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Effective treatment of experimental acute otitis media by application of volatile fluids into the ear canal

Kristinsson, K G; Magnusdottir, Anna Björk LU ; Petersen, H and Hermansson, Ann LU (2005) In Journal of Infectious Diseases 191(11). p.1876-1880
Abstract
Essential oils are volatile and can have good antimicrobial activity. We compared the effects of oil of basil ( Ocimum basilicum) and essential oil components ( thymol, carvacrol, and salicylaldehyde) to those of a placebo when placed in the ear canal of rats with experimental acute otitis media caused by pneumococci or Haemophilus influenzae. Progress was monitored by otomicroscopic examination and middle ear cultures. The treatment with oil of basil or essential oil components cured or healed 56%-81% of rats infected with H. influenzae and 6%-75% of rats infected with pneumococci, compared with 5.6%-6% of rats in the placebo group. Essential oils or their components placed in the ear canal can provide effective treatment of acute otitis... (More)
Essential oils are volatile and can have good antimicrobial activity. We compared the effects of oil of basil ( Ocimum basilicum) and essential oil components ( thymol, carvacrol, and salicylaldehyde) to those of a placebo when placed in the ear canal of rats with experimental acute otitis media caused by pneumococci or Haemophilus influenzae. Progress was monitored by otomicroscopic examination and middle ear cultures. The treatment with oil of basil or essential oil components cured or healed 56%-81% of rats infected with H. influenzae and 6%-75% of rats infected with pneumococci, compared with 5.6%-6% of rats in the placebo group. Essential oils or their components placed in the ear canal can provide effective treatment of acute otitis media. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Infectious Diseases
volume
191
issue
11
pages
1876 - 1880
publisher
Oxford University Press
external identifiers
  • pmid:15871121
  • wos:000228881100014
  • scopus:18944384699
ISSN
1537-6613
DOI
10.1086/430003
language
English
LU publication?
yes
id
8e8f710a-37f4-46ec-9e45-a01f23a487ba (old id 240494)
date added to LUP
2007-08-10 14:21:12
date last changed
2017-01-01 06:54:17
@article{8e8f710a-37f4-46ec-9e45-a01f23a487ba,
  abstract     = {Essential oils are volatile and can have good antimicrobial activity. We compared the effects of oil of basil ( Ocimum basilicum) and essential oil components ( thymol, carvacrol, and salicylaldehyde) to those of a placebo when placed in the ear canal of rats with experimental acute otitis media caused by pneumococci or Haemophilus influenzae. Progress was monitored by otomicroscopic examination and middle ear cultures. The treatment with oil of basil or essential oil components cured or healed 56%-81% of rats infected with H. influenzae and 6%-75% of rats infected with pneumococci, compared with 5.6%-6% of rats in the placebo group. Essential oils or their components placed in the ear canal can provide effective treatment of acute otitis media.},
  author       = {Kristinsson, K G and Magnusdottir, Anna Björk and Petersen, H and Hermansson, Ann},
  issn         = {1537-6613},
  language     = {eng},
  number       = {11},
  pages        = {1876--1880},
  publisher    = {Oxford University Press},
  series       = {Journal of Infectious Diseases},
  title        = {Effective treatment of experimental acute otitis media by application of volatile fluids into the ear canal},
  url          = {http://dx.doi.org/10.1086/430003},
  volume       = {191},
  year         = {2005},
}