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Heart Rate Variability in Children With Fontan Circulation: Lateral Tunnel and Extracardiac Conduit

Dahlqvist, Jenny Alenius; Karlsson, Marcus; Wiklund, Urban; Hornsten, Rolf; Stromvall-Larsson, Eva; Berggren, Hakan; Hanséus, Katarina LU ; Johansson, Sune LU and Rydberg, Annika (2012) In Pediatric Cardiology 33(2). p.307-315
Abstract
The technique in Fontan surgery has developed from the lateral tunnel (LT) toward the extracardiac conduit (EC) used to reduce long-term complications such as atrial arrhythmia and sinus node dysfunction. Heart rate variability (HRV) examines cardiac nervous activity controlling the sinus node. This study aimed to investigate HRV in a cohort of children with univentricular hearts, focusing on the relation between HRV and surgical procedure. For 112 children with Fontan circulation, HRV was analyzed using power spectral analysis. Spectral power was determined in three regions: very-low-frequency (VLF), low-frequency (LF), and high-frequency (HF) regions. Patients were compared with 66 healthy controls subject. Patients with LT were compared... (More)
The technique in Fontan surgery has developed from the lateral tunnel (LT) toward the extracardiac conduit (EC) used to reduce long-term complications such as atrial arrhythmia and sinus node dysfunction. Heart rate variability (HRV) examines cardiac nervous activity controlling the sinus node. This study aimed to investigate HRV in a cohort of children with univentricular hearts, focusing on the relation between HRV and surgical procedure. For 112 children with Fontan circulation, HRV was analyzed using power spectral analysis. Spectral power was determined in three regions: very-low-frequency (VLF), low-frequency (LF), and high-frequency (HF) regions. Patients were compared with 66 healthy controls subject. Patients with LT were compared with patients who had EC. The children with Fontan circulation showed a significantly reduced HRV including total power (P < 0.0001), VLF (P < 0.0001), LF (P < 0.0001), and HF (P = 0.001) compared with the control subjects. The LT and EC patients did not differ significantly. Reduced HRV was found in both the LT and EC patients. In terms of HRV reduction, EC was not superior to LT. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Extracardiac conduit, Fontan circulation, Heart rate variability, Lateral tunnel
in
Pediatric Cardiology
volume
33
issue
2
pages
307 - 315
publisher
Springer
external identifiers
  • wos:000299505500016
  • scopus:84862270116
ISSN
0172-0643
DOI
10.1007/s00246-011-0126-2
language
English
LU publication?
yes
id
7a10e813-f867-44ce-87dc-7d67695cf9e4 (old id 2416301)
date added to LUP
2012-04-02 09:46:09
date last changed
2017-06-11 03:16:31
@article{7a10e813-f867-44ce-87dc-7d67695cf9e4,
  abstract     = {The technique in Fontan surgery has developed from the lateral tunnel (LT) toward the extracardiac conduit (EC) used to reduce long-term complications such as atrial arrhythmia and sinus node dysfunction. Heart rate variability (HRV) examines cardiac nervous activity controlling the sinus node. This study aimed to investigate HRV in a cohort of children with univentricular hearts, focusing on the relation between HRV and surgical procedure. For 112 children with Fontan circulation, HRV was analyzed using power spectral analysis. Spectral power was determined in three regions: very-low-frequency (VLF), low-frequency (LF), and high-frequency (HF) regions. Patients were compared with 66 healthy controls subject. Patients with LT were compared with patients who had EC. The children with Fontan circulation showed a significantly reduced HRV including total power (P &lt; 0.0001), VLF (P &lt; 0.0001), LF (P &lt; 0.0001), and HF (P = 0.001) compared with the control subjects. The LT and EC patients did not differ significantly. Reduced HRV was found in both the LT and EC patients. In terms of HRV reduction, EC was not superior to LT.},
  author       = {Dahlqvist, Jenny Alenius and Karlsson, Marcus and Wiklund, Urban and Hornsten, Rolf and Stromvall-Larsson, Eva and Berggren, Hakan and Hanséus, Katarina and Johansson, Sune and Rydberg, Annika},
  issn         = {0172-0643},
  keyword      = {Extracardiac conduit,Fontan circulation,Heart rate variability,Lateral tunnel},
  language     = {eng},
  number       = {2},
  pages        = {307--315},
  publisher    = {Springer},
  series       = {Pediatric Cardiology},
  title        = {Heart Rate Variability in Children With Fontan Circulation: Lateral Tunnel and Extracardiac Conduit},
  url          = {http://dx.doi.org/10.1007/s00246-011-0126-2},
  volume       = {33},
  year         = {2012},
}