Acupuncture compared with placebo acupuncture in radiotherapy-induced nausea-a randomized controlled study
(2012) In Annals of Oncology 23(5). p.1353-1361- Abstract
- It is not known if verum (real) acupuncture is effective for nausea and vomiting (emesis) during radiotherapy. We randomly treated 215 blinded cancer patients with verum: penetrating 'deqi' creating acupuncture (n = 109) or non-penetrating sham needles (n = 106) two to three times per week. The patients documented emesis daily during the radiotherapy period. Primary end point was the number of patients with at least one episode of nausea. In the verum and the sham acupuncture group, 70% and 62% experienced nausea at least once during the radiotherapy period (relative risk 1.1, 95% CI 0.9-1.4) for a mean number of 10.1 and 8.7 days. Twenty five percent and 28% vomited, and 42% and 37% used antiemetic drugs at least once, respectively.... (More)
- It is not known if verum (real) acupuncture is effective for nausea and vomiting (emesis) during radiotherapy. We randomly treated 215 blinded cancer patients with verum: penetrating 'deqi' creating acupuncture (n = 109) or non-penetrating sham needles (n = 106) two to three times per week. The patients documented emesis daily during the radiotherapy period. Primary end point was the number of patients with at least one episode of nausea. In the verum and the sham acupuncture group, 70% and 62% experienced nausea at least once during the radiotherapy period (relative risk 1.1, 95% CI 0.9-1.4) for a mean number of 10.1 and 8.7 days. Twenty five percent and 28% vomited, and 42% and 37% used antiemetic drugs at least once, respectively. Ninety-five percent in the verum acupuncture group and 96% in the sham acupuncture group believed that the treatment had been effective against nausea. In both groups, 67% experienced positive effects on relaxation, mood, sleep or pain reduction and 89% wished to receive the treatment again. Acupuncture creating deqi is not more effective than sham in radiotherapy-induced nausea, but in this study, nearly all patients in both groups experienced that the treatment was effective for nausea. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2551622
- author
- Enblom, A. ; Johnsson, Anna LU ; Hammar, M. ; Onelov, E. ; Steineck, G. and Borjeson, S.
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- acupuncture therapy, cancer, complementary medicine, emesis, radiotherapy
- in
- Annals of Oncology
- volume
- 23
- issue
- 5
- pages
- 1353 - 1361
- publisher
- Oxford University Press
- external identifiers
-
- wos:000303336400040
- scopus:84860491247
- pmid:21948812
- ISSN
- 1569-8041
- DOI
- 10.1093/annonc/mdr402
- language
- English
- LU publication?
- yes
- id
- e38c9924-276e-481f-b97a-4bf33cd47d69 (old id 2551622)
- date added to LUP
- 2016-04-01 13:21:13
- date last changed
- 2022-03-21 18:02:02
@article{e38c9924-276e-481f-b97a-4bf33cd47d69,
abstract = {{It is not known if verum (real) acupuncture is effective for nausea and vomiting (emesis) during radiotherapy. We randomly treated 215 blinded cancer patients with verum: penetrating 'deqi' creating acupuncture (n = 109) or non-penetrating sham needles (n = 106) two to three times per week. The patients documented emesis daily during the radiotherapy period. Primary end point was the number of patients with at least one episode of nausea. In the verum and the sham acupuncture group, 70% and 62% experienced nausea at least once during the radiotherapy period (relative risk 1.1, 95% CI 0.9-1.4) for a mean number of 10.1 and 8.7 days. Twenty five percent and 28% vomited, and 42% and 37% used antiemetic drugs at least once, respectively. Ninety-five percent in the verum acupuncture group and 96% in the sham acupuncture group believed that the treatment had been effective against nausea. In both groups, 67% experienced positive effects on relaxation, mood, sleep or pain reduction and 89% wished to receive the treatment again. Acupuncture creating deqi is not more effective than sham in radiotherapy-induced nausea, but in this study, nearly all patients in both groups experienced that the treatment was effective for nausea.}},
author = {{Enblom, A. and Johnsson, Anna and Hammar, M. and Onelov, E. and Steineck, G. and Borjeson, S.}},
issn = {{1569-8041}},
keywords = {{acupuncture therapy; cancer; complementary medicine; emesis; radiotherapy}},
language = {{eng}},
number = {{5}},
pages = {{1353--1361}},
publisher = {{Oxford University Press}},
series = {{Annals of Oncology}},
title = {{Acupuncture compared with placebo acupuncture in radiotherapy-induced nausea-a randomized controlled study}},
url = {{http://dx.doi.org/10.1093/annonc/mdr402}},
doi = {{10.1093/annonc/mdr402}},
volume = {{23}},
year = {{2012}},
}