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Asexuals, Polyploids, Evolutionary Opportunists ...: The Population Genetics of Positive but Deteriorating Mutations.

Bengtsson, Bengt Olle LU (2012) In Genetics 191(4). p.499-1393
Abstract
Some genetic phenomena originate as mutations that are initially advantageous but decline in fitness until they become distinctly deleterious. Here I give the condition for a mutation-selection balance to form and describe some of the properties of the resulting equilibrium population. A characterization is also given of the fixation probabilities for such mutations.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
mutation, mutational load, probability of fixation, selecttion
in
Genetics
volume
191
issue
4
pages
499 - 1393
publisher
Genetics Society of America
external identifiers
  • wos:000309000500028
  • pmid:22595245
  • scopus:84865083724
ISSN
0016-6731
DOI
10.1534/genetics.112.140715
language
English
LU publication?
yes
id
54f9895c-590f-4340-be79-77a385f2f317 (old id 2608761)
date added to LUP
2012-06-11 13:48:48
date last changed
2017-01-01 04:05:42
@article{54f9895c-590f-4340-be79-77a385f2f317,
  abstract     = {Some genetic phenomena originate as mutations that are initially advantageous but decline in fitness until they become distinctly deleterious. Here I give the condition for a mutation-selection balance to form and describe some of the properties of the resulting equilibrium population. A characterization is also given of the fixation probabilities for such mutations.},
  author       = {Bengtsson, Bengt Olle},
  issn         = {0016-6731},
  keyword      = {mutation,mutational load,probability of fixation,selecttion},
  language     = {eng},
  number       = {4},
  pages        = {499--1393},
  publisher    = {Genetics Society of America},
  series       = {Genetics},
  title        = {Asexuals, Polyploids, Evolutionary Opportunists ...: The Population Genetics of Positive but Deteriorating Mutations.},
  url          = {http://dx.doi.org/10.1534/genetics.112.140715},
  volume       = {191},
  year         = {2012},
}