Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Enantioselective synthesis of anti-beta-amido-alpha-hydroxy esters via asymmetric transfer hydrogenation coupled with dynamic kinetic resolution

Villacrez, Marvin LU and Somfai, Peter LU (2013) In Tetrahedron Letters 54(38). p.5266-5268
Abstract
The asymmetric transfer hydrogenation of beta-amido-alpha-keto esters providing the corresponding anti-beta-amido-alpha-hydroxy esters via dynamic kinetic resolution is reported. The use of a commercially available, or simply prepared, chiral ruthenium catalyst results in good yields as well as high diastereoselectivities and enantioselectivities. (C) 2013 Elsevier Ltd. All rights reserved.
Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Ruthenium, Dynamic kinetic resolution, Asymmetric transfer hydrogenation, Enantioselective, 1, 2-Amino alcohols
in
Tetrahedron Letters
volume
54
issue
38
pages
5266 - 5268
publisher
Elsevier
external identifiers
  • wos:000323589300032
  • scopus:84881609817
ISSN
0040-4039
DOI
10.1016/j.tetlet.2013.07.100
language
English
LU publication?
yes
id
258ff45a-8b22-48eb-bfe0-85151b026e0a (old id 4062713)
date added to LUP
2016-04-01 13:12:41
date last changed
2024-04-10 02:11:05
@article{258ff45a-8b22-48eb-bfe0-85151b026e0a,
  abstract     = {{The asymmetric transfer hydrogenation of beta-amido-alpha-keto esters providing the corresponding anti-beta-amido-alpha-hydroxy esters via dynamic kinetic resolution is reported. The use of a commercially available, or simply prepared, chiral ruthenium catalyst results in good yields as well as high diastereoselectivities and enantioselectivities. (C) 2013 Elsevier Ltd. All rights reserved.}},
  author       = {{Villacrez, Marvin and Somfai, Peter}},
  issn         = {{0040-4039}},
  keywords     = {{Ruthenium; Dynamic kinetic resolution; Asymmetric transfer hydrogenation; Enantioselective; 1; 2-Amino alcohols}},
  language     = {{eng}},
  number       = {{38}},
  pages        = {{5266--5268}},
  publisher    = {{Elsevier}},
  series       = {{Tetrahedron Letters}},
  title        = {{Enantioselective synthesis of anti-beta-amido-alpha-hydroxy esters via asymmetric transfer hydrogenation coupled with dynamic kinetic resolution}},
  url          = {{http://dx.doi.org/10.1016/j.tetlet.2013.07.100}},
  doi          = {{10.1016/j.tetlet.2013.07.100}},
  volume       = {{54}},
  year         = {{2013}},
}