essential oils are volatile and can have good antimicrobial activity. We compared the effects of oil of basil ( Ocimum basilicum) and essential oil components ( thymol, carvacrol, and salicylaldehyde) to those of a placebo when placed in the ear canal of rats with experimental acute otitis media caused by pneumococci or Haemophilus influenzae. Progress was monitored by otomicroscopic examination and middle ear cultures. The treatment with oil of basil or essential oil components cured or healed 56%-81% of rats infected with H. influenzae and 6%-75% of rats infected with pneumococci, compared with 5.6%-6% of rats in the placebo group. Essential oils or their components placed in the ear canal can provide effective treatment of acute otitis media.}}, author = {{Kristinsson, K G and Magnusdottir, Anna Björk and Petersen, H and Hermansson, Ann}}, issn = {{1537-6613}}, language = {{eng}}, number = {{11}}, pages = {{1876--1880}}, publisher = {{Oxford University Press}}, series = {{Journal of Infectious Diseases}}, title = {{Effective treatment of experimental acute otitis media by application of volatile fluids into the ear canal}}, url = {{http://dx.doi.org/10.1086/430003}}, doi = {{10.1086/430003}}, volume = {{191}}, year = {{2005}}, }