Anatomical and physiological foundations of cerebellar information processing
(2005) In Nature Reviews Neuroscience 6(4). p.297-311- Abstract
- A coordinated movement is easy to recognize, but we know little about how it is achieved. In search of the neural basis of coordination, we present a model of spinocerebellar interactions in which the structure-functional organizing principle is a division of the cerebellum into discrete microcomplexes. Each microcomplex is the recipient of a specific motor error signal-that is, a signal that conveys information about an inappropriate movement. These signals are encoded by spinal reflex circuits and conveyed to the cerebellar cortex through climbing fibre afferents. This organization reveals salient features of cerebellar information processing, but also highlights the importance of systems level analysis for a fuller understanding of the... (More)
- A coordinated movement is easy to recognize, but we know little about how it is achieved. In search of the neural basis of coordination, we present a model of spinocerebellar interactions in which the structure-functional organizing principle is a division of the cerebellum into discrete microcomplexes. Each microcomplex is the recipient of a specific motor error signal-that is, a signal that conveys information about an inappropriate movement. These signals are encoded by spinal reflex circuits and conveyed to the cerebellar cortex through climbing fibre afferents. This organization reveals salient features of cerebellar information processing, but also highlights the importance of systems level analysis for a fuller understanding of the neural mechanisms that underlie behaviour. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/247022
- author
- Apps, R and Garwicz, Martin LU
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Nature Reviews Neuroscience
- volume
- 6
- issue
- 4
- pages
- 297 - 311
- publisher
- Nature Publishing Group
- external identifiers
-
- pmid:15803161
- wos:000228092300013
- scopus:16344376363
- pmid:15803161
- ISSN
- 1471-003X
- DOI
- 10.1038/nrn1646
- language
- English
- LU publication?
- yes
- id
- 42f6fbf7-941e-4d57-8bf1-de09778527f6 (old id 247022)
- date added to LUP
- 2016-04-01 16:08:23
- date last changed
- 2022-04-15 02:21:59
@article{42f6fbf7-941e-4d57-8bf1-de09778527f6,
abstract = {{A coordinated movement is easy to recognize, but we know little about how it is achieved. In search of the neural basis of coordination, we present a model of spinocerebellar interactions in which the structure-functional organizing principle is a division of the cerebellum into discrete microcomplexes. Each microcomplex is the recipient of a specific motor error signal-that is, a signal that conveys information about an inappropriate movement. These signals are encoded by spinal reflex circuits and conveyed to the cerebellar cortex through climbing fibre afferents. This organization reveals salient features of cerebellar information processing, but also highlights the importance of systems level analysis for a fuller understanding of the neural mechanisms that underlie behaviour.}},
author = {{Apps, R and Garwicz, Martin}},
issn = {{1471-003X}},
language = {{eng}},
number = {{4}},
pages = {{297--311}},
publisher = {{Nature Publishing Group}},
series = {{Nature Reviews Neuroscience}},
title = {{Anatomical and physiological foundations of cerebellar information processing}},
url = {{http://dx.doi.org/10.1038/nrn1646}},
doi = {{10.1038/nrn1646}},
volume = {{6}},
year = {{2005}},
}