Spontaneous muscle twitches during sleep guide spinal self-organization.
Petersson, Per LU ; Waldenström Ellervik, Alexandra LU ; Fåhraeus, Christer LU and Schouenborg, Jens LU
(2003)
In Nature
424(6944).
p.72-75
- Abstract
- During development, information about the three-dimensional shape and mechanical properties of the body is laid down in the synaptic connectivity of sensorimotor systems through unknown adaptive mechanisms. In spinal reflex systems, this enables the fast transformation of complex sensory information into adequate correction of movements. Here we use a computer simulation to show that an unsupervised correlation-based learning mechanism, using spontaneous muscle twitches, can account for the functional adaptation of the withdrawal reflex system. We also show that tactile feedback resulting from spontaneous muscle twitches during sleep(1-3) does indeed modify sensorimotor transformation in young rats in a predictable manner. The results... (More)
- During development, information about the three-dimensional shape and mechanical properties of the body is laid down in the synaptic connectivity of sensorimotor systems through unknown adaptive mechanisms. In spinal reflex systems, this enables the fast transformation of complex sensory information into adequate correction of movements. Here we use a computer simulation to show that an unsupervised correlation-based learning mechanism, using spontaneous muscle twitches, can account for the functional adaptation of the withdrawal reflex system. We also show that tactile feedback resulting from spontaneous muscle twitches during sleep(1-3) does indeed modify sensorimotor transformation in young rats in a predictable manner. The results indicate that these twitches, corresponding to human fetal movements(4), are important in spinal self-organization. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/116522
- author
- Petersson, Per
LU
; Waldenström Ellervik, Alexandra
LU
; Fåhraeus, Christer
LU
and Schouenborg, Jens
LU
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Nature
- volume
- 424
- issue
- 6944
- pages
- 72 - 75
- publisher
- Nature Publishing Group
- external identifiers
-
- wos:000183912800042
- pmid:12840761
- scopus:0037926495
- pmid:12840761
- ISSN
- 0028-0836
- DOI
- 10.1038/nature01719
- language
- English
- LU publication?
- yes
- id
- 2550aa4c-2265-4cd0-9d15-1b0ba7c0fd26 (old id 116522)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12840761&dopt=Abstract
- date added to LUP
- 2016-04-01 12:09:47
- date last changed
- 2024-06-19 13:59:27
@article{2550aa4c-2265-4cd0-9d15-1b0ba7c0fd26,
abstract = {{During development, information about the three-dimensional shape and mechanical properties of the body is laid down in the synaptic connectivity of sensorimotor systems through unknown adaptive mechanisms. In spinal reflex systems, this enables the fast transformation of complex sensory information into adequate correction of movements. Here we use a computer simulation to show that an unsupervised correlation-based learning mechanism, using spontaneous muscle twitches, can account for the functional adaptation of the withdrawal reflex system. We also show that tactile feedback resulting from spontaneous muscle twitches during sleep(1-3) does indeed modify sensorimotor transformation in young rats in a predictable manner. The results indicate that these twitches, corresponding to human fetal movements(4), are important in spinal self-organization.}},
author = {{Petersson, Per and Waldenström Ellervik, Alexandra and Fåhraeus, Christer and Schouenborg, Jens}},
issn = {{0028-0836}},
language = {{eng}},
number = {{6944}},
pages = {{72--75}},
publisher = {{Nature Publishing Group}},
series = {{Nature}},
title = {{Spontaneous muscle twitches during sleep guide spinal self-organization.}},
url = {{http://dx.doi.org/10.1038/nature01719}},
doi = {{10.1038/nature01719}},
volume = {{424}},
year = {{2003}},
}