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Bacterial vaginosis - a microbiological and immunological enigma

Forsum, U; Holst, Elisabet LU ; Larsson, P G; Vasquez, Alejandra LU ; Jakobsson, T and Mattsby-Baltzer, I (2005) In Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS) 113(2). p.81-90
Abstract
The development of bacterial vaginosis (BV) among women of childbearing age and the resulting quantitative and qualitative shift from normally occurring lactobacilli in the vagina to a mixture of mainly anaerobic bacteria is a microbiological and immunological enigma that so far has precluded the formulation of a unifying generally accepted theory on the aetiology and clinical course of BV This critical review highlights some of the more important aspects of BV research that could help in formulating new basic ideas respecting the biology of BV not least the importance of the interleukin mediators of local inflammatory responses and the bacterial shift from the normally occurring lactobacilli species: L. crispatus, L. gasseri, L. jensenii,... (More)
The development of bacterial vaginosis (BV) among women of childbearing age and the resulting quantitative and qualitative shift from normally occurring lactobacilli in the vagina to a mixture of mainly anaerobic bacteria is a microbiological and immunological enigma that so far has precluded the formulation of a unifying generally accepted theory on the aetiology and clinical course of BV This critical review highlights some of the more important aspects of BV research that could help in formulating new basic ideas respecting the biology of BV not least the importance of the interleukin mediators of local inflammatory responses and the bacterial shift from the normally occurring lactobacilli species: L. crispatus, L. gasseri, L. jensenii, and L. iners to a mixed flora dominated by anaerobic bacteria. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
immune response, taxonomy, lactobacilli, bacterial vaginosis, ecology, nugent scoring
in
Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS)
volume
113
issue
2
pages
81 - 90
publisher
John Wiley & Sons
external identifiers
  • wos:000227626700001
  • pmid:15723682
  • scopus:14844320009
ISSN
1600-0463
DOI
10.1111/j.1600-0463.2005.apm1130201.x
language
English
LU publication?
yes
id
2bd934e0-6ac9-4d3e-a885-bf2ce70a5d45 (old id 249080)
date added to LUP
2007-08-06 14:33:23
date last changed
2017-09-10 03:31:41
@article{2bd934e0-6ac9-4d3e-a885-bf2ce70a5d45,
  abstract     = {The development of bacterial vaginosis (BV) among women of childbearing age and the resulting quantitative and qualitative shift from normally occurring lactobacilli in the vagina to a mixture of mainly anaerobic bacteria is a microbiological and immunological enigma that so far has precluded the formulation of a unifying generally accepted theory on the aetiology and clinical course of BV This critical review highlights some of the more important aspects of BV research that could help in formulating new basic ideas respecting the biology of BV not least the importance of the interleukin mediators of local inflammatory responses and the bacterial shift from the normally occurring lactobacilli species: L. crispatus, L. gasseri, L. jensenii, and L. iners to a mixed flora dominated by anaerobic bacteria.},
  author       = {Forsum, U and Holst, Elisabet and Larsson, P G and Vasquez, Alejandra and Jakobsson, T and Mattsby-Baltzer, I},
  issn         = {1600-0463},
  keyword      = {immune response,taxonomy,lactobacilli,bacterial vaginosis,ecology,nugent scoring},
  language     = {eng},
  number       = {2},
  pages        = {81--90},
  publisher    = {John Wiley & Sons},
  series       = {Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS)},
  title        = {Bacterial vaginosis - a microbiological and immunological enigma},
  url          = {http://dx.doi.org/10.1111/j.1600-0463.2005.apm1130201.x},
  volume       = {113},
  year         = {2005},
}