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Update on biofilm infections in the urinary tract

Tenke, Peter; Koeves, Bela; Nagy, Karoly; Hultgren, Scott J.; Mendling, Werner; Wullt, Björn LU ; Grabe, Magnus LU ; Wagenlehner, Florian M. E.; Cek, Mete and Pickard, Robert, et al. (2012) In World Journal of Urology 30(1). p.51-57
Abstract
Purpose Biofilm infections have a major role in implants or devices placed in the human body. As part of the endourological development, a great variety of foreign bodies have been designed, and with the increasing number of biomaterial devices used in urology, biofilm formation and device infection is an issue of growing importance. Methods A literature search was performed in the Medline database regarding biofilm formation and the role of biofilms in urogenital infections using the following items in different combinations: "biofilm," "urinary tract infection," "bacteriuria," "catheter," "stent," and "encrustation." The studies were graded using the Oxford Centre for Evidence-based Medicine classification. Results The authors present an... (More)
Purpose Biofilm infections have a major role in implants or devices placed in the human body. As part of the endourological development, a great variety of foreign bodies have been designed, and with the increasing number of biomaterial devices used in urology, biofilm formation and device infection is an issue of growing importance. Methods A literature search was performed in the Medline database regarding biofilm formation and the role of biofilms in urogenital infections using the following items in different combinations: "biofilm," "urinary tract infection," "bacteriuria," "catheter," "stent," and "encrustation." The studies were graded using the Oxford Centre for Evidence-based Medicine classification. Results The authors present an update on the mechanism of biofilm formation in the urinary tract with special emphasis on the role of biofilms in lower and upper urinary tract infections, as well as on biofilm formation on foreign bodies, such as catheters, ureteral stents, stones, implants, and artificial urinary sphincters. The authors also summarize the different methods developed to prevent biofilm formation on urinary foreign bodies. Conclusions Several different approaches are being investigated for preventing biofilm formation, and some promising results have been obtained. However, an ideal method has not been developed. Future researches have to aim at identifying effective mechanisms for controlling biofilm formation and to develop antimicrobial agents effective against bacteria in biofilms. (Less)
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Contribution to journal
publication status
published
subject
keywords
Biofilm, Urinary tract infection, Catheter, Encrustation
in
World Journal of Urology
volume
30
issue
1
pages
51 - 57
publisher
Springer
external identifiers
  • wos:000302405800007
  • scopus:84856224136
ISSN
1433-8726
DOI
10.1007/s00345-011-0689-9
language
English
LU publication?
yes
id
987e7049-53c6-4ed3-bcd3-c2f7fd97036e (old id 2594556)
date added to LUP
2012-06-01 09:38:13
date last changed
2017-10-22 04:21:48
@article{987e7049-53c6-4ed3-bcd3-c2f7fd97036e,
  abstract     = {Purpose Biofilm infections have a major role in implants or devices placed in the human body. As part of the endourological development, a great variety of foreign bodies have been designed, and with the increasing number of biomaterial devices used in urology, biofilm formation and device infection is an issue of growing importance. Methods A literature search was performed in the Medline database regarding biofilm formation and the role of biofilms in urogenital infections using the following items in different combinations: "biofilm," "urinary tract infection," "bacteriuria," "catheter," "stent," and "encrustation." The studies were graded using the Oxford Centre for Evidence-based Medicine classification. Results The authors present an update on the mechanism of biofilm formation in the urinary tract with special emphasis on the role of biofilms in lower and upper urinary tract infections, as well as on biofilm formation on foreign bodies, such as catheters, ureteral stents, stones, implants, and artificial urinary sphincters. The authors also summarize the different methods developed to prevent biofilm formation on urinary foreign bodies. Conclusions Several different approaches are being investigated for preventing biofilm formation, and some promising results have been obtained. However, an ideal method has not been developed. Future researches have to aim at identifying effective mechanisms for controlling biofilm formation and to develop antimicrobial agents effective against bacteria in biofilms.},
  author       = {Tenke, Peter and Koeves, Bela and Nagy, Karoly and Hultgren, Scott J. and Mendling, Werner and Wullt, Björn and Grabe, Magnus and Wagenlehner, Florian M. E. and Cek, Mete and Pickard, Robert and Botto, Henry and Naber, Kurt G. and Johansen, Truls E. Bjerklund},
  issn         = {1433-8726},
  keyword      = {Biofilm,Urinary tract infection,Catheter,Encrustation},
  language     = {eng},
  number       = {1},
  pages        = {51--57},
  publisher    = {Springer},
  series       = {World Journal of Urology},
  title        = {Update on biofilm infections in the urinary tract},
  url          = {http://dx.doi.org/10.1007/s00345-011-0689-9},
  volume       = {30},
  year         = {2012},
}